Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Judith Krall"'
Autor:
Faiyaz Ahmad, Eva Degerman, Matthew A. Movsesian, Frank Goetz, Enno Klussmann, Fabrice Vandeput, Weixing Shen, Vincent C. Manganiello, Nicolas Szabo-Fresnais, Judith Krall
Publikováno v:
Journal of Biological Chemistry. 290:6763-6776
Cyclic nucleotide phosphodiesterase 3A (PDE3) regulates cAMP-mediated signaling in the heart, and PDE3 inhibitors augment contractility in patients with heart failure. Studies in mice showed that PDE3A, not PDE3B, is the subfamily responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e449826ce2c0d6ebf3b19a5a192a9c
https://doi.org/10.1074/jbc.m115.638585
https://doi.org/10.1074/jbc.m115.638585
Autor:
Nicolas Szabo-Fresnais, Faiyaz Ahmad, Roger J. Hajjar, Changwon Kho, Mark Hazel, Fabrice Vandeput, Matthew A. Movsesian, Judith Krall, Allan J. Dunlop, Miles D. Houslay, James A. Wohlschlegel, Vincent C. Manganiello, Ahyoung Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 110:19778-19783
Inhibitors of cyclic nucleotide phosphodiesterase (PDE) PDE3A have inotropic actions in human myocardium, but their long-term use increases mortality in patients with heart failure. Two isoforms in cardiac myocytes, PDE3A1 and PDE3A2, have identical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daeb8abfda84511fc531ab4da5d786b
https://doi.org/10.1073/pnas.1305427110
https://doi.org/10.1073/pnas.1305427110
Autor:
Matthew A. Movsesian, Judith Krall, Vincent A. Florio, Rakesh C. Kukreja, Fabrice Vandeput, Fadi N Salloum, Ramzi A Ockaili, Sharron H. Francis, Jackie D. Corbin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 330:884-891
In mouse models of cardiac disease, the type 5 (PDE5)-selective cyclic nucleotide phosphodiesterase inhibitor sildenafil has antihypertrophic and cardioprotective effects attributable to the inhibition of cGMP hydrolysis. To investigate the relevance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43bf9519d6acda2d35649f2a5a0b36a
https://doi.org/10.1124/jpet.109.154468
https://doi.org/10.1124/jpet.109.154468
Autor:
Judith Krall, Marina Freudzon, Rachael P. Norris, Lisa M. Mehlmann, Laurinda A. Jaffe, William J. Ratzan, Huanchen Wang, Viacheslav O. Nikolaev, Hengming Ke, Matthew A. Movsesian
Publikováno v:
Development. 136:1869-1878
Mammalian oocytes are arrested in meiotic prophase by an inhibitory signal from the surrounding somatic cells in the ovarian follicle. In response to luteinizing hormone (LH), which binds to receptors on the somatic cells, the oocyte proceeds to seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45a05f061a8b3073da3f33f73e7f4e3
https://doi.org/10.1242/dev.035238
https://doi.org/10.1242/dev.035238
Autor:
Enno Klussmann, Judith Krall, Vincent C. Manganiello, Nicolas Szabo-Fresnais, Eva Degerman, Frank Goetz, Faiyaz Ahmad, Weixing Shen, Fabrice Vandeput, Matthew A. Movsesian
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200aeb9bf4480bd936c26fbc5208ca2a
https://doi.org/10.1096/fasebj.29.1_supplement.728.24
https://doi.org/10.1096/fasebj.29.1_supplement.728.24
Autor:
Leonardo Furlan, Stuart A. Nicklin, Frank Gesellchen, Laura Ashley Fields, Ivar Sjaastad, Graham Hamilton, Judith Krall, Matthew A. Movsesian, Giuliano Dodoni, Luisa Mancuso, Manuela Zaccolo, Jan Magnus Aronsen, Craig Livie, Konstantinos Lefkimmiatis, Alessandra Stangherlin, Fabrice Vandeput, Nicolas Szabo-Fresnais, Anna Zoccarato, Yuan Yan Sin, Anna Terrin, Nicoletta C. Surdo, Veronica Corsetti, Delyth Graham, George S. Baillie, He Jiang
Publikováno v:
Circulation research. 117(8)
Rationale : Chronic elevation of 3′-5′-cyclic adenosine monophosphate (cAMP) levels has been associated with cardiac remodeling and cardiac hypertrophy. However, enhancement of particular aspects of cAMP/protein kinase A signaling seems to be ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97658dd4c46b3d9c9366fedfeaece51
https://pubmed.ncbi.nlm.nih.gov/26243800
https://pubmed.ncbi.nlm.nih.gov/26243800
Autor:
Judith Krall, Jeremy Wechsler, Vincent C. Manganiello, Faiyaz Ahmad, Matthew A. Movsesian, Young Hun Choi
Publikováno v:
Journal of Biological Chemistry. 277:38072-38078
PDE3A cyclic nucleotide phosphodiesterases regulate cAMP- and cGMP-mediated intracellular signaling in cardiac myocytes. We used antibodies to different regions of PDE3A to demonstrate the presence of three PDE3A isoforms in these cells. These isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934c1593e3fcb46e6bb298085de75bbe
https://doi.org/10.1074/jbc.m203647200
https://doi.org/10.1074/jbc.m203647200
Autor:
Nicolas Szabo-Fresnais, Vincent C. Manganiello, Roger J. Hajjar, Matthew A. Movsesian, Judith Krall, Fabrice Vandeput, Changwon Kho, Faiyaz Ahmad, Ahyoung Lee
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dba46bf40f47366dcc3809f9e01da36
https://doi.org/10.1096/fasebj.28.1_supplement.1013.23
https://doi.org/10.1096/fasebj.28.1_supplement.1013.23
Autor:
Judith Krall, Faiyaz Ahmad, Matthew A. Movsesian, Young Hun Choi, Vincent C. Manganiello, Dag Ekholm, Eva Degerman
Publikováno v:
Biochemical Journal. 353:41-50
We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its coding region is similar to that of the previously cloned myocardial isoform except for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8ec36a0ce89be14e3c8586bb1183873
https://doi.org/10.1042/bj3530041
https://doi.org/10.1042/bj3530041
Autor:
Judith Krall, Matthew A. Movsesian, Allan J. Dunlop, Vincent C. Manganiello, Nicolas Szabo-Fresnais, Fabrice Vandeput, Miles D. Houslay
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a858e8bab6004e1ad02543b6a328d783
https://doi.org/10.1096/fasebj.27.1_supplement.1052.3
https://doi.org/10.1096/fasebj.27.1_supplement.1052.3