Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Judith J. Eckert"'
Autor:
Pooja Khurana, Andrew Cox, Barira Islam, Judith J. Eckert, Sandrine Willaime-Morawek, Joanna M. Gould, Neil R. Smyth, Patrick C. McHugh, Tom P. Fleming
Publikováno v:
Stem Cell Reviews and Reports. 19:767-783
Peri-conceptional environment can induce permanent changes in embryo phenotype which alter development and associate with later disease susceptibility. Thus, mouse maternal low protein diet (LPD) fed exclusively during preimplantation is sufficient t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fa2c261a6af2e28b5bda55e13a4349
https://doi.org/10.1007/s12015-022-10490-1
https://doi.org/10.1007/s12015-022-10490-1
Autor:
Neil Smyth, Judith J. Eckert, Miguel A. Velazquez, Bhavwanti Sheth, Tom P. Fleming, Pooja Khurana
Publikováno v:
Journal of Developmental Origins of Health and Disease. 13:395-405
Advanced maternal age (AMA) is known to reduce fertility, increases aneuploidy in oocytes and early embryos and leads to adverse developmental consequences which may associate with offspring lifetime health risks. However, investigating underlying ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc7c0eab42e2ad4fa9fc2f47304878f
https://doi.org/10.1017/s2040174421000325
https://doi.org/10.1017/s2040174421000325
Autor:
Reyna S Penailillo, M A Burton, Graham C. Burdge, Karen A. Lillycrop, Judith J. Eckert, Tom P. Fleming
Publikováno v:
Molecular Reproduction and Development. 88:261-273
Folate, a cofactor for the supply of one-carbon groups, is required by epigenetic processes to regulate cell lineage determination during development. The intake of folic acid (FA), the synthetic form of folate, has increased significantly over the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3006202f17fb60fe83137accff9973b5
https://doi.org/10.1002/mrd.23462
https://doi.org/10.1002/mrd.23462
Autor:
Richard O.C. Oreffo, Adam J. Watkins, Judith J. Eckert, Emma S. Lucas, Niamh MacCaoilte, Stephanie J. Smith, Tom P. Fleming, Stuart A. Lanham
Publikováno v:
Journal of Developmental Origins of Health and Disease. 12:384-395
Adverse programming of adult non-communicable disease can be induced by poor maternal nutrition during pregnancy and the periconception period has been identified as a vulnerable period. In the current study, we used a mouse maternal low-protein diet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a901344a932d2483024106827df098ca
https://doi.org/10.1017/s204017442000046x
https://doi.org/10.1017/s204017442000046x
Autor:
Judith J Eckert, Richard Porter, Adam J Watkins, Elizabeth Burt, Suzanne Brooks, Henry J Leese, Peter G Humpherson, Iain T Cameron, Tom P Fleming
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52791 (2012)
Previously, we have shown that a maternal low protein diet, fed exclusively during the preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the blastocyst stage a compensatory growth phenotype in late gestation and postna
Externí odkaz:
https://doaj.org/article/d5491b019d7a4ffbbff1308a03aa6fc6
Autor:
Natalia Igosheva, Andrey Y Abramov, Lucilla Poston, Judith J Eckert, Tom P Fleming, Michael R Duchen, Josie McConnell
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10074 (2010)
The negative impact of obesity on reproductive success is well documented but the stages at which development of the conceptus is compromised and the mechanisms responsible for the developmental failure still remain unclear. Recent findings suggest t
Externí odkaz:
https://doaj.org/article/ba34669e199a4ecda526410553580cff
Autor:
Judith Stephenson, Chittaranjan S. Yajnik, Adam J. Watkins, Richard Saffery, Judith J. Eckert, Mary Barker, Miguel A. Velazquez, Mark A. Hanson, Terrence Forrester, Andrew M. Prentice, Keith M. Godfrey, Tom P. Fleming, Peter D. Gluckman, John C. Mathers
Parental environmental factors, including diet, body composition, metabolism, and stress, affect the health and chronic disease risk of people throughout their lives, as captured in the Developmental Origins of Health and Disease concept. Research ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d2b54383b46dddabb70a6bffd6ccf
https://eprints.soton.ac.uk/417666/
https://eprints.soton.ac.uk/417666/
The preimplantation embryo undergoes morphogenesis to form a blastocyst largely independent of its external environment mediated through an intrinsic developmental program. However, the early embryo across species is sensitive to external cues such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de9f72fb4ad4c478cd74b305f8273a2
https://doi.org/10.1016/b978-0-12-801238-3.64515-4
https://doi.org/10.1016/b978-0-12-801238-3.64515-4
Publikováno v:
Journal of Developmental Origins of Health and Disease. 6:377-383
The early embryo and periconceptional period is a window during which environmental factors may cause permanent change in the pattern and characteristics of development leading to risk of adult onset disease. This has now been demonstrated across sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf72aa6135c82ad9d2dab5c0d1fd3ae
https://doi.org/10.1017/s2040174415001105
https://doi.org/10.1017/s2040174415001105
Publikováno v:
Advances in experimental medicine and biology. 1014
The early preimplantation embryo has been rigorously studied for decades to understand inherent reproductive and developmental mechanisms driving its morphogenesis from before fertilisation through to and beyond implantation. Recent research has demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddec300c1b280daf786e3b64858354e0
https://pubmed.ncbi.nlm.nih.gov/28864986
https://pubmed.ncbi.nlm.nih.gov/28864986