Real-world considerations for the rapid prototyping and manufacture of a ventilator for the COVID-19 pandemic

Autor: Judith Ju Ming Wong, Fiona Wei Ling Loke, Herng Lee Tan, Jessica Lishan Quah, Wai Chye Cheong, Shariq Ali Khan, Biju Thomas, Ghee Chee Phua, Derrick Wei Shih Chan

Publikováno v: Proceedings of Singapore Healthcare, Vol 32 (2023)

Background In the COVID-19 pandemic, ventilators vital to keeping infected patients alive, were in short supply globally. Our aim was to rapidly prototype and implement production of basic ventilators to serve the local and regional needs in this eme

Externí odkaz: https://doaj.org/article/61d358a5318c4385bfd5075346f2cc48

Large scale cytokine profiling uncovers elevated IL12-p70 and IL-17A in severe pediatric acute respiratory distress syndrome

Autor: Judith Ju Ming Wong, Herng Lee Tan, Jieliang Zhou, Jan Hau Lee, Jing Yao Leong, Joo Guan Yeo, Yie Hou Lee

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract The specific cytokines that regulate pediatric acute respiratory distress syndrome (PARDS) pathophysiology remains unclear. Here, we evaluated the respiratory cytokine profile in PARDS to identify the molecular signatures associated with sev

Externí odkaz: https://doaj.org/article/823f3e2843cb4bb1923fd90646dd85e9

Development and validation of a clinical predictive model for severe and critical pediatric COVID-19 infection.

Autor: Judith Ju Ming Wong, Qalab Abbas, Felix Liauw, Ririe Fachrina Malisie, Chin Seng Gan, Muhammad Abid, Pustika Efar, Josephine Gloriana, Soo Lin Chuah, Rehena Sultana, Koh Cheng Thoon, Chee Fu Yung, Jan Hau Lee, PACCOVRA Investigators of the PACCMAN research group

Publikováno v: PLoS ONE, Vol 17, Iss 10, p e0275761 (2022)

IntroductionChildren infected with COVID-19 are susceptible to severe manifestations. We aimed to develop and validate a predictive model for severe/ critical pediatric COVID-19 infection utilizing routinely available hospital level data to ascertain

Externí odkaz: https://doaj.org/article/427fa6296c82467fb8547b4a3020006a

Operational definitions related to pediatric ventilator liberation

Autor: Samer Abu-Sultaneh, Narayan Prabhu Iyer, Analía Fernández, Michael Gaies, Sebastián González-Dambrauskas, Justin Christian Hotz, Martin C.J. Kneyber, Yolanda M. López-Fernández, Alexandre T. Rotta, David K. Werho, Arun Kumar Baranwal, Bronagh Blackwood, Hannah J. Craven, Martha A.Q. Curley, Sandrine Essouri, Jose Roberto Fioretto, Silvia M.M. Hartmann, Philippe Jouvet, Steven Kwasi Korang, Gerrard F. Rafferty, Padmanabhan Ramnarayan, Louise Rose, Lyvonne N. Tume, Elizabeth C. Whipple, Judith Ju Ming Wong, Guillaume Emeriaud, Christopher W. Mastropietro, Natalie Napolitano, Christopher J.L. Newth, Robinder G. Khemani

Publikováno v: Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Abu-Sultaneh, S, Iyer, N P, Fernández, A, Gaies, M, González-Dambrauskas, S, Hotz, J C, Kneyber, M C J, López-Fernández, Y M, Rotta, A T, Werho, D K, Baranwal, A K, Blackwood, B, Craven, H J, Curley, M A Q, Essouri, S, Fioretto, J R, Hartmann, S M, Jouvet, P, Korang, S K, Rafferty, G F, Ramnarayan, P, Rose, L, Tume, L N, Whipple, E C, Wong, J J M, Emeriaud, G, Mastropietro, C W, Napolitano, N, Newth, C J L & Khemani, R G 2023, ' Operational definitions related to pediatric ventilator liberation ', Chest, vol. 163, no. 5, pp. 1130-1143 . https://doi.org/10.1016/j.chest.2022.12.010

BACKGROUND: Common, operational definitions are crucial to assess interventions and outcomes related to pediatric mechanical ventilation. These definitions can reduce unnecessary variability amongst research and quality improvement efforts, to ensure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddc30d72576374ee3da0e85b100dee4
https://pure.qub.ac.uk/en/publications/646cb9e1-aac6-4758-bc46-7b88073efcab

Pediatric COVID-19 Risk Factors in Southeast Asia-Singapore and Malaysia: A Test-Negative Case–Control Study

Autor: Judith Ju Ming Wong, Chin Seng Gan, Sanghvi Heli Kaushal, Soo Lin Chuah, Rehena Sultana, Natalie Woon Hui Tan, Kah Peng Eg, Koh Cheng Thoon, Jan Hau Lee, Chee Fu Yung

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 106:1113-1120

There is a scarcity of population-level data of pediatric COVID-19 infection from Southeast Asia. This study aims to describe and compare epidemiological, clinical, laboratory and outcome data among pediatric COVID-19 cases versus controls in two nei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b51d9208ddfc3f43f00e65e28e1a2f
https://doi.org/10.4269/ajtmh.21-1000