Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Judy L. Bolton"'
Autor:
Atieh Hajirahimkhan, Caitlin Howell, Elizabeth T. Bartom, Huali Dong, Daniel D. Lantvit, Xiaoling Xuei, Shao-Nong Chen, Guido F. Pauli, Judy L. Bolton, Susan E. Clare, Seema A. Khan, Birgit M. Dietz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Breast cancer risk continues to increase post menopause. Anti-estrogen therapies are available to prevent postmenopausal breast cancer in high-risk women. However, their adverse effects have reduced acceptability and overall success in cance
Externí odkaz:
https://doaj.org/article/b8f59066aa7a47d7acf8ab8b42dc1051
Autor:
Gregory R.J. Thatcher, Judy L. Bolton, Marton I. Siklos, Rui Xiong, Bradley T. Michalsen, Robert A. Scism, Emily N. Thayer, Yijin Wang, Shuai Wang, Sujeewa C. Piyankarage, Jaewoo Choi, R. Esala P. Chandrasena, Hitisha Patel, L.P. Madhubhani P. Hemachandra
The risk of developing hormone-dependent cancers with long-term exposure to estrogens is attributed both to proliferative, hormonal actions at the estrogen receptor (ER) and to chemical carcinogenesis elicited by genotoxic, oxidative estrogen metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c9bdf2f7a62eabcf8004690574fdef4
https://doi.org/10.1158/1940-6207.c.6544512
https://doi.org/10.1158/1940-6207.c.6544512
Autor:
Judy L. Bolton, Gregory R.J. Thatcher, Guido F. Pauli, Birgit M. Dietz, Robert A. Scism, David C. Lankin, Matthew Main, Shao-Nong Chen, P. Esala, R. Chandrasena, P. Madhubhani, L.P. Hemachandra
Long-term exposure to estrogens including those in traditional hormone replacement therapy (HRT) increases the risk of developing hormone-dependent cancers. As a result, women are turning to over-the-counter (OTC) botanical dietary supplements, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2af6c6cf4ef98cad8053033ab957eaf
https://doi.org/10.1158/1940-6207.c.6544635
https://doi.org/10.1158/1940-6207.c.6544635
Autor:
Gregory R.J. Thatcher, Judy L. Bolton, Marton I. Siklos, Rui Xiong, Bradley T. Michalsen, Robert A. Scism, Emily N. Thayer, Yijin Wang, Shuai Wang, Sujeewa C. Piyankarage, Jaewoo Choi, R. Esala P. Chandrasena, Hitisha Patel, L.P. Madhubhani P. Hemachandra
PDF file - 391K, Supplementary Figure S1: Recombinant COMT (10 microg/mL) was incubated with S-(5'-adenosyl)-L-methionine (500 nM) and raloxifene, DMA, or bazadoxifene (1 microM ) at 37 degrees C for 5 minutes prior to the addition of 6,7-dihydroxyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdad968c2164fd8129f4d51c4467a09
https://doi.org/10.1158/1940-6207.22524975.v1
https://doi.org/10.1158/1940-6207.22524975.v1
Autor:
Judy L. Bolton, Gregory R.J. Thatcher, Guido F. Pauli, Birgit M. Dietz, Robert A. Scism, David C. Lankin, Matthew Main, Shao-Nong Chen, P. Esala, R. Chandrasena, P. Madhubhani, L.P. Hemachandra
PDf file - 294K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a1ef25ae0847792275d53d2dafcd12
https://doi.org/10.1158/1940-6207.22525224
https://doi.org/10.1158/1940-6207.22525224
Autor:
Atieh Hajirahimkhan, Caitlin Howell, Shao-Nong Chen, Susan E. Clare, Guido F. Pauli, Seema A. Khan, Judy L. Bolton, Birgit M. Dietz
Breast cancer risk continues to rise post menopause. Endocrine therapies are employed to prevent postmenopausal breast cancer in high-risk women. However, their adverse effects have reduced acceptability and overall success in cancer preventionatural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a929067be74af72176b4a9ce04475be
https://doi.org/10.1101/2022.05.06.490985
https://doi.org/10.1101/2022.05.06.490985
Autor:
Jaewoo Choi, Elena I. Barengolts, Richard B. van Breemen, Scott W. Leonard, Luying Chen, Judy L. Bolton, Suzanne Banuvar, Shao-Nong Chen, Marlos A. G. Viana, Guido F. Pauli
Publikováno v:
J Agric Food Chem
Extracts of red clover (Trifolium pratense L.), containing estrogenic isoflavones like genistein and daidzein and the proestrogenic isoflavones formononetin and biochanin A, are used by women as dietary supplements for the management of menopausal sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3312ad55e2229e29d4b01005dbc816
https://doi.org/10.1021/acs.jafc.0c05856
https://doi.org/10.1021/acs.jafc.0c05856
Autor:
Caitlin E. Howell, Tareisha L. Dunlap, Birgit M. Dietz, Günter Vollmer, Guido F. Pauli, Shao-Nong Chen, Ryan T. Hitzman, Judy L. Bolton
Publikováno v:
Chemical Research in Toxicology. 33:2793-2803
Botanical dietary supplements (BDS) containing hops are sold as women's health supplements due to the potent hop phytoestrogen, 8-prenylnaringenin (8-PN), and the cytoprotective chalcone, xanthohumol. Previous studies have shown a standardized hop ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213da9f3bc7adee2a6c28103cdb2b718
https://doi.org/10.1021/acs.chemrestox.0c00194
https://doi.org/10.1021/acs.chemrestox.0c00194
Autor:
René F. Ramos Alvarenga, Martin Biendl, Guido F. Pauli, Judy L. Bolton, Shao-Nong Chen, Huali Dong, Dejan Nikolic, Richard B. van Breemen, Birgit M. Dietz
Publikováno v:
Journal of Natural Products
Botanical dietary supplements contain multiple bioactive compounds that target numerous biological pathways. The lack of uniform standardization requirements is one reason that inconsistent clinical effects are reported frequently. The multifaceted b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4f7df873ccfd8baefd9975a3efc767
Autor:
Caitlin E. Howell, Judy L. Bolton, Susan E. Clare, Atieh Hajirahimkhan, Seema A. Khan, Guido F. Pauli, Shao-Nong Chen, Tareisha L. Dunlap, Birgit M. Dietz
Publikováno v:
Cancer Research. 81:PS8-10
Introduction: Breast cancer risk continues to rise following menopause, despite the cessation of ovarian estrogen synthesis. Pathways involving increased aromatase activity and inflammation in the breast microenvironment are implicated. Their concert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3c191b08cce1992af9eaf9cef8ef3e
https://doi.org/10.1158/1538-7445.sabcs20-ps8-10
https://doi.org/10.1158/1538-7445.sabcs20-ps8-10