Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Judith Derdelinckx"'
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Nowadays, it has become clear that extracellular vesicles (EVs) are not a cellular waste disposal vesicle but are an essential part of an intercellular communication system. Besides the use of EVs in biomarker studies and diagnostics, the po
Externí odkaz:
https://doaj.org/article/bbccc78f589b45f198e26f2643b9ec9e
Autor:
Anna-Victoria De Keersmaecker, Eline Van Doninck, Veronica Popescu, Lander Willem, Melissa Cambron, Guy Laureys, Miguel D’ Haeseleer, Maria Bjerke, Ella Roelant, Marc Lemmerling, Marie Beatrice D’hooghe, Judith Derdelinckx, Tatjana Reynders, Barbara Willekens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite advances in immunomodulatory treatments of multiple sclerosis (MS), patients with non-active progressive multiple sclerosis (PMS) continue to face a significant unmet need. Demyelination, smoldering inflammation and neurodegenerat
Externí odkaz:
https://doaj.org/article/a9cabf3e9b4e4e489a1794669330c6d9
Autor:
Mats Van Delen, Ibo Janssens, Amber Dams, Laurence Roosens, Benson Ogunjimi, Zwi N. Berneman, Judith Derdelinckx, Nathalie Cools
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15201 (2022)
Although the global pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still ongoing, there are currently no specific and highly efficient drugs for COVID-19 available, particularly in severe cases. Recent fi
Externí odkaz:
https://doaj.org/article/772dc7eef0a646a099aed2843a3843cd
Autor:
Judith Derdelinckx, María José Mansilla, Maxime De Laere, Wai-Ping Lee, Juan Navarro-Barriuso, Inez Wens, Irene Nkansah, Jasmijn Daans, Hans De Reu, Aneta Jolanta Keliris, Johan Van Audekerke, Verdi Vanreusel, Zoë Pieters, Annemie Van der Linden, Marleen Verhoye, Geert Molenberghs, Niel Hens, Herman Goossens, Barbara Willekens, Patrick Cras, Peter Ponsaerts, Zwi N. Berneman, Eva María Martínez-Cáceres, Nathalie Cools
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-20 (2019)
Abstract Background Although effective in reducing relapse rate and delaying progression, current therapies for multiple sclerosis (MS) do not completely halt disease progression. T cell autoimmunity to myelin antigens is considered one of the main m
Externí odkaz:
https://doaj.org/article/2366a29bc50643d4a9477ae81546bc64
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antigen-specific therapy for multiple sclerosis may lead to a more effective therapy by induction of tolerance to a wide range of myelin-derived antigens without hampering the normal surveillance and effector function of the immune system. Numerous a
Externí odkaz:
https://doaj.org/article/802075c01ae84ab495874bf2c3612acc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7536 (2021)
Currently, there is still no cure for multiple sclerosis (MS), which is an autoimmune and neurodegenerative disease of the central nervous system. Treatment options predominantly consist of drugs that affect adaptive immunity and lead to a reduction
Externí odkaz:
https://doaj.org/article/4ef914351b484fe98b230c364cb2c003
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7925 (2021)
Cell-based therapies are gaining momentum as promising treatments for rare neurological autoimmune diseases, including neuromyelitis optica spectrum disorders and myelin oligodendrocyte glycoprotein antibody-associated disease. The development of tar
Externí odkaz:
https://doaj.org/article/97f12bb6be3548d2b5031c2c39555bb6
Autor:
Judith Derdelinckx, Irene Nkansah, Naomi Ooms, Laura Van Bruggen, Marie-Paule Emonds, Liesbeth Daniëls, Tatjana Reynders, Barbara Willekens, Patrick Cras, Zwi N. Berneman, Nathalie Cools
Publikováno v:
Cells, Vol 9, Iss 12, p 2703 (2020)
Background: When aiming to restore myelin tolerance using antigen-specific treatment approaches in MS, the wide variety of myelin-derived antigens towards which immune responses are targeted in multiple sclerosis (MS) patients needs to be taken into
Externí odkaz:
https://doaj.org/article/df725cb8ea9d4360bbda100bfeb77d97
Autor:
Maxime De Laere, Judith Derdelinckx, Mari Hassi, Mari Kerosalo, Heidi Oravamäki, Johan Van den Bergh, Zwi Berneman, Nathalie Cools
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
The use of tolerance-inducing dendritic cells (tolDCs) has been proven to be safe and well tolerated in the treatment of autoimmune diseases. Nevertheless, several challenges remain, including finding ways to facilitate the migration of cell therapeu
Externí odkaz:
https://doaj.org/article/43fa7266121c4b16a13019c9b51debbe
Autor:
Abdu Kisekka, Musubire, Judith, Derdelinckx, Tatjana, Reynders, David B, Meya, Paul R, Bohjanen, Patrick, Cras, Barbara, Willekens
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 8(6)
Neuromyelitis optica (NMO) is a CNS inflammatory disease that predominantly affects the optic nerves and the spinal cord. It is more frequent in Asian and African populations than in European ones. Data on epidemiology, clinical presentation, additio