Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Judith Fischer‐Sternjak"'
Autor:
Christina Koupourtidou, Veronika Schwarz, Hananeh Aliee, Simon Frerich, Judith Fischer-Sternjak, Riccardo Bocchi, Tatiana Simon-Ebert, Xianshu Bai, Swetlana Sirko, Frank Kirchhoff, Martin Dichgans, Magdalena Götz, Fabian J. Theis, Jovica Ninkovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Traumatic brain injury leads to a highly orchestrated immune- and glial cell response partially responsible for long-lasting disability and the development of secondary neurodegenerative diseases. A holistic understanding of the mechanisms c
Externí odkaz:
https://doaj.org/article/48c6ec864964436f8a281ba154e18ca0
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons
Autor:
Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-20 (2022)
Abstract Direct reprogramming based on genetic factors resembles a promising strategy to replace lost cells in degenerative diseases such as Parkinson's disease. For this, we developed a knock‐in mouse line carrying a dual dCas9 transactivator syst
Externí odkaz:
https://doaj.org/article/d6d64f7bdd884a3b9299b97fa956cf9b
Autor:
Christina Koupourtidou, Veronika Schwarz, Hananeh Aliee, Simon Frerich, Judith Fischer-Sternjak, Riccardo Bocchi, Tatiana Simon-Ebert, Martin Dichgans, Magdalena Götz, Fabian Theis, Jovica Ninkovic
Traumatic brain injury leads to a highly orchestrated immune- and glial cell response partially responsible for long-lasting disability and the development of secondary neurodegenerative diseases. A holistic understanding of the mechanisms controllin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc6bd597b081c3e1ffea40c6ff68fba
https://doi.org/10.1101/2023.02.24.529840
https://doi.org/10.1101/2023.02.24.529840
Autor:
Majid Ghareghani, Judith Fischer-Sternjak, Alina Marymonchyk, Marina Snapyan, Archana Gengatharan, Jovica Ninkovic, Sarah Malvaut, Armen Saghatelyan, Magdalena Götz
Publikováno v:
Cell 184, 709-722.e13 (2021)
Neural stem cells (NSCs) in the adult brain transit from the quiescent state to proliferation to produce new neurons. The mechanisms regulating this transition in freely behaving animals are, however, poorly understood. We customized invivo imaging p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d5d764410d6c6adb1c89a0074a907b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61064
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61064
Autor:
Moritz J. Rossner, Swetlana Sirko, Solène Clavreul, Tatiana Simon-Ebert, Manja Thorwirth, Nirmal Kannayian, Pawel Smialowski, Judith Fischer-Sternjak, Magdalena Götz, Riccardo Bocchi, Sabine Ulbricht, Stefanie Ohlig
Publikováno v:
EMBO J.:e107532 (2021)
The EMBO Journal
The EMBO Journal
Astrocytes regulate brain‐wide functions and also show region‐specific differences, but little is known about how general and region‐specific functions are aligned at the single‐cell level. To explore this, we isolated adult mouse diencephali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a13462280d112cd040716a7ed4a80a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63088
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63088
Autor:
David C. Martinelli, Favio Salinas, Christian Friess, Magdalena Götz, Jovica Ninkovic, Herbert B. Schiller, Jürgen Cox, Amelia J Thompson, Matthew J. Sticco, Kristian Franze, Judith Fischer-Sternjak, Jacob Kjell
Publikováno v:
Cell Stem Cell 26, 277-293.e8 (2020)
Cell Stem Cell
CELL STEM CELL
Cell Stem Cell
CELL STEM CELL
Summary The mammalian brain contains few niches for neural stem cells (NSCs) capable of generating new neurons, whereas other regions are primarily gliogenic. Here we leverage the spatial separation of the sub-ependymal zone NSC niche and the olfacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5abeb3f43440fb5457f9c0898161c26
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58097
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58097