Výsledky vyhledávání - "Judith Field"

Akademický článek

A dataset examining technical factors on fixed white blood cell single-cell RNA-seqGene expression Omnibus

Autor: Daniel V Brown, Agnieszka Swierczak, Yue You, Yupei You, Daniela Amann-Zalcenstein, Peter Hickey, Arthur Hsu, Matthew E. Ritchie, Monther Alhamdoosh, Judith Field, Rory Bowden

Publikováno v: Data in Brief, Vol 57, Iss , Pp 111096- (2024)

Single-cell RNA sequencing (scRNA-seq) is a powerful technology that enables the measurement of gene expression in individual cells. Such precision provides insights into cellular heterogeneity that bulk methods might overlook. Fragile cells, in part

Externí odkaz: https://doaj.org/article/f5257f530f9f48c0ae156d3e0fe3d9b5

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Akademický článek

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status.

Publikováno v: PLoS Genetics, Vol 12, Iss 3, p e1005853 (2016)

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The risk of developing MS is strongly influenced by genetic predisposition, and over 100 loci have been established as associated with susceptibili

Externí odkaz: https://doaj.org/article/0cd521e396da40b7bb93def308a10e36

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Akademický článek

The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.

Autor: Judith Field, Fernando Shahijanian, Stephen Schibeci, Australia and New Zealand MS Genetics Consortium (ANZgene), Laura Johnson, Melissa Gresle, Louise Laverick, Grant Parnell, Graeme Stewart, Fiona McKay, Trevor Kilpatrick, Helmut Butzkueven, David Booth

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0127080 (2015)

Human genetic and animal studies have implicated the costimulatory molecule CD40 in the development of multiple sclerosis (MS). We investigated the cell specific gene and protein expression variation controlled by the CD40 genetic variant(s) associat

Externí odkaz: https://doaj.org/article/167c9d164d5148e8bf2b8d3c545710f1

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Akademický článek

Earliest Pottery on New Guinea Mainland Reveals Austronesian Influences in Highland Environments 3000 Years Ago.

Autor: Dylan Gaffney, Glenn R Summerhayes, Anne Ford, James M Scott, Tim Denham, Judith Field, William R Dickinson

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0134497 (2015)

Austronesian speaking peoples left Southeast Asia and entered the Western Pacific c.4000-3000 years ago, continuing on to colonise Remote Oceania for the first time, where they became the ancestral populations of Polynesians. Understanding the impact

Externí odkaz: https://doaj.org/article/65d872ac66ed4d9b92a723bd0871c520

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Akademický článek

Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility.

Autor: Gerry Z M Ma, Jim Stankovich, Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Trevor J Kilpatrick, Michele D Binder, Judith Field

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e16964 (2011)

Multiple sclerosis (MS) is a debilitating, chronic demyelinating disease of the central nervous system affecting over 2 million people worldwide. The TAM family of receptor tyrosine kinases (TYRO3, AXL and MERTK) have been implicated as important pla

Externí odkaz: https://doaj.org/article/4fc7f388196f48d39cbfd9d636a89161

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Akademický článek

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e13454 (2010)

We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we identified seven SNPs that we

Externí odkaz: https://doaj.org/article/666c12ee17314e0d830ff51e46de6064

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Akademický článek

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients.

Autor: Cathy J Jensen, Jim Stankovich, Anneke Van der Walt, Melanie Bahlo, Bruce V Taylor, Ingrid A F van der Mei, Simon J Foote, Trevor J Kilpatrick, Laura J Johnson, Ella Wilkins, Judith Field, Patrick Danoy, Matthew A Brown, Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Justin P Rubio, Helmut Butzkueven

Publikováno v: PLoS ONE, Vol 5, Iss 4, p e10003 (2010)

Recent association studies in multiple sclerosis (MS) have identified and replicated several single nucleotide polymorphism (SNP) susceptibility loci including CLEC16A, IL2RA, IL7R, RPL5, CD58, CD40 and chromosome 12q13-14 in addition to the well est

Externí odkaz: https://doaj.org/article/13cb2becb1be45648188bdae2e91bbeb

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Akademický článek

Variants of ST8SIA1 are associated with risk of developing multiple sclerosis.

Autor: Seema Husain, Cagri Yildirim-Toruner, Justin P Rubio, Judith Field, Southern MS Genetics Consortium, Marvin Schwalb, Stuart Cook, Marcella Devoto, Emilia Vitale

Publikováno v: PLoS ONE, Vol 3, Iss 7, p e2653 (2008)

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both genetic and environmental factors playing a role in susceptibility. To date, the HLA DR15/DQ6 haplotype within the major hist

Externí odkaz: https://doaj.org/article/29284e3ed38c4bfcacc9da58ad36dced

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