Výsledky vyhledávání - "Judith Graff"

Mutations within Potential Glycosylation Sites in the Capsid Protein of Hepatitis E Virus Prevent the Formation of Infectious Virus Particles

Autor: Suzanne U. Emerson, Robert H. Purcell, Yi-Hua Zhou, Hanh T. Nguyen, Marisa St. Claire, Claro Yu, Udana Torian, Judith Graff

Publikováno v: Journal of Virology. 82:1185-1194

Hepatitis E virus is a nonenveloped RNA virus. However, the single capsid protein resembles a typical glycoprotein in that it contains a signal sequence and potential glycosylation sites that are utilized when recombinant capsid protein is overexpres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ddae6d70f26735efca12c242efa014
https://doi.org/10.1128/jvi.01219-07

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A Bicistronic Subgenomic mRNA Encodes both the ORF2 and ORF3 Proteins of Hepatitis E Virus

Autor: Udana Torian, Hanh Nguyen, Suzanne U. Emerson, Judith Graff

Publikováno v: Journal of Virology. 80:5919-5926

Hepatitis E virus replicons containing the neomycin resistance gene expressed from open reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines containing functional replicons were selected by constant exposure to G418

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239a29f47b1ba870edf4236376712fe7
https://doi.org/10.1128/jvi.00046-06

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In Vitro Replication of Hepatitis E Virus (HEV) Genomes and of an HEV Replicon Expressing Green Fluorescent Protein

Autor: Hanh T. Nguyen, Suzanne U. Emerson, Alicia Brockington, David A. Stephany, Robert H. Purcell, Judith Graff

Publikováno v: Journal of Virology. 78:4838-4846

Hepatitis E virus (HEV) RNA replication occurred in seven of nine primate cell cultures transfected with in vitro transcripts of an infectious cDNA clone. Cell-to-cell spread did not occur in cell cultures, but rhesus monkeys inoculated with lysates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b04b58ac452bdd84386a9b5680844d7
https://doi.org/10.1128/jvi.78.9.4838-4846.2004

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Hepatitis A Virus Capsid Protein VP1 Has a Heterogeneous C Terminus

Autor: Shirley A. Harmon, Kristine M. Swiderek, Michael T. Davis, Xi-Yu Jia, Judith Graff, Oliver C. Richards, Ellie Ehrenfeld, Donald F. Summers, Felicia Rusnak

Publikováno v: Journal of Virology. 73:6015-6023

Hepatitis A virus (HAV) encodes a single polyprotein which is posttranslationally processed into the functional structural and nonstructural proteins. Only one protease, viral protease 3C, has been implicated in the nine protein scissions. Processing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440b77dc6f9d44edab1bf70e116601a9
https://doi.org/10.1128/jvi.73.7.6015-6023.1999

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Interaction of Poly(rC) Binding Protein 2 with the 5′ Noncoding Region of Hepatitis A Virus RNA and Its Effects on Translation

Autor: John Cha, Lawrence B. Blyn, Ellie Ehrenfeld, Judith Graff

Publikováno v: Journal of Virology. 72:9668-9675

Utilization of internal ribosome entry segment (IRES) structures in the 5′ noncoding region (5′NCR) of picornavirus RNAs for initiation of translation requires a number of host cell factors whose distribution may vary in different cells and whose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c451dbff1ce747718436ff67bfa0b96
https://doi.org/10.1128/jvi.72.12.9668-9675.1998

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Influence of the 5' noncoding region of hepatitis A virus strain GBM on its growth in different cell lines

Autor: Andrea Normann, Bertram Flehmig, Judith Graff

Publikováno v: Journal of General Virology. 78:1841-1849

Previous sequence analysis of consecutive passages of the hepatitis A virus (HAV) strain GBM/WT in human embryonic kidney cells (HEK cells), human embryonic lung fibroblasts (HFS cells) and in FRhK-4 cells (foetal rhesus monkey kidney cells) pointed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c02978ebe2c2fdfb4ce913406181e0d
https://doi.org/10.1099/0022-1317-78-8-1841

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Nucleotide sequence of wild-type hepatitis A virus GBM in comparison with two cell culture-adapted variants

Autor: Judith Graff, Bertram Flehmig, Andrea Normann, S M Feinstone

Publikováno v: Journal of Virology. 68:548-554

In order to study cell tropism and attenuation of hepatitis A virus (HAV), the genome of HAV wild-type GBM and two cell culture-adapted variants, GBM/FRhK and GBM/HFS, were cloned and sequenced after amplification by reverse transcriptase-PCR. During

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92c04d1dda1f6291e0a8cbd11d56d0b
https://doi.org/10.1128/jvi.68.1.548-554.1994

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The Open Reading Frame 3 Gene of Hepatitis E Virus Contains a cis-Reactive Element and Encodes a Protein Required for Infection of Macaques

Autor: Suzanne U. Emerson, William R. Elkins, Marisa St. Claire, Claro Yu, Judith Graff, Robert H. Purcell, Hanh T. Nguyen

An infectious cDNA clone of hepatitis E virus was mutated in order to prevent synthesis of either open reading frame 2 (ORF2) protein or ORF3 protein. HuH-7 cells transfected with an ORF2-null mutant produced ORF3, and those transfected with an ORF3-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b0f52572183f2ecb0db03136d33e48
https://europepmc.org/articles/PMC1112134/

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