Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Judith A. West-Mays"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11988 (2021)
Fibrotic cataracts have been attributed to transforming growth factor-beta (TGF-β)-induced epithelial-to-mesenchymal transition (EMT). Using mouse knockout (KO) models, our laboratory has identified MMP9 as a crucial protein in the TGF-β-induced EM
Externí odkaz:
https://doaj.org/article/280609783340456ba2978db6d68b59bb
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8730 (2021)
The cornea is an anterior eye structure specialized for vision. The corneal endothelium and stroma are derived from the periocular mesenchyme (POM), which originates from neural crest cells (NCCs), while the stratified corneal epithelium develops fro
Externí odkaz:
https://doaj.org/article/ecbfe8ecd2a147e6b68a1b0f233c9712
Autor:
Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 8, Pp 849-861 (2016)
Anterior segment dysgenesis (ASD) encompasses a group of developmental disorders in which a closed angle phenotype in the anterior chamber of the eye can occur and 50% of patients develop glaucoma. Many ASDs are thought to involve an inappropriate pa
Externí odkaz:
https://doaj.org/article/4cdfc075073c4fa58b4f0cbdb6e77bdf
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2078 (2019)
Cataracts are the leading cause of blindness worldwide. Although surgery is a successful method to restore vision loss due to cataracts, post-surgical complications can occur, such as secondary cataracts, also known as posterior capsular opacificatio
Externí odkaz:
https://doaj.org/article/0c03b0e33c664deeb1c4677b8ef23d1d
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11988, p 11988 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11988, p 11988 (2021)
Fibrotic cataracts have been attributed to transforming growth factor-beta (TGF-β)-induced epithelial-to-mesenchymal transition (EMT). Using mouse knockout (KO) models, our laboratory has identified MMP9 as a crucial protein in the TGF-β-induced EM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cea81d55b2ea12db6a5ede0599306d1
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8730, p 8730 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8730, p 8730 (2021)
The cornea is an anterior eye structure specialized for vision. The corneal endothelium and stroma are derived from the periocular mesenchyme (POM), which originates from neural crest cells (NCCs), while the stratified corneal epithelium develops fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87524c6a761c850fb23dd92db270b2a
Autor:
Anthony Saraco, Trevor Williams, Aftab Taiyab, Alexander K. Ball, Paula Deschamps, Monica Akula, Judith A. West-Mays
Publikováno v:
Curr Eye Res
PURPOSE: Our lab has shown that conditionally disrupting the transcription factor activating protein 2β (Tfap2b) gene, responsible for the activating protein-2β (AP-2β) transcription factor, exclusively in cranial neural crest cells (AP-2β NCC KO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7aface918af82037902d70cfc6465e
https://pubmed.ncbi.nlm.nih.gov/33689532
https://pubmed.ncbi.nlm.nih.gov/33689532
Autor:
Monica Akula, Judith A. West-Mays, Paula Deschamps, Shannin Yee, Aftab Taiyab, Alexander K. Ball, Trevor Williams
Publikováno v:
Exp Eye Res
Previously, we have shown that Tfap2b, the gene encoding transcription factor AP-2β, is needed for normal mouse eye development. Specifically, targeted loss of Tfap2b in neural crest cells (NCCs)(1) and their derivatives, particularly the periocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bae4305c9b65e6ed016a5643fd5f8f0
https://pubmed.ncbi.nlm.nih.gov/32353428
https://pubmed.ncbi.nlm.nih.gov/32353428
Publikováno v:
Journal of Neuroscience Research. 97:7-15
Development of the eye is closely associated with neural crest cell migration and specification. Eye development is extremely complex, as it requires the working of a combination of local factors, receptors, inductors, and signaling interactions betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5595bdf1ae71ecbdabd2cba06e73307
https://doi.org/10.1002/jnr.24245
https://doi.org/10.1002/jnr.24245
Autor:
Trevor Williams, Michael D. Noseworthy, Judith A. West-Mays, Emily Anne Hicks, Mizna Zaveri, Paula Deschamps, Alexander K. Ball
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The combined action of the activating protein-2 (AP-2) transcription factors, AP-2α and AP-2β, is important in early retinal development, specifically in the formation of horizontal cells. However, in previous studies, it was not possible t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510c41c1e3cb0ddf445d7dda77ab9b3c
http://europepmc.org/articles/PMC5931233
http://europepmc.org/articles/PMC5931233