Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Judith R, Homberg"'
Autor:
Ling Shan, Harm J. Heusinkveld, Kimberly C. Paul, Samantha Hughes, Sirwan K. L. Darweesh, Bastiaan R. Bloem, Judith R. Homberg
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Parkinson’s disease (PD) is a chronic, progressive and disabling neurodegenerative disorder. The prevalence of PD has risen considerably over the past decades. A growing body of evidence suggest that exposure to environmental toxins, inclu
Externí odkaz:
https://doaj.org/article/862a3c57c24a4241a9c872cb14337747
Autor:
Xianzong Meng, Ping Chen, Andor Veltien, Tony Palavra, Sjors In't Veld, Joanes Grandjean, Judith R. Homberg
Publikováno v:
Neurobiology of Stress, Vol 28, Iss , Pp 100585- (2024)
Animals need to respond to threats to avoid danger and approach rewards. In nature, these responses did not evolve alone but are always accompanied by motivational conflict. A semi-naturalistic threat imminence continuum model models the approach-avo
Externí odkaz:
https://doaj.org/article/c114f2f29e414a4ba298e40bf7477fc5
Autor:
Bart C. J. Dirven, Dewi van der Geugten, Carolina Temporão, Miranda van Bodegom, Leonie Madder, Laura van Agen, Judith R. Homberg, Tamas Kozicz, Marloes J.A.G. Henckens
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Post-traumatic stress disorder (PTSD) is a psychiatric disorder vulnerable individuals can develop following a traumatic event, whereas others are resilient. Enhanced insight into the mechanistic underpinnings contributing to these inter-ind
Externí odkaz:
https://doaj.org/article/ac7d93a239e14190b2b70e5490f73268
Autor:
Ciara J. Molloy, Jennifer Cooke, Nicholas J. F. Gatford, Alejandro Rivera-Olvera, Sahar Avazzadeh, Judith R. Homberg, Joanes Grandjean, Cathy Fernandes, Sanbing Shen, Eva Loth, Deepak P. Srivastava, Louise Gallagher
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Multiple molecular pathways and cellular processes have been implicated in the neurobiology of autism and other neurodevelopmental conditions. There is a current focus on synaptic gene conditions, or synaptopathies, which refer to clinical conditions
Externí odkaz:
https://doaj.org/article/ab78ebda8b4e45e686f2ae9356555a2f
Autor:
Marcia Spoelder, Yami Bright, Martine C. Morrison, Veerle van Kempen, Lilian de Groodt, Malvina Begalli, Nikita Schuijt, Eva Kruiger, Ronald Bulthuis, Gabriele Gross, Robert Kleemann, Janna A. van Diepen, Judith R. Homberg
Publikováno v:
Cells, Vol 12, Iss 20, p 2463 (2023)
Increased insulin levels may support the development of neural circuits involved in cognition, while chronic mild inflammation may also result in cognitive impairment. This study aimed to gain more insight into whether cognition is already impacted d
Externí odkaz:
https://doaj.org/article/5f7c28dc8ba0460b98f31c8e6763f2de
Autor:
Paola Brivio, Maria Teresa Gallo, Peter Karel, Giulia Cogi, Fabio Fumagalli, Judith R. Homberg, Francesca Calabrese
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Stress-related mental disorders encompass a plethora of pathologies that share the exposure to a negative environment as trigger for their development. The vulnerability to the effects of a negative environment is not equal to all but differs between
Externí odkaz:
https://doaj.org/article/f28ac37ea3f14ad3bfbab04ea77603af
Autor:
Anne Stephanie Mallien, Laura Becker, Natascha Pfeiffer, Federica Terraneo, Melissa Hahn, Anthonieke Middelman, Rupert Palme, Kerstin Camile Creutzberg, Veronica Begni, Marco Andrea Riva, Damiana Leo, Heidrun Potschka, Fabio Fumagalli, Judith R. Homberg, Peter Gass
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
In preclinical psychiatry research, animals are central to modeling and understanding biological mechanisms of behavior and psychiatric disorders. We here present the first multimodal severity assessment of a genetically modified rat strain used in p
Externí odkaz:
https://doaj.org/article/f01fe0dd64c74543a7a97544fd93975b
Autor:
Christian J. M. I. Klein, Thomas Budiman, Judith R. Homberg, Dilip Verma, Jaap Keijer, Evert M. van Schothorst
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/b7d84311cfd04bd7b9396d100eb467e8
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gestational stress can increase postpartum depression in women. To treat maternal depression, fluoxetine (FLX) is most commonly prescribed. While FLX may be effective for the mother, at high doses it may have adverse effects on the fetus. As
Externí odkaz:
https://doaj.org/article/a3cd98e110914cf59f35b31b853880e4
Autor:
Casper J. H. Wolf, Hanka Venselaar, Marcia Spoelder, Harmen Beurmanjer, Arnt F. A. Schellekens, Judith R. Homberg
Publikováno v:
Life, Vol 13, Iss 4, p 926 (2023)
The neurotransmitter γ-hydroxybutyric acid (GHB) is suggested to be involved in neuronal energy homeostasis processes, but the substance is also used as a recreational drug and as a prescription medication for narcolepsy. GHB has several high-affini
Externí odkaz:
https://doaj.org/article/2d5dffc14b77467c9b8fce8043d1ab28