Calciphylaxis of the breast with associated diffuse dermal angiomatosis

Autor: Magdalene Hope Maung, Judith Hugh

Publikováno v: Human Pathology: Case Reports, Vol 9, Iss , Pp 5-9 (2017)

In 2013, approximately 660,000 Americans had end stage renal disease (ESRD), requiring either dialysis or transplantation. Up to 5% of dialysis dependent patients may develop calcific uremic arteriolopathy or calciphylaxis (CPX) with vascular medial

Externí odkaz: https://doaj.org/article/d2d11a0981aa4fb1a0fc61fbf9f573cd

Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections

Autor: Giuseppe Viale, Zuzana Kos, Allen M Gown, John M. S. Bartlett, Samuel C Y Leung, Andrew Dodson, Dongxia Gao, Frédérique Penault-Llorca, Jane Starczynski, Roberto Salgado, Mauro G. Mastropasqua, Sharon Nofech-Mozes, C. Kent Osborne, Signe Borgquist, Mitch Dowsett, Bert van der Vegt, Torsten O. Nielsen, Takuya Moriya, Takashi Sakatani, Tammy Piper, Carolina Gutierrez, Tomoharu Sugie, Anita Bane, Martin C. Chang, Susan Fineberg, Cornelia M Focke, Lila Zabaglo, Anna Ehinger, Lisa M. McShane, Sunil Badve, Daniel F. Hayes, Judith Hugh, Anne-Vibeke Lænkholm, Indu Arun

Publikováno v: Histopathology, 75(2), 225-235. Wiley
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A, Mastropasqua, M G, Moriya, T, Nofech-mozes, S, Osborne, C K, Penault-llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, Vegt, B, Viale, G, Hayes, D F, Mcshane, L M & Dowsett, M 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration ', Histopathology . https://doi.org/10.1111/his.13880
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A V, Mastropasqua, M G, Moriya, T, Nofech-Mozes, S, Osborne, C K, Penault-Llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, van der Vegt, B, Viale, G, Hayes, D F, McShane, L M, Dowsett, M & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections : an international multicentre collaboration ', Histopathology, vol. 75, no. 2, pp. 225-235 . https://doi.org/10.1111/his.13880

Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b17a84211148464ea55a0e4b7f71b32
https://research.rug.nl/en/publications/6062a661-6dbf-465f-a0f6-083331084619

Developing a clinical-pathologic model to predict genomic risk of recurrence in patients with hormone receptor positive, human epidermal growth factor receptor-2 negative, node negative breast cancer

Autor: Tasnima Abedin, Tanner Steed, Gilbert Bigras, Atul Batra, Judith Hugh, Karen King, Gloria Roldan-Urgoiti, NA Nixon, Sasha Lupichuk, Malek B. Hannouf

Publikováno v: Cancer Treatment and Research Communications, Vol 28, Iss, Pp 100401-(2021)

Introduction: Patients with hormone receptor (HR)-positive, human epidermal growth factor receptor-2 (HER2)-negative, node negative (NN) breast cancer may be offered a gene expression profiling (GEP) test to determine recurrence risk and benefit of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd7a68336bff806fee00cbf40e523e1
http://www.sciencedirect.com/science/article/pii/S246829422100099X

New Robust and Reproducible Stereological IHC Ki67 Breast Cancer Proliferative Assessment to Replace Traditional Biased Labeling Index

Autor: Judith Hugh, Hua Yang, Richard Berendt, Gilbert Bigras, George Wood, Wei-Feng Dong, Sarah Canil

Publikováno v: Applied Immunohistochemistry & Molecular Morphology

There is a pressing need for an objective decision tool to guide therapy for breast cancer patients that are estrogen receptor positive and HER2/neu negative. This subset of patients contains a mixture of luminal A and B tumors with good and bad outc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dd7540c64a8d4b4ea3842e4e4d3f1a
https://doi.org/10.1097/pai.0000000000000371

Single and Combinational siRNA Therapy of Cancer Cells: Probing Changes in Targeted and Nontargeted Mediators after siRNA Treatment

Autor: Parvin Mahdipoor, Hasan Uludağ, Judith Hugh, Hamidreza Montazeri Aliabadi, Marco Bisoffi

Publikováno v: Molecular Pharmaceutics. 13:4116-4128

Cancer cells are known to be heterogeneous and plastic, which imparts innate and acquired abilities to resist molecular targeting by short interfering RNA (siRNA). Not all cancer cells in a population would show a similar responsiveness to targeting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657a9bd6bf1866bdde0cf9f7daf3e8ee
https://doi.org/10.1021/acs.molpharmaceut.6b00711