Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Judith Hey"'
Autor:
Greisa Vila, Anton Luger, Aart Jan van der Lely, Sebastian J. C. M. M. Neggers, Susan M. Webb, Beverly M. K. Biller, Srinivas Valluri, Judith Hey-Hadavi
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
ContextHypertension is a major cardiovascular risk factor related to increased mortality in acromegaly. Surgical cure of acromegaly is associated with improvement in blood pressure levels, however little is known about the effect of pegvisomant (PEGV
Externí odkaz:
https://doaj.org/article/67bdf8f844374ea1a8b1de1c2ec9e0d9
Autor:
Steffen Müller, Xiati Guli, Judith Hey, Anne Einsle, Daniela Pfanz, Victor Sudmann, Timo Kirschstein, Rüdiger Köhling
Publikováno v:
Neurobiology of Disease, Vol 112, Iss , Pp 79-84 (2018)
Voltage-independent, Ca2+-activated K+ channels (KCa2.2, previously named SK2) are typically activated during a train of action potentials, and hence, are powerful regulators of cellular excitability by generating an afterhyperpolarizing potential (A
Externí odkaz:
https://doaj.org/article/9cedb749bb0f4e2da43307438e47c97c
Autor:
Frank Buttgereit, Dorothy McCabe, Eun Bong Lee, Vibeke Strand, Abraham Simon-Campos, Astrid Genet, Brinda Tammara, Ricardo Rojo, Judith Hey-Hadavi
Publikováno v:
RMD Open, Vol 5, Iss 1 (2019)
Objectives Glucocorticoids have anti-inflammatory, transrepression-mediated effects, although adverse events (AEs; transactivation-mediated effects) limit long-term use in patients with rheumatoid arthritis (RA). We evaluated the efficacy and safety
Externí odkaz:
https://doaj.org/article/27490c5cd49140ac8d65841e53348e83
Autor:
Camilo Jimenez, Greisa Vila, Anders F Mattsson, Judith Hey-Hadavi, Nicky Kelepouris, Anne Klibanski, Beverly M. K. Biller, Nicholas A. Tritos, Srinivas Rao Valluri
Publikováno v:
European Journal of Endocrinology. 182:285-292
Objective To examine all-cause mortality rates in patients with acromegaly on pegvisomant and identify pertinent risk factors, including insulin-like growth factor I (IGF-I). Design Retrospective cohort analysis of data from ACROSTUDY (global surveil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1745756bc79a4ae6ddf49f96a52fae1
https://doi.org/10.1530/eje-19-0794
https://doi.org/10.1530/eje-19-0794
Autor:
Roberto Salvatori, Maria Fleseriu, Aart Jan van der Lely, Thierry Brue, Michael Wajnrajch, Dagmar Führer-Sakel, Roy Gomez, Judith Hey-Hadavi, Andrew Palladino, Laura De Marinis, Srinivas Rao Valluri, Cecilia Camacho-Hübner, Joli van der Lans-Bussemaker
Publikováno v:
European Journal of Endocrinology
European Journal of Endocrinology, 2021, 185 (4), pp.525-538. ⟨10.1530/EJE-21-0239⟩
European Journal of Endocrinology, 2021, 185 (4), pp.525-538. ⟨10.1530/EJE-21-0239⟩
Objective To report the final long-term safety and efficacy analyses of patients with acromegaly treated with pegvisomant from the ACROSTUDY. Design Global (15 countries), multicentre, non-interventional study (2004–2017). Methods The complete ACRO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bd8c4bf1c0d81597f7c9ee3d9cb24a
https://hal-amu.archives-ouvertes.fr/hal-03586286
https://hal-amu.archives-ouvertes.fr/hal-03586286
Publikováno v:
Current Medical Research and Opinion. 35:963-973
Quality of life (QoL) and health economic data are becoming increasingly important factors in healthcare decision making. While there is a wealth of information establishing the benefit of growth hormone (GH) replacement therapy in adults with growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db188a42089e82565b13b10e835771f
https://doi.org/10.1080/03007995.2018.1546682
https://doi.org/10.1080/03007995.2018.1546682
Autor:
MC Peterson, Ricardo Rojo, Satoshi Shoji, Brinda Tammara, Daniela J. Conrado, A Suzuki, Judith Hey-Hadavi, Dorothy McCabe
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:439-448
Fosdagrocorat (PF-04171327), a dissociated agonist of the glucocorticoid receptor, has potent anti-inflammatory activity in patients with rheumatoid arthritis with reduced adverse effects on bone health. To identify fosdagrocorat doses with bone form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dd1818f4baea90740686eb0a41f4fb3
https://doi.org/10.1002/psp4.12201
https://doi.org/10.1002/psp4.12201
Autor:
Roy Gomez, Cecilia Camacho-Hubner, Jose Cara, Michael Wajnrajch, Andrew Palladino, der Lans Joli van, Jane Loftus, Roberto Salvatori, Nikoletta Kelepouris, Judith Hey-Hadavi, Maria Fleseriu
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5766413bb57a6516bfbaf3f652b66b75
https://doi.org/10.1530/endoabs.63.gp58
https://doi.org/10.1530/endoabs.63.gp58
Autor:
Dorothy McCabe, Vibeke Strand, Abraham Simon-Campos, Judith Hey-Hadavi, Brinda Tammara, Ricardo Rojo, Frank Buttgereit, Eun Bong Lee, Astrid Genet
Publikováno v:
RMD Open
ObjectivesGlucocorticoids have anti-inflammatory, transrepression-mediated effects, although adverse events (AEs; transactivation-mediated effects) limit long-term use in patients with rheumatoid arthritis (RA). We evaluated the efficacy and safety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a0c8adbd3b50f20135ea3e061baa8f
http://europepmc.org/articles/PMC6525626
http://europepmc.org/articles/PMC6525626
Autor:
Cecilia Camacho-Hübner, Susan M. Webb, Nicky Kelepouris, Michael Wajnrajch, Maria Fleseriu, Jane Loftus, Andrew Palladino, Thierry Brue, Roy Gomez, Judith Hey-Hadavi, Srinivas Rao Valluri, Roberto Salvatori, Jose Cara, Joli van der Lans
Publikováno v:
Journal of the Endocrine Society
Background: ACROSTUDY is an open-label, non-interventional post-authorization safety study that began in 2004 to evaluate safety in at least 1000 acromegaly patients treated with the GH receptor antagonist pegvisomant (PEGV). This commitment was fulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4948d1846b0d09a412834f699cc42b19
http://europepmc.org/articles/PMC6553204
http://europepmc.org/articles/PMC6553204