Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Judith E. Epstein"'
Autor:
Thomas L. Richie, L.W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei-Chun Chen, Yonas Abebe, Natasha KC, Sumana Chakravarty, David Dolberg, Sara A. Healy, Halimatou Diawara, Mahamadou S. Sissoko, Issaka Sagara, David M. Cook, Judith E. Epstein, Benjamin Mordmüller, Melissa Kapulu, Andrea Kreidenweiss, Blandine Franke-Fayard, Selidji T. Agnandji, María-Silvia A. López Mikue, Matthew B.B. McCall, Laura Steinhardt, Martina Oneko, Ally Olotu, Ashley M. Vaughan, James G. Kublin, Sean C. Murphy, Said Jongo, Marcel Tanner, Sodiomon B. Sirima, Matthew B. Laurens, Claudia Daubenberger, Joana C. Silva, Kirsten E. Lyke, Chris J. Janse, Meta Roestenberg, Robert W. Sauerwein, Salim Abdulla, Alassane Dicko, Stefan H. I. Kappe, B. Kim Lee Sim, Patrick E. Duffy, Peter G. Kremsner, Stephen L. Hoffman
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especi
Externí odkaz:
https://doaj.org/article/64ccc130995e4fbda0570808ef7ca47d
Autor:
Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vacc
Externí odkaz:
https://doaj.org/article/8adef3faef374367ad0d7275f5f65245
Autor:
Natasha KC, L. W. Preston Church, Pouria Riyahi, Sumana Chakravarty, Robert A. Seder, Judith E. Epstein, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Mahamadou S. Sissoko, Sara Healy, Patrick E. Duffy, Said A. Jongo, Vicente Urbano Nsue Ndong Nchama, Salim Abdulla, Maxmillian Mpina, Sodiomon B. Sirima, Matthew B. Laurens, Laura C. Steinhardt, Martina Oneko, MingLin Li, Tooba Murshedkar, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundWhile prior research has shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could elucidate i
Externí odkaz:
https://doaj.org/article/d6334f1741f1482b91e5bb9239e66e76
Autor:
Fergal J. Duffy, Ying Du, Jason Carnes, Judith E. Epstein, Stephen L. Hoffman, Salim Abdulla, Said Jongo, Maxmillian Mpina, Claudia Daubenberger, John D. Aitchison, Ken Stuart
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Vaccination with radiation-attenuated Plasmodium falciparum sporozoites is known to induce protective immunity. However, the mechanisms underlying this protection remain unclear. In this work, two recent radiation-attenuated sporo
Externí odkaz:
https://doaj.org/article/cb869f93c4374310b33c25bf3aa76c3e
Autor:
Tanmaya Atre, Tanisha M. Robinson, Tatyana Savransky, Sheetij Dutta, Judith E. Epstein, Elke S. Bergmann-Leitner
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-8 (2019)
Abstract Background Whole parasite vaccination is an efficacious strategy to induce sterile immunity and to prevent malaria transmission. Understanding the mechanism and response of immune cells to vaccines plays a critical role in deciphering correl
Externí odkaz:
https://doaj.org/article/995d8aaebc824385819d078dafbfd4ca
Autor:
Sidhartha Chaudhury, Chenggang Yu, Ruifeng Liu, Kamal Kumar, Samantha Hornby, Christopher Duplessis, Joel M. Sklar, Judith E. Epstein, Jaques Reifman
Publikováno v:
IEEE Transactions on Biomedical Engineering. 69:2119-2129
Observational studies on the use of commercially available wearable devices for infection detection lack the rigor of controlled clinical studies, where time of exposure and onset of infection are exactly known. Towards that end, we carried out a fea
Autor:
Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Controlled human malaria infection (CHMI) has supported Plasmodium falciparum (Pf) malaria vaccine development by providing preliminary estimates of vaccine efficacy (VE). Because CHMIs generally use Pf strains similar to vaccine strains, VE against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61eb7a584b451fef55118be0cd72830d
https://doi.org/10.1101/2021.12.09.21266528
https://doi.org/10.1101/2021.12.09.21266528
Autor:
Sharina Reyes, Anatalio Reyes, Judith E. Epstein, Michael R. Hollingdale, Bradley Hickey, Sandra Inoue, Eileen Villasante, Nimfa Teneza-Mora, Jun Huang, Harini Ganeshan, Jo Glenna Banania, Arnel Belmonte, Ivelese Guzman, Maria Belmonte, Rachel Velasco, Thomas L. Richie, Martha Sedegah, Joanne M. Lumsden
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256396 (2021)
PLoS ONE, Vol 16, Iss 8, p e0256396 (2021)
Background Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that
Autor:
Arnel Belmonte, Ivelese Guzman, D Bellamy, Cindy Tamminga, Michael R. Hollingdale, Eleanor Berrie, Jo Glenna Banania, Elke S. Bergmann-Leitner, Martha Sedegah, Judith E. Epstein, Maria Belmonte, Sharina Reyes, Eileen Villasante, Anatalio Reyes, Yolanda Alcorta, Tida Lee, Rachel Velasco, Devin Hunt, Katie J. Ewer, Thomas L. Richie, Keith Limbach, Kalpana Gowda, Alison M. Lawrie, Jack Hutter, Marvin J Sklar, Nehkonti Adams, Noelle B. Patterson, Lindsey S. Garver, Ashley Lindstrom, Nimfa Teneza-Mora, M Bittaye, Lorraine Soisson, Carter L. Diggs, Mimi Wong, Harini Ganeshan, Ilin Chuang, Sandra Inoue, Adrian V. S. Hill, Christopher A. Duplessis, Jun Huang, K. Monique Hollis-Perry, Santina Maiolatesi, Kelli Bankard, Sidhartha Chaudhury
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256980 (2021)
PLoS ONE
PLoS ONE
BackgroundA DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encodingPlasmodium falciparum(Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against controlled hum
Autor:
Jun Huang, Anita Manoj, Matthew B. Laurens, Peter F. Billingsley, Arnel Belmonte, Mimi Wong, Ivelese Guzman, Martha Sedegah, Warfighter Ii Study Team, B. Kim Lee Sim, Thomas L. Richie, Judith E. Epstein, Tooba Murshedkar, Sharina Reyes, Harini Ganeshan, Stephen L. Hoffman, Lindsey S Garver Baldwin, Anusha Gunasekera, Kirsten E. Lyke, Sumana Chakravarty, Eric R. James, W Preston Church, Alexandra Singer, Eileen Villasante, Amelia Ozemoya, Glenna Banania, Maria Belmonte, Anatalio Reyes, Andrea A. Berry
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 73(7)
Background A live-attenuated Plasmodium falciparum sporozoite (SPZ) vaccine (PfSPZ Vaccine) has shown up to 100% protection against controlled human malaria infection (CHMI) using homologous parasites (same P. falciparum strain as in the vaccine). Us