Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Judith S. Hecker"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/2f68d51f06f344c2a701740db6b4ca46
Autor:
Jennifer Rivière, Jennifer Hock, Michèle C. Buck, Judith S. Hecker, Katharina S. Götze, Mark van der Garde
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-5 (2023)
Abstract Bone marrow samples from discarded femoral heads are often used as healthy controls in studies investigating the in vitro characteristics of cells from patients with hematologic malignancies. Since patient samples are usually derived from il
Externí odkaz:
https://doaj.org/article/48a4a791f90543699bfb5f5fb099ad02
Autor:
Michèle C. Buck, Lisa Bast, Judith S. Hecker, Jennifer Rivière, Maja Rothenberg-Thurley, Luisa Vogel, Dantong Wang, Immanuel Andrä, Fabian J. Theis, Florian Bassermann, Klaus H. Metzeler, Robert A.J. Oostendorp, Carsten Marr, Katharina S. Götze
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107328- (2023)
Summary: Clonal hematopoiesis of indeterminate potential (CHIP) describes the age-related acquisition of somatic mutations in hematopoietic stem/progenitor cells (HSPC) leading to clonal blood cell expansion. Although CHIP mutations drive myeloid mal
Externí odkaz:
https://doaj.org/article/a281b751b3e543528abcca4b0e8c1c42
Autor:
Jonas B. Lang, Michèle C. Buck, Jennifer Rivière, Oumaima Stambouli, Ken Sachenbacher, Purva Choudhary, Hendrik Dietz, Bernd Giebel, Florian Bassermann, Robert A. J. Oostendorp, Katharina S. Götze, Judith S. Hecker
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cellular crosstalk between hematopoietic stem/progenitor cells and the bone marrow (BM) niche is vital for the development and maintenance of myeloid malignancies. These compartments can communicate via bidirectional transfer of extracellular vesicle
Externí odkaz:
https://doaj.org/article/92af26feecd248e38ec35aba980990fc
Autor:
Krischan Braitsch, Laura K. Schmalbrock, Paul Jung, Irmgard Bumeder, Philipp Kiewe, Judith S. Hecker, Mareike Verbeek, Jörg Westermann, Lars Bullinger, Ulrich Keller, Florian Bassermann, Jan Krönke, Katharina S. Götze, Kathrin Rieger
Publikováno v:
HemaSphere, Vol 6, Iss 9, p e759 (2022)
Externí odkaz:
https://doaj.org/article/666804ca465842959a4be489c2e94e0d
Autor:
Judith S. Hecker, Adam Wahida, Erik Hameister, Aneta Filo, Jürgen Ruland, Florian Bassermann, Martin Hildebrandt, Mareike Verbeek, Hendrik Poeck
Publikováno v:
eJHaem, Vol 2, Iss 2, Pp 280-284 (2021)
Abstract Allogeneic hematopoietic stem cell transplantations (HSCTs) represent a curative strategy for treating hematologic malignancies yet bear dangerous and frequently life‐threatening complications including the development of graft‐versus‐
Externí odkaz:
https://doaj.org/article/d5c481200c764469ac09592f04efcad9
Autor:
Marie-Theresa Weickert, Judith S. Hecker, Michèle C. Buck, Christina Schreck, Jennifer Rivière, Matthias Schiemann, Katharina Schallmoser, Florian Bassermann, Dirk Strunk, Robert A. J. Oostendorp, Katharina S. Götze
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell disorders with a poor prognosis, especially for elderly patients. Increasing evidence suggests that alterations in the non-hematopoietic micr
Externí odkaz:
https://doaj.org/article/c226cd0ba70e465cbd553e5471ceb2e7
Autor:
Lisa Bast, Michèle C. Buck, Judith S. Hecker, Robert A.J. Oostendorp, Katharina S. Götze, Carsten Marr
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102120- (2021)
Summary: Classically, hematopoietic stem cell (HSC) differentiation is assumed to occur via progenitor compartments of decreasing plasticity and increasing maturity in a specific, hierarchical manner. The classical hierarchy has been challenged in th
Externí odkaz:
https://doaj.org/article/84b47e632be44c699018e93849d6d76f
Autor:
Dirk Strunk, Terry P Yamaguchi, Sandra Romero Marquez, Rouzanna Istvanffy, Michèle C. Buck, Jennifer Rivière, Katharina Brandstetter, Franziska Hettler, Matthias Kieslinger, Akiko Shimamura, Florian Bassermann, Mehmet Sacma, Hartmut Geiger, Erik Hameister, Jürgen Ruland, Christina Schreck, Heinrich Leonhardt, Theresa Landspersky, Robert A.J. Oostendorp, Judith S. Hecker, Kasiani C. Myers, Matthias Schiemann, Marilena Götz, Romina Ludwig, Martin Wolf, Katharina Götze
Publikováno v:
Blood
The cellular mechanisms required to ensure homeostasis of the hematopoietic niche and the ability of this niche to support hematopoiesis upon stress remain elusive. We here identify Wnt5a in Osterix+ mesenchymal progenitor and stem cells (MSPCs) as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9f1d995fee5c2e70935d49191a131c
https://doi.org/10.1182/blood.2021011775
https://doi.org/10.1182/blood.2021011775
Autor:
Martina Rauner, Lorenz C. Hofbauer, Judith S. Hecker, Katharina Götze, Elena Tsourdi, A. Roth, Martin Nolde, Luise Hartmann, Karsten Spiekermann, Carsten Marr, Susann Winter, Bianka Ksienzyk, Marie Schneider, Uwe Platzbecker, Katja Sockel, Klaus H. Metzeler, Dominikus Hausmann, Luise Fischer, Florian Bassermann, Mark van der Garde, Maria Solovey, Frank Ziemann, A.S. Kubasch, Maja Rothenberg-Thurley, Alexander C. Paulus, Michèle C. Buck, Jörg Lützner, Jennifer Rivière
Publikováno v:
Blood
Clonal hematopoiesis (CH) is an age-related condition predisposing to blood cancer and cardiovascular disease (CVD). Murine models demonstrate CH-mediated altered immune function and proinflammation. Low-grade inflammation has been implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1103d06c0c2a414084d71d2ef2145aad
https://doi.org/10.1182/blood.2020010163
https://doi.org/10.1182/blood.2020010163