Výsledky vyhledávání - "Judith Olzhausen"

Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene and engineering of the coenzyme A biosynthetic pathway

Autor: Judith Olzhausen, Hans-Joachim Schüller, Tom Ulbricht, Mathias Grigat, Larissa Seifert

Publikováno v: Applied Microbiology and Biotechnology

Coenzyme A (CoA) and its derivatives such as acetyl-CoA are essential metabolites for several biosynthetic reactions. In the yeast S. cerevisiae, five enzymes (encoded by essential genes CAB1-CAB5; coenzyme A biosynthesis) are required to perform CoA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b7387811eebe46e1ca0288e0319366
https://doi.org/10.1007/s00253-021-11523-4

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Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene

Autor: Seifert L, Mathias Grigat, Ulbricht T, Schueller H, Judith Olzhausen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af3988013c88562666578f9fa8628562
https://doi.org/10.1101/2021.05.25.445608

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An allergen-fused dendritic cell-binding peptide enhances in vitro proliferation of equine T-cells and cytokine production

Autor: Eman Hamza, Anja Ziegler, Claudio Rhyner, Ana Stojiljkovic, Mattia Garbani, Michael Hubert Stoffel, Eliane Isabelle Marti, Judith Olzhausen

Publikováno v: Veterinary Immunology and Immunopathology. 243:110351

Allergen-specific immunotherapy (AIT) constitutes the only curative approach for allergy treatment. There is need for improvement of AIT in veterinary medicine, such as in horses suffering from insect bite hypersensitivity, an IgE-mediated dermatitis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb0b2e2dbdd1e69f995ebd4b0c6ca0c
https://doi.org/10.1016/j.vetimm.2021.110351

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Interleukins (from IL-1 to IL-38), interferons, transforming growth factor b, and TNF-a : Receptors, functions, and roles in diseases

Publikováno v: J. Allergy Clin Immunol

There have been extensive developments on cellular and molecular mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumor development, organ transplantation, and chronic infections during the last few years. Better understanding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ca8adf7aa63f15d7045817ed7b9a8e
https://doi.org/10.1016/j.jaci.2016.06.033

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Novel in vitro diagnosis of equine allergies using a protein array and mathematical modelling approach: a proof of concept using insect bite hypersensitivity

Autor: Grazziela P. Figueredo, Judith Olzhausen, Xiaowei Wang, Eliane Isabelle Marti, Claudio Rhyner, Nuzul Noorahya Jambari, Marcos J. C. Alcocer, José Javier Pérez-Barea

Publikováno v: IndraStra Global.

Insect bite hypersensitivity (IBH) is a seasonal recurrent skin allergy of horses caused by IgE-mediated reactions to allergens present in the saliva of biting insects of the genus Culicoides, and possibly also Simulium and Stomoxys species. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cffbef348d2602f3754e6688124c8b2
https://igi.indrastra.com/items/show/19889

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Molecular characterization of the heteromeric coenzyme A-synthesizing protein complex (CoA-SPC) in the yeast Saccharomyces cerevisiae

Autor: Tom Moritz, Judith Olzhausen, Tim Neetz, Hans-Joachim Schüller

Publikováno v: FEMS yeast research. 13(6)

Coenzyme A (CoA) as an essential cofactor for acyl and acetyl transfer reactions is synthesized in five enzymatic steps from pantothenate, cysteine, and ATP. In the yeast Saccharomyces cerevisiae, products of five essential genes CAB1-CAB5 (coenzyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f222968b097cfac732096ed03d1369c
https://pubmed.ncbi.nlm.nih.gov/23789928

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Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1

Autor: Judith Olzhausen, Sabrina Schübbe, Hans-Joachim Schüller

Publikováno v: Current genetics. 55(2)

Coenzyme A (CoA) is a ubiquitous cofactor required for numerous enzymatic carbon group transfer reactions. CoA biosynthesis requires contributions from various amino acids with pantothenate as an important intermediate which can be imported from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efe2c1e36496b235865b4d6287a9e93
https://pubmed.ncbi.nlm.nih.gov/19266201

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