Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Judith A. Kassis"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1010826 (2023)
engrailed (en) encodes a homeodomain transcription factor crucial for the proper development of Drosophila embryos and adults. Like many developmental transcription factors, en expression is regulated by many enhancers, some of overlapping function,
Externí odkaz:
https://doaj.org/article/9403f02556b44061958a61976787c53c
Publikováno v:
GENETICS.
Polycomb group (PcG) proteins maintain the silenced state of key developmental genes, but how these proteins are recruited to specific regions of the genome is still not completely understood. In Drosophila, PcG proteins are recruited to Polycomb res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::723c0e9cb431347cc308e675aef589ab
https://doi.org/10.1093/genetics/iyad096
https://doi.org/10.1093/genetics/iyad096
Autor:
Maksim Erokhin, J Lesley Brown, Dmitry Lomaev, Nadezhda E Vorobyeva, Liangliang Zhang, Lika V Fab, Marina Yu Mazina, Ivan V Kulakovskiy, Rustam H Ziganshin, Paul Schedl, Pavel Georgiev, Ming-an Sun, Judith A Kassis, Darya Chetverina
Publikováno v:
Nucleic Acids Research.
The Polycomb group (PcG) proteins are fundamental epigenetic regulators that control the repressive state of target genes in multicellular organisms. One of the open questions is defining the mechanisms of PcG recruitment to chromatin. In Drosophila,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::062743a2659b457fb8d9f90e2f937681
https://doi.org/10.1093/nar/gkad336
https://doi.org/10.1093/nar/gkad336
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Beenish Rahat, Matthew T. Van Winkle, Claudia M. Gebert, Jacob A. Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Publikováno v:
Science Advances. 8
Cohesin rings interact with DNA and modulate the expression of thousands of genes. NIPBL loads cohesin onto chromosomes, and WAPL takes it off. Haploinsufficiency for NIPBL causes a developmental disorder, Cornelia de Lange syndrome (CdLS), that is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b293d8a6b083eb1a83207657f877d9f
https://doi.org/10.1126/sciadv.add4136
https://doi.org/10.1126/sciadv.add4136
Autor:
Connor M, Kean, Christopher J, Tracy, Apratim, Mitra, Beenish, Rahat, Matthew T, Van Winkle, Claudia M, Gebert, Jacob A, Noeker, Anne L, Calof, Arthur D, Lander, Judith A, Kassis, Karl, Pfeifer
Publikováno v:
Science advances. 8(48)
Cohesin rings interact with DNA and modulate the expression of thousands of genes. NIPBL loads cohesin onto chromosomes, and WAPL takes it off. Haploinsufficiency for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58b2d824c0513a624e332c8b105545b8
https://pubmed.ncbi.nlm.nih.gov/36449618
https://pubmed.ncbi.nlm.nih.gov/36449618
Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Matthew T Van Winkle, Claudia M Gebert, Jacob Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Cohesin rings interact with DNA and modulate expression of thousands of genes. NIPBL loads cohesin onto chromosomes and WAPL takes it off. Heterozygous mutations in NIPBL lead to a developmental disorder called Cornelia de Lange syndrome. Nipbl heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be961b450c7721577653b98e3e10c09
https://doi.org/10.1101/2022.05.31.493745
https://doi.org/10.1101/2022.05.31.493745
Autor:
Daniel E. Sonenshine, Joao H. F. Pedra, Utpal Pal, Sandip De, Erol Fikrig, Judith A. Kassis, Chrysoula Kitsou
Publikováno v:
Trends Genet
Ticks exist across diverse environments and transmit numerous pathogens. Due to their long and unique life cycles, these arthropods likely evolved robust epigenetic mechanisms that provide sustainable responses and buffers against extreme environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1487d8fc7c1d4f9084a9dadd0851ff10
https://doi.org/10.1016/j.tig.2020.09.012
https://doi.org/10.1016/j.tig.2020.09.012
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006200 (2016)
Polycomb group response elements (PREs) in Drosophila are DNA-elements that recruit Polycomb proteins (PcG) to chromatin and regulate gene expression. PREs are easily recognizable in the Drosophila genome as strong peaks of PcG-protein binding over d
Externí odkaz:
https://doaj.org/article/8484768162f04249994c78e8be7164fb
Autor:
David S Lorberbaum, Andrea I Ramos, Kevin A Peterson, Brandon S Carpenter, David S Parker, Sandip De, Lauren E Hillers, Victoria M Blake, Yuichi Nishi, Matthew R McFarlane, Ason CY Chiang, Judith A Kassis, Benjamin L Allen, Andrew P McMahon, Scott Barolo
Publikováno v:
eLife, Vol 5 (2016)
The Hedgehog signaling pathway is part of the ancient developmental-evolutionary animal toolkit. Frequently co-opted to pattern new structures, the pathway is conserved among eumetazoans yet flexible and pleiotropic in its effects. The Hedgehog recep
Externí odkaz:
https://doaj.org/article/e6841d4cac114d2fb24dfeb50bf17210
Autor:
Natalie D. Gehred, Judith A. Kassis, Sandip De, James B. Jaynes, Miki Fujioka, Fountane W Chan
Publikováno v:
Genetics. 216:689-700
Polycomb group (PcG) proteins are an important group of transcriptional repressors that act by modifying chromatin. PcG target genes are covered by the repressive chromatin mark H3K27me3. Polycomb repressive complex 2 (PRC2) is a multiprotein complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b29702d2d63008099c695e21ff0bb51
https://doi.org/10.1534/genetics.120.303642
https://doi.org/10.1534/genetics.120.303642