A Data Mining Metabolomics Exploration of Glaucoma

Autor: Judith Kouassi Nzoughet, Khadidja Guehlouz, Stéphanie Leruez, Philippe Gohier, Cinzia Bocca, Jeanne Muller, Odile Blanchet, Dominique Bonneau, Gilles Simard, Dan Milea, Vincent Procaccio, Guy Lenaers, Juan M. Chao de la Barca, Pascal Reynier

Publikováno v: Metabolites, Vol 10, Iss 2, p 49 (2020)

Glaucoma is an age related disease characterized by the progressive loss of retinal ganglion cells, which are the neurons that transduce the visual information from the retina to the brain. It is the leading cause of irreversible blindness worldwide.

Externí odkaz: https://doaj.org/article/02a78fb57d544fff9e210b2415b08086

Data from Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor Phenotype

Autor: Pascale Jeannin, Yves Delneste, Vincent Procaccio, Judith Kouassi Nzoughet, Cinzia Bocca, Guy Lenaers, Guillaume Tcherkez, Véronique Catros, Alain Morel, Philippe Descamps, Vincent Lavoué, Norbert Ifrah, Pedro Raro, Véronique Verrielle, Romuald Wernert, Mario Campone, Louise-Marie Chevalier, Valérie Seegers, Pascale Pignon, Simon Blanchard, Laurence Preisser, Céline Beauvillain, Clément Adam, Léa Paolini

In established tumors, tumor-associated macrophages (TAM) orchestrate nonresolving cancer-related inflammation and produce mediators favoring tumor growth, metastasis, and angiogenesis. However, the factors conferring inflammatory and protumor proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc98ea1e4b27f88d776718a965df5759
https://doi.org/10.1158/2326-6066.c.6550239

Lipidomics Reveals Triacylglycerol Accumulation Due to Impaired Fatty Acid Flux in Opa1-Disrupted Fibroblasts

Autor: Dominique Bonneau, Charlotte Veyrat-Durebex, Arnaud Chevrollier, Stéphanie Chupin, Gilles Simard, Guy Lenaers, Judith Kouassi Nzoughet, Cinzia Bocca, Mariame Selma Kane, Pascal Reynier, Juan Manuel Chao de la Barca, Vincent Procaccio, Jennifer Alban

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2019, 18 (7), pp.2779-2790. ⟨10.1021/acs.jproteome.9b00081⟩

OPA1 is a dynamin GTPase implicated in mitochondrial membrane fusion. Despite its involvement in lipid remodeling, the function of OPA1 has never been analyzed by whole-cell lipidomics. We used a nontargeted, reversed-phase lipidomics approach, valid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa82e6a15c26b95a0a9f4e0d2844fa18
https://doi.org/10.1021/acs.jproteome.9b00081

Lactic acidosis together with GM-CSF and M-CSF induces human macrophages toward an inflammatory pro-tumor phenotype

Autor: Laurence Preisser, Pedro Raro, Clément Adam, Pascale Pignon, Vincent Procaccio, Vincent Lavoué, Alain Morel, Philippe Descamps, Simon Blanchard, Cinzia Bocca, Valérie Seegers, Céline Beauvillain, Romuald Wernert, Judith Kouassi Nzoughet, Léa Paolini, Norbert Ifrah, Pascale Jeannin, Véronique Verrielle, Yves Delneste, Mario Campone, Véronique Catros, Louise-Marie Chevalier, Guy Lenaers, Guillaume Tcherkez

Publikováno v: Cancer Immunology Research
Cancer Immunology Research, American Association for Cancer Research, 2020, 8 (3), pp.383-395. ⟨10.1158/2326-6066.CIR-18-0749⟩
Cancer Immunology Research, 2020, 8 (3), pp.383-395. ⟨10.1158/2326-6066.cir-18-0749⟩
Cancer Immunology Research, 2020, 8 (3), pp.383-395. ⟨10.1158/2326-6066.CIR-18-0749⟩
Cancer Immunology Research, American Association for Cancer Research, 2020, 8 (3), pp.383-395. ⟨10.1158/2326-6066.cir-18-0749⟩

In established tumors, tumor-associated macrophages (TAM) orchestrate nonresolving cancer-related inflammation and produce mediators favoring tumor growth, metastasis, and angiogenesis. However, the factors conferring inflammatory and protumor proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01f977c9d17941494e49abd45970ae5
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02442525

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