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There is evidence for a function of acetylcholine in the cochlear nucleus, primarily in a feedback, modulatory effect on auditory processing. Using a microdissection and quantitative microassay approach, choline acetyltransferase activity was mapped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d096700a7fe3786fce39efe1c7722e
https://europepmc.org/articles/PMC6240496/
https://europepmc.org/articles/PMC6240496/
Autor:
Jon D. Dunn, Mark J. Frilling, Donald A. Godfrey, C. David Ross, Gregory J. Wiet, Judy A. Parli
Publikováno v:
Hearing research. 356
Although it is well established that the choline acetyltransferase (ChAT, the enzyme for acetylcholine synthesis) in the mammalian cochlea is associated with its olivocochlear innervation, the distribution of this innervation in the cochlea varies so
Publikováno v:
Neurochemical Research. 20:1483-1490
Homogenates of specific brain regions of three sensory systems (auditory, olfactory, and visual) were prepared from pigmented Long-Evans Hooded rats and assayed for amino acid concentrations and activities of glutaminase, aspartate aminotransferase (
Publikováno v:
Neurochemical Research. 19:693-703
The quantitative distributions of aspartate aminotransferase and glutaminase were mapped in subregions of olfactory bulb and cochlear nucleus of rat, and were compared with similar data for retina and with the distributions of their substrate and pro
Publikováno v:
Hearing Research. 48:187-194
To further investigate the peculiar characteristics of the middle ear and extraocular muscles, compared to the extensively studied skeletal muscles of the limbs, activities of enzymes of transmitter and energy metabolism were measured in homogenates
Publikováno v:
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 103(5 ( Pt 1))
Activities of the enzymes choline acetyltransferase (ChAT) and acetylcholinesterase (AChE), which metabolize the neuromuscular transmitter acetylcholine, and malate and lactate dehydrogenase (MDH and LDH), enzymes of oxidative and glycolytic energy m
Publikováno v:
Hearing research. 49(1-3)
Using a quantitative microchemical mapping approach combined with surgical cuts of fiber tracts, the contributions of centrifugal pathways to choline acetyltransferase activity were mapped three-dimensionally in the cat cochlear nucleus. Large reduct
Publikováno v:
Vision Research. 29:1079-1084
Concentrations of glutamate, aspartate, glutamine, glycine, GABA, and taurine were determined in samples microdissected from rat retinal layers and assayed by HPLC. Glutamate and glutamine were relatively high in the inner nuclear (INL) and ganglion
Publikováno v:
Biochimica et biophysica acta. 925(2)
The properties of the cytosolic and mitochondrial isoenzymes of aspartate aminotransferase were studied using a commercial preparation of the cytosolic isoenzyme, a mitochondrial preparation, and whole brain homogenate. Based on these properties, mic
Publikováno v:
Neurochemical Research; Jun1994, Vol. 19 Issue 6, p693-703, 11p