Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Judith Molina-David"'
Autor:
Alla Mitrofanova, Antonio Fontanella, Matthew Tolerico, Shamroop Mallela, Judith Molina David, Yiqin Zuo, Marcia Boulina, Jin-Ju Kim, Javier Santos, Mengyuan Ge, Alexis Sloan, Wadih Issa, Margaret Gurumani, Jeffrey Pressly, Marie Ito, Matthias Kretzler, Sean Eddy, Robert Nelson, Sandra Merscher, George Burke, Alessia Fornoni
Publikováno v:
Journal of the American Society of Nephrology. 33:2153-2173
The signaling molecule stimulator of IFN genes (STING) was identified as a crucial regulator of the DNA-sensing cyclic GMP-AMP synthase (cGAS)-STING pathway, and this signaling pathway regulates inflammation and energy homeostasis under conditions of
Autor:
Bernd Kuhn, Franziska Weibel, Rodolfo Gasser, Marco Prunotto, Solange Moll, Martine Stihle, R. Daniel Bonfil, Bernard Gsell, Christian Faul, Remo Hochstrasser, Sabine Uhles, Guy Georges, Ann C. Petersen, Javier Varona Santos, Ricardo Hermosilla, Alexander L. Satz, Hans Richter, Rafael Fridman, Marc Bedoucha, Markus G. Rudolph, Bernd Buettelmann, Anja Harmeier, Martin Ritter, Melanie N. Hug, Alessia Fornoni, Judith Molina-David, Jin Ju Kim, Sylwia Huber, Buelent Kocer, Dominique Burger
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, Vol. 14, No 1 (2019) pp. 37-49
ACS Chemical Biology, Vol. 14, No 1 (2019) pp. 37-49
The importance of Discoidin Domain Receptor 1 (DDR1) in renal fibrosis has been shown via gene knockout and use of antisense oligonucleotides; however, these techniques act via a reduction of DDR1 protein, while we prove the therapeutic potential of
Autor:
Judith Molina-David, Gian Marco Ghiggeri, Gloria Michelle Ducasa, Mengyuan Ge, Sandra Merscher, Oliver Kretz, Sean Eddy, Farah Leclercq, George W. Burke, Tahreem Hashmi, Sebastian Martini, Heather N. Reich, Tobias B. Huber, Carol Forsblom, Alexis Sloan, Christopher E. Pedigo, Markku Lehto, Per-Henrik Groop, Christian Faul, Matthias Kretzler, Mariann I. Lassenius, Patricia Wahl, Alessia Fornoni, Alla Mitrofanova, Armando J. Mendez
Publikováno v:
The Journal of clinical investigation. 126(9)
High levels of circulating TNF and its receptors, TNFR1 and TNFR2, predict the progression of diabetic kidney disease (DKD), but their contribution to organ damage in DKD remains largely unknown. Here, we investigated the function of local and system