Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Judith A. Strauss"'
Publikováno v:
Sarcoma, Vol 2011 (2011)
Radiotherapy used in the treatment of pediatric musculoskeletal sarcomas may result in crippling defects of skeletal growth. Several radioprotective strategies have shown potential for preserving function of the irradiated epiphysis but have not been
Externí odkaz:
https://doaj.org/article/43d48c7c2af44744bf907d19ef0da4fd
Autor:
Chad E. Hartley, Shengle Zhang, John P. Fischer, Sejal Shah, Judith A. Strauss, Richard Riccardi, Madhu Varma, Zhong Jin Yang
Publikováno v:
Journal of Neurosurgery. 109:708-714
Object Head trauma is a dynamic process characterized by a cascade of metabolic and molecular events. Erythropoietin (EPO) has been shown to have neuroprotective effects in animal models of traumatic brain injury (TBI). Acute in vivo mechanisms and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::225611c1510e7468d2820e0d095e11de
https://doi.org/10.3171/jns/2008/109/10/0708
https://doi.org/10.3171/jns/2008/109/10/0708
Autor:
Cornelia E. Farnum, Timothy A. Damron, Joseph A. Spadaro, Jason A. Horton, Jason T. Bariteau, Judith A. Strauss, Bryan S. Margulies
Publikováno v:
Journal of Orthopaedic Research. 24:1945-1956
Radiation therapy encompassing an active epiphysis can negatively impact the potential for bone growth by disrupting cell-cycle progression and accelerating apoptosis and terminal differentiation in physeal chondrocytes. Despite functional derangemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8022cbc867e52128d045822905d2e030
https://doi.org/10.1002/jor.20251
https://doi.org/10.1002/jor.20251
Autor:
Jay Luther, Bryan S. Margulies, Judith A. Strauss, Cornelia E. Farnum, Joseph A. Spadaro, Jason A. Horton, Timothy A. Damron
Publikováno v:
International Journal of Radiation Biology. 81:759-765
The aim of this study was to determine if fractionation and individual or combinations of radioprotectants could minimize damage to physeal longitudinal growth in an animal model to any greater extent than fractionation alone.Sixty-three weanling mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a1aa71e013502da94325abcbeae445
https://doi.org/10.1080/09553000500495710
https://doi.org/10.1080/09553000500495710
Autor:
Timothy A. Damron, Cornelia E. Farnum, Bryan S. Margulies, Judith A. Strauss, Jason A. Horton, Joseph A. Spadaro
Publikováno v:
Clinical Orthopaedics and Related Research. 426:110-116
Radiotherapy used in the treatment of bone and soft tissue sarcomas in pediatric patients often results in undesirable growth plate damage. Radioprotectants may hold promise in the selective protection of growth plate tissue in this setting. In an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8548725431b0ad5d190ffb1dc525f50a
https://doi.org/10.1097/01.blo.0000131247.18112.0f
https://doi.org/10.1097/01.blo.0000131247.18112.0f
Autor:
Asghar Naqvi, Cornelia E. Farnum, William D. Grant, Joseph A. Spadaro, Judith A. Strauss, Timothy A. Damron, Jason A. Horton, Bryan S. Margulies
Publikováno v:
Clinical Orthopaedics and Related Research. 422:233-242
The effects of irradiation on growth plate chondrocytes and mediators of chondrocytic differentiation are poorly understood. In earlier work on rat growth plate changes 1/2 to 4 weeks after irradiation, a nadir was identified at 1 week in proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f331cdffb71b048e42884c09e4cd60
https://doi.org/10.1097/01.blo.0000129344.28160.9d
https://doi.org/10.1097/01.blo.0000129344.28160.9d
Autor:
Cornelia E. Farnum, Jason A. Horton, Joseph A. Spadaro, B. S. Margulies, Judith A. Strauss, Timothy A. Damron
Publikováno v:
International Journal of Radiation Biology. 80:217-228
To determine if pentoxifylline, interleukin 1alpha, selenium and misoprostol can minimize damage to physeal longitudinal growth during single radiation dose exposure in an animal model.Eighty-seven weanling Sprague-Dawley rats were randomized into 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002289c0d25a78821fd62cdd2f92a60c
https://doi.org/10.1080/09553000410001669524
https://doi.org/10.1080/09553000410001669524
Autor:
Jason A. Horton, Bryan S. Margulies, Judith A. Strauss, William D. Grant, Cornelia E. Farnum, Joseph A. Spadaro, Timothy A. Damron, Sharad Mathur
Publikováno v:
Journal of Histochemistry & Cytochemistry. 52:157-167
This study examined temporal changes in growth plate apoptosis molecules and growth factors in an animal model of radiation injury with and without a radioprotectant. Thirty weanling 5-week Sprague-Dawley rats underwent right knee irradiation with si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a90b99f61ab772a1d5584dca8041e6
https://doi.org/10.1177/002215540405200203
https://doi.org/10.1177/002215540405200203
Autor:
Hannah D. Morgan, Joseph A. Spadaro, Timothy A. Damron, Matthew J. Allen, Judith A. Strauss, Bryan S. Margulies
Publikováno v:
American Journal of Clinical Oncology. 26:e106-e114
At therapeutic levels in pediatric patients, radiation causes damage to the growth plate and contributes to growth deformity and fractures. The purpose of this project was to examine the effects of x-ray irradiation on regional bone mineral density (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c26567fb27e4efb7fec82b4bac2c54
https://doi.org/10.1097/01.coc.0000077934.48841.40
https://doi.org/10.1097/01.coc.0000077934.48841.40
Autor:
Joseph A. Spadaro, Kate O'Hara, Cornelia E. Farnum, Timothy A. Damron, Judith A. Strauss, Bryan S. Margulies
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 85:1302-1313
Background: The availability of radioprotectant drugs that selectively protect normal cells but not tumor cells has rekindled interest in the effects of irradiation on the growth plate. The purpose of the present study was to quantitatively examine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2445b651af0b27b99205c1e93abd09c6
https://doi.org/10.2106/00004623-200307000-00017
https://doi.org/10.2106/00004623-200307000-00017