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pro vyhledávání: '"Judith Menth"'
Publikováno v:
AAPS PharmSciTech. 23(1)
Starting point of the presented study were abrasion effects occurring during a twin screw wet granulation (TSG) process of a new chemical entity (NCE) formulation, resulting in gray spots on the final tablets. Several actions and systematic changes o
Autor:
Robert Schmidtke, Karl G. Wagner, Andrea Staab, Daniela Schröder, Michael Braun, Judith Menth
Publikováno v:
International Journal of Pharmaceutics. 523:366-375
The aim of this study was to provide a systematic evaluation of various compression models (Percolation, Kawakita, Exponential model) in respect to predict tablet́s solid fraction for direct compression mixtures, based on single component compressio
Publikováno v:
International Journal of Pharmaceutics. 586:119509
This study provides the results of investigation on scaling approaches for three differently-sized continuous granulation lines, each consisting of a twin screw wet granulation process and a continuous fluid bed drying process. To check the initial s