Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Judith K Gwathmey"'
Autor:
Abderrazak Kitsy, Skyla Carney, Juan C Vivar, Megan S Knight, Mildred A Pointer, Judith K Gwathmey, Sujoy Ghosh
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102615 (2014)
The essential branched-chain amino acids (BCAA), leucine, valine and isoleucine, are traditionally associated with skeletal muscle growth and maintenance, energy production, and generation of neurotransmitter and gluconeogenic precursors. Recent evid
Externí odkaz:
https://doaj.org/article/046ff3b4c6bc4c05a91d46f225b25fee
Autor:
Chanon Piamsiri, Nadezhda Fefelova, Sri Harika Pamarthi, Judith K. Gwathmey, Siriporn C. Chattipakorn, Nipon Chattipakorn, Lai-Hua Xie
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1334 (2024)
Inositol 1,4,5-trisphosphate receptors (IP3Rs) play a crucial role in maintaining intracellular/cytosolic calcium ion (Ca2+i) homeostasis. The release of Ca2+ from IP3Rs serves as a second messenger and a modulatory factor influencing various intrace
Externí odkaz:
https://doaj.org/article/81037d2c369047bebc4842442759b1e6
Autor:
Zhenghang eZhao, Hairuo eWen, Nadezhda eFefelova, Charelle eAllen, Nancy eGuillaume, Dandan eXiao, Chen eHuang, Wei-Jin eZang, Judith K Gwathmey, Lai-Hua eXie
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Accumulating evidence has suggested that ω3-polyunsaturated fatty acids (ω3-PUFAs) may have beneficial effects in the prevention/treatment of cardiovascular diseases, while controversies still remain regarding their antiarrhythmic potential. It is
Externí odkaz:
https://doaj.org/article/eb030197413f4e3e8bce0817337299ce
Publikováno v:
Cells, Vol 11, Iss 17, p 2726 (2022)
Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell death characterized by iron-dependence and the accumulation of lipid peroxidation that results in membrane damage. Excessive iron induces ferroptosis by promoting t
Externí odkaz:
https://doaj.org/article/a1ba2d4a38dd4da398b1ed1f0d375baf
Publikováno v:
Pflugers Arch
Hibernation allows animals to enter an energy conserving state to survive severe drops in external temperatures and a shortage of food. It has been observed that the heart of mammalian hibernators exhibits intrinsic protection against ischemia-reperf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3d82198439f838c3e3ab68340ac5c5
https://doi.org/10.1007/s00424-020-02511-0
https://doi.org/10.1007/s00424-020-02511-0
Publikováno v:
Circulation. 144
Background: Ferroptosis is a newly described form of non-apoptotic cell death caused by iron (Fe)-dependent lipid peroxidation. It remains unclear how different signaling pathways/molecules are involved in ferroptosis induction and prevention in card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad4dc4100b2496494f7f3879e433c3d
https://doi.org/10.1161/circ.144.suppl_1.11118
https://doi.org/10.1161/circ.144.suppl_1.11118
Autor:
Angelia A. Doye, Jazna Naushad, Lai-Hua Xie, Behzad Dadfar, Riya Jaleel, Natthaphat Siri-Angkul, Jaseela Parambathazhath, Judith K. Gwathmey
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7392, p 7392 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 7392, p 7392 (2021)
The occurrence and prevalence of heart failure remain high in the United States as well as globally. One person dies every 30 s from heart disease. Recognizing the importance of heart failure, clinicians and scientists have sought better therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31655babae4c7a336dfe41cdc0b33ada
https://pubmed.ncbi.nlm.nih.gov/34299010
https://pubmed.ncbi.nlm.nih.gov/34299010
Autor:
Zhen Song, Nipon Chattipakorn, Zhilin Qu, Siriporn C. Chattipakorn, Nadezhda Fefelova, Judith K. Gwathmey, Natthaphat Siri-Angkul, Lai-Hua Xie
Publikováno v:
Circ Arrhythm Electrophysiol
Background: Arrhythmias and heart failure are common cardiac complications leading to substantial morbidity and mortality in patients with hemochromatosis, yet mechanistic insights remain incomplete. We investigated the effects of iron (Fe) on electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a79d86fba37b48538c8a98909ab9ed7
https://doi.org/10.1161/circep.120.009291
https://doi.org/10.1161/circep.120.009291
Autor:
Natthaphat Siri-Angkul, Judith K. Gwathmey, Siriporn C. Chattipakorn, Lai-Hua Xie, Suwakon Wongjaikam, Nipon Chattipakorn, Nadezhda Fefelova
Publikováno v:
Circulation. 142
Iron (Fe) plays essential roles in many physiological processes. Hereditary hemochromatosis and frequent blood transfusions result in iron overload (IO) and dysfunction of iron-deposited organs including the heart. Although IO-induced cardiomyopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893a7ae0d1f25483ff987e850e4ae251
https://doi.org/10.1161/circ.142.suppl_3.15737
https://doi.org/10.1161/circ.142.suppl_3.15737
Publikováno v:
Nutrition and Health ISBN: 9781003068822
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0926aefd12024133e92385ad8b5fa4dd
https://doi.org/10.1201/9781003068822-6
https://doi.org/10.1201/9781003068822-6
