Effects of mineralocorticoid receptor overexpression on anxiety and memory after early life stress in female mice

Autor: Sofia eKanatsou, Judith P Ter Horst, Anjanette P Harris, Jonathan R Seckl, Harmen J Krugers, Marian eJoels

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 9 (2016)

Early-life stress is a risk factor for the development of psychopathology, particularly in women. Human studies have shown that certain haplotypes of NR3C2, encoding the mineralocorticoid receptor (MR), that result in gain of function, may protect ag

Externí odkaz: https://doaj.org/article/592d8db71a52466fa313e36d006d0122

Mineralocorticoid receptors guide spatial and stimulus-response learning in mice.

Autor: J Marit Arp, Judith P ter Horst, Sofia Kanatsou, Guillén Fernández, Marian Joëls, Harm J Krugers, Melly S Oitzl

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e86236 (2014)

Adrenal corticosteroid hormones act via mineralocorticoid (MR) and glucocorticoid receptors (GR) in the brain, influencing learning and memory. MRs have been implicated in the initial behavioral response in novel situations, which includes behavioral

Externí odkaz: https://doaj.org/article/aba0df5d950a464a861a26a4a227b355

Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

Autor: Carla S Verissimo, Rachel Elands, Sou Cheng, Dirk-Jan Saaltink, Judith P ter Horst, Maria N Alme, Chantal Pont, Bob van de Water, Bjarte Håvik, Carlos P Fitzsimons, Erno Vreugdenhil

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75752 (2013)

Doublecortin-like (DCL) is a microtubule-binding protein crucial for neuroblastoma (NB) cell proliferation. We have investigated whether the anti-proliferative effect of DCL knockdown is linked to reduced mitochondrial activity. We found a delay in t

Externí odkaz: https://doaj.org/article/7c3a58d47ee84c3e830b551ad871b99b

Kainate-induced epileptogenesis alters circular hole board learning strategy but not the performance of C57BL/6J mice

Autor: Rob A. Voskuyl, Geert J. Schenk, Pascale S. Kaptein, Judith P. ter Horst, Chantal J. Hubens

Publikováno v: Epilepsy & Behavior. 41:127-135

Patients with mesial temporal lobe epilepsy (mTLE) frequently show cognitive deficits. However, the relation between mTLE and cognitive impairment is poorly understood. To gain more insight into epilepsy-associated alterations in cognitive performanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c4ce0edb3aa2f3e44d93337b520838
https://doi.org/10.1016/j.yebeh.2014.09.038

Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice

Autor: Harmen J. Krugers, Sofia Kanatsou, Jonathan R. Seckl, Marian Joëls, Anjanette P. Harris, Judith P. ter Horst

Publikováno v: Frontiers in Behavioral Neuroscience, 9:374. Frontiers Media S.A.
Frontiers in Behavioral Neuroscience, Vol 9 (2016)
Frontiers in Behavioral Neuroscience
Kanatsou, S, Ter Horst, J P, Harris, A P, Seckl, J R, Krugers, H J & Joëls, M 2016, ' Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice ', Frontiers in Behavioral Neuroscience, vol. 9, pp. 374 . https://doi.org/10.3389/fnbeh.2015.00374
Frontiers in Behavioral Neuroscience [E], 9(374). Frontiers Research Foundation

Early-life stress is a risk factor for the development of psychopathology, particularly in women. Human studies have shown that certain haplotypes of NR3C2, encoding the mineralocorticoid receptor (MR), that result in gain of function, may protect ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb4bf6424aa27b5efa53b492cb3e37b
https://dare.uva.nl/personal/pure/en/publications/effects-of-mineralocorticoid-receptor-overexpression-on-anxiety-and-memory-after-early-life-stress-in-female-mice(4996205a-bc23-44f5-9ef5-2d26814fe628).html