Výsledky vyhledávání - "Judith S. Walker"

Anti-inflammatory effects of κ-opioids: relevance to rheumatoid arthritis

Autor: Judith S Walker

Publikováno v: Pain Reviews. 8:113-119

Therapy with opioids is an exciting new development for arthritis, especially since there is the potential for fewer side effects from molecules that act outside the central nervous system. We have found k-opioid drugs to be powerfully anti-in eammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ede8dae472fae889a1aa57e4a3d8d246
https://doi.org/10.1191/0968130201pr181ra

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Zinc alleviates thermal hyperalgesia due to partial nerve injury

Autor: David J. Tracey, Judith S. Walker, Tao Liu

Publikováno v: NeuroReport. 10:1619-1623

Zinc has recently been shown to alleviate inflammatory hyperalgesia. In the present study, we showed that intrathecal, intraplantar or systemic injection of zinc chloride significantly relieved thermal hyperalgesia in rats with sciatic nerve injury.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b58cc4f15e020510b8b0223695241f0
https://doi.org/10.1097/00001756-199905140-00042

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Experimental Pain in Healthy Human Subjects

Autor: JUDITH S. WALKER, JOHN J. CARMODY

Publikováno v: Anesthesia & Analgesia. 86:1257-1262

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673696e7669fc3f4495eb135da0c3d6a
https://doi.org/10.1213/00000539-199806000-00023

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Gender differences in pain

Autor: Belinda E. Giles, Judith S. Walker

Publikováno v: Current opinion in anaesthesiology. 12(5)

A literature survey reveals clear evidence of sex differences in the incidence of painful conditions and their severity, both being greater in women. The possible causes of this sexual dimorphism are discussed. Sex-role stereotyping may be relevant a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b755b6976bbfaa4d158e9b8332dc4c6
https://pubmed.ncbi.nlm.nih.gov/17016254

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Anti-inflammatory effects of opioids

Autor: Judith S, Walker

Publikováno v: Advances in experimental medicine and biology. 521

In summary, therapy with opioids is an exciting new development for arthritis especially since there is the potential for fewer side effects from molecules which act outside the CNS. We found kappa-opioid drugs to be powerfully anti-inflammatory, red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a44d4df30890b4cc333dda682784965
https://pubmed.ncbi.nlm.nih.gov/12617572

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Pharmacokinetic-pharmacodynamic relationships of morphine in neonates

Autor: Judith S Walker, Barry J Duffy, Paul C W Chay

Publikováno v: Clinical pharmacology and therapeutics. 51(3)

Morphine pharmacokinetics and pharmacodynamics (analgesia and sedation) were evaluated after continuous intravenous infusion of morphine in 19 neonates, both preterm and term, whose lungs were ventilated to relieve respiratory distress. Elimination h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd24ba48853f4d339f205363be0ae67c
https://pubmed.ncbi.nlm.nih.gov/1544290

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Effect of multiple dosing on the analgesic action of diflunisal in rats

Autor: Gerhard Levy, Judith S. Walker

Publikováno v: Life sciences. 46(10)

This investigation was designed to compare the analgesic effect of the initial dose of a repetitively dosed non-narcotic analgesic with the analgesic effect of a subsequent dose given 3 days later. To exclude gradual drug accumulation as a variable,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1bdfc533d2f7bc20211ec524d73c63
https://pubmed.ncbi.nlm.nih.gov/2314196

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[Untitled]

Autor: Judith S. Walker, Gerhard Levy, Patricia M. Klockowski

Publikováno v: Pharmaceutical Research. :404-407

This investigation was designed to determine the effect of experimental hyperthyroidism on the hypnotic activity of a benzodiazepine and on the binding characteristics of the benzodiazepine receptor complex. Rats were made hyperthyroid by subcutaneou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c6fc0aeac0470046e2c46a7ef106e63
https://doi.org/10.1023/a:1015983415887

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Induction of experimental thyroid dysfunction in rats with implantable pellets of thyroxine or propylthiouracil

Autor: Gerhard Levy, Judith S. Walker

Publikováno v: Journal of Pharmacological Methods. 21:223-229

Subcutaneously implanted pellets containing the thyroid hormone thyroxine or the thyrotoxic agent propylthiouracil were used to induce hyper- or hypothyroidism in rats. The results obtained were compared to those produced by daily subcutaneous inject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3281d8c2e8f9f05ac3692e6d8f8502
https://doi.org/10.1016/0160-5402(89)90056-9

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