Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Judith L. Black"'
Autor:
Brian G. Oliver, Judith L. Black
Publikováno v:
Allergology International, Vol 55, Iss 3, Pp 215-223 (2006)
The airway smooth muscle is the key determinant of airway narrowing in asthma but its function in the absence of disease is unknown. Evidence for an intrinsic abnormality in the muscle in asthma is only just emerging. The airway smooth muscle is not
Externí odkaz:
https://doaj.org/article/48d9b91c534c41ec82985aa310bcde4c
Autor:
Alen Faiz, Gavin Tjin, Louise Harkness, Markus Weckmann, Shisan Bao, Judith L. Black, Brian G. G. Oliver, Janette K. Burgess
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/488cc069a6f24a5c91a592afeb1961f9
Autor:
Karryn T Grafton, Lyn M Moir, Judith L Black, Nicole G Hansbro, Philip M Hansbro, Janette K Burgess, Brian G Oliver
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85655 (2014)
BackgroundTumstatin is a segment of the collagen-IV protein that is markedly reduced in the airways of asthmatics. Tumstatin can play an important role in the development of airway remodelling associated with asthma due to its anti-angiogenic propert
Externí odkaz:
https://doaj.org/article/059d0ec733d9435892adfc513cf752be
Autor:
Nessa Banville, Janette K Burgess, Jade Jaffar, Gavin Tjin, Luca Richeldi, Stefania Cerri, Elisa Persiani, Judith L Black, Brian G Oliver
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105365 (2014)
Lymphangioleiomyomatosis (LAM) is a rare and progressive cystic lung condition affecting approximately 3.4-7.5/million women, with an average lag time between symptom onset and diagnosis of upwards of 4 years. The aim of this work was to identify alt
Externí odkaz:
https://doaj.org/article/4af9af2ec73e45d08c84b37b0e264465
Autor:
David Van Ly, Alen Faiz, Christine Jenkins, Ben Crossett, Judith L Black, Brent McParland, Janette K Burgess, Brian G G Oliver
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56058 (2013)
Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β2 agonist therapy. Using an in vitro model of RV infection, we investigated the mechanisms underly
Externí odkaz:
https://doaj.org/article/0b7931eb10c44f7d82117f181d73dadd
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65544 (2013)
Fibulin-1 (FBLN-1) is a secreted glycoprotein that is associated with extracellular matrix (ECM) formation and rebuilding. Abnormal and exaggerated deposition of ECM proteins is a hallmark of many fibrotic diseases, such as chronic obstructive pulmon
Externí odkaz:
https://doaj.org/article/c676cf90d28b4c5ea686dcd152ddcea5
Autor:
Alen Faiz, Gavin Tjin, Louise Harkness, Markus Weckmann, Shisan Bao, Judith L Black, Brian G G Oliver, Janette K Burgess
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57245 (2013)
Tumstatin is an anti-angiogenic collagen IV α3 fragment, levels of which are reduced in the airways of asthmatics. Its reduction may be due to the degradation by extracellular matrix (ECM) proteases. Cathepsins play a role in ECM remodelling, with c
Externí odkaz:
https://doaj.org/article/773520963db848a391ec73e7b1113f90
Autor:
Justine Y Lau, Brian G Oliver, Melissa Baraket, Emma L Beckett, Nicole G Hansbro, Lyn M Moir, Steve D Wilton, Carolyn Williams, Paul S Foster, Philip M Hansbro, Judith L Black, Janette K Burgess
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13360 (2010)
BACKGROUND: The extracellular matrix is a dynamic and complex network of macromolecules responsible for maintaining and influencing cellular functions of the airway. The role of fibronectin, an extracellular matrix protein, is well documented in asth
Externí odkaz:
https://doaj.org/article/ddc794eb15104c2bb96d4b448d663262
Autor:
Corneel J Vermeulen, Janette K. Burgess, Mehra Haghi, Haitatip Tasena, Markus Weckmann, Gavin Tjin, Gregory G. King, Claude S. Farah, Irene H. Heijink, Cheng-Jian Xu, Maarten van den Berge, Brian G. Oliver, Nick H. T. ten Hacken, Jeremy P.T. Ward, Tak H. Lee, Judith L. Black, Alen Faiz, Andrew J. Halayko
Publikováno v:
European Respiratory Journal, 52(2):1800310. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Chronic mucus hypersecretion (CMH) contributes to the morbidity and mortality of asthma, and remains uncontrolled by current therapies in the subset of patients with severe, steroidresistant disease. Altered cross-talk between airway epithelium and a
Autor:
Caroline A. Heckman, Judith L. Black, Lyn M. Moir, Brian G. Oliver, Janette K. Burgess, Markus Weckmann
Publikováno v:
Journal of Cellular and Molecular Medicine
The lymphatic system is essential for the maintenance of tissue homeostasis and immunity. Its dysfunction in disease (such as lymphangioleiomyomatosis) can lead to chylous effusions, oedema or dissemination of malignant cells. Collagen IV has six α