Activity and expression of Xenopus laevis matrix metalloproteinases: Identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammalsJae‐Chang Jung and Judith A. West‐Mays contributed equally to the study.

Autor: Jae‐Chang Jung¹, Judith A. West‐Mays¹, Brian M. Stramer¹, Michael H. Byrne², Sumi Scott¹, Mehernosh K. Mody¹, Peter M. Sadow¹, Stephen M. Krane², M. Elizabeth Fini¹

Publikováno v: Journal of Cellular Physiology. Oct2004, Vol. 201 Issue 1, p155-164. 10p.

Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification

Autor: Haydn Walker, Aftab Taiyab, Paula Deschamps, Trevor Williams, Judith A. West-Mays

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 16, p 8730 (2021)

The cornea is an anterior eye structure specialized for vision. The corneal endothelium and stroma are derived from the periocular mesenchyme (POM), which originates from neural crest cells (NCCs), while the stratified corneal epithelium develops fro

Externí odkaz: https://doaj.org/article/ecbfe8ecd2a147e6b68a1b0f233c9712

Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma

Autor: Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays

Publikováno v: Disease Models & Mechanisms, Vol 9, Iss 8, Pp 849-861 (2016)

Anterior segment dysgenesis (ASD) encompasses a group of developmental disorders in which a closed angle phenotype in the anterior chamber of the eye can occur and 50% of patients develop glaucoma. Many ASDs are thought to involve an inappropriate pa

Externí odkaz: https://doaj.org/article/4cdfc075073c4fa58b4f0cbdb6e77bdf

MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens

Autor: Aftab Taiyab, Judith A. West-Mays, Zi Zhen Ginny Liu

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11988, p 11988 (2021)

Fibrotic cataracts have been attributed to transforming growth factor-beta (TGF-β)-induced epithelial-to-mesenchymal transition (EMT). Using mouse knockout (KO) models, our laboratory has identified MMP9 as a crucial protein in the TGF-β-induced EM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cea81d55b2ea12db6a5ede0599306d1

Progressive Loss of Retinal Ganglion Cells in Activating Protein-2β Neural Crest Cell Knockout Mice

Autor: Anthony Saraco, Trevor Williams, Aftab Taiyab, Alexander K. Ball, Paula Deschamps, Monica Akula, Judith A. West-Mays

Publikováno v: Curr Eye Res

PURPOSE: Our lab has shown that conditionally disrupting the transcription factor activating protein 2β (Tfap2b) gene, responsible for the activating protein-2β (AP-2β) transcription factor, exclusively in cranial neural crest cells (AP-2β NCC KO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7aface918af82037902d70cfc6465e
https://pubmed.ncbi.nlm.nih.gov/33689532