Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Judith M. Bergeron"'
Autor:
Jiyong Liang, Jinhee Kim, Kevin D. Houston, Jianjun Shen, John D. Short, Gordon B. Mills, Sheng Li Cai, Mark T. Bedford, Cheryl L. Walker, Judith M. Bergeron, Ruhee Dere
Publikováno v:
Molecular Carcinogenesis. 49:429-439
The tuberous sclerosis complex 2 (Tsc2) gene product, tuberin, acts as a negative regulator of mTOR signaling, and loss of tuberin function leads to tumors of the brain, skin, kidney, heart, and lungs. Previous studies have shown that loss of tuberin
Publikováno v:
Environmental Toxicology and Chemistry. 21:2477-2482
Polyhalogenated hydrocarbons have been implicated in the anomalous sexual differentiation of mammals and reptiles. Here, a temperature-sensitive turtle sex determination assay using the red-eared slider (Trachemys scripta elegans) was used to determi
Publikováno v:
Environmental Health Perspectives
Gonadal sex in the red-eared slider turtle, Trachemys scripta, is determined by incubation temperature during embryonic development. Evidence suggests that temperature determines sex by influencing steroid hormone metabolism and/or sensitivity: stero
Autor:
Steven F. Arnold, William A. Toscano, Dat Q. Tran, Judith M. Bergeron, Peter M. Vonier, David Crews, John A. McLachlan, Bridgette M. Collins
Publikováno v:
Biochemical and Biophysical Research Communications. 235:336-342
Many environmental agents exert estrogenic activity. Previous studies from our laboratories demonstrated that certain combinations of environmental estrogens (i) reverse the sex of male turtle embryos in a synergistic manner (Bergeron et al., (1994)
Publikováno v:
Journal of Endocrinology. 149:457-463
This study addressed the hypothesis that, in the red-eared slider turtle, Trachemys scripta, non-aromatizable androgens are the physiological equivalent of temperature in determining male development. In the first experiment, eggs were treated in the
Publikováno v:
General and Comparative Endocrinology. 100:119-127
In many turtles the temperature during the middle of incubation determines the gonadal sex of the hatchling. Sex steroid hormones have been implicated in temperature-dependent sex determination in the red-eared slider turtle, Trachemys scripta ; andr
Publikováno v:
Proceedings of the National Academy of Sciences. 90:7172-7175
An isoform of the estrogen receptor messenger RNA (ER-mRNA) was identified in RNA from the brain of lizards and rats. Poly(A)+ RNA from brain and uteri was reverse transcribed using gene-specific primer for the ER. The resulting complementary DNA was
Autor:
John D, Short, Ruhee, Dere, Kevin D, Houston, Sheng-Li, Cai, Jinhee, Kim, Judith M, Bergeron, Jianjun, Shen, Jiyong, Liang, Mark T, Bedford, Gordon B, Mills, Cheryl Lyn, Walker
Publikováno v:
Molecular carcinogenesis. 49(5)
The tuberous sclerosis complex 2 (Tsc2) gene product, tuberin, acts as a negative regulator of mTOR signaling, and loss of tuberin function leads to tumors of the brain, skin, kidney, heart, and lungs. Previous studies have shown that loss of tuberin
Autor:
Charles L. Johnson, Jinhee Kim, Ruifeng Guo, Jianjun Shen, Kaoru Kiguchi, Judith M. Bergeron, Cheryl L. Walker, Johnny D Short, Andrew R. Tee, Sheng Li Cai
Publikováno v:
The Journal of Cell Biology
Loss of tuberin, the product of TSC2 gene, increases mammalian target of rapamycin (mTOR) signaling, promoting cell growth and tumor development. However, in cells expressing tuberin, it is not known how repression of mTOR signaling is relieved to ac
Publikováno v:
Environmental toxicology and chemistry. 21(11)
Polyhalogenated hydrocarbons have been implicated in the anomalous sexual differentiation of mammals and reptiles. Here, a temperature-sensitive turtle sex determination assay using the red-eared slider (Trachemys scripta elegans) was used to determi