Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Judith A. Coppinger"'
Autor:
Kyle Kim, Lance A. Safarta, Wei-Chieh J. Chiang, Judith A. Coppinger, Eun-Jin Lee, Jonathan H. Lin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a misfolded rhodopsin protein that photoreceptors quickly target for degradation by mechan
Externí odkaz:
https://doaj.org/article/49307e443e7d437db7b068f221c30d50
Autor:
Luke Gibbons, Ema Ozaki, Chris Greene, Anne Trappe, Michael Carty, Judith A. Coppinger, Andrew G. Bowie, Matthew Campbell, Sarah L. Doyle
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
SARM1 (sterile alpha and armadillo motif-containing protein) is a highly conserved Toll/IL-1 Receptor (TIR) adaptor with important roles in mediating immune responses. Studies in the brain have shown that SARM1 plays a role in induction of neuronal a
Externí odkaz:
https://doaj.org/article/6e62cc3d245341b18c752e2e3abf4cdc
Autor:
Anne Trappe, Navya Lakkappa, Suzanne Carter, Eugene Dillon, Kieran Wynne, Edward McKone, Paul McNally, Judith A Coppinger
Publikováno v:
Journal of Cystic Fibrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5b2fd5cb0472755eeca680d6fdd975
https://doi.org/10.1016/j.jcf.2023.02.005
https://doi.org/10.1016/j.jcf.2023.02.005
Autor:
Holly Davage, Barry Linnane, Hilary Cassidy, Anne Trappe, Seamas C. Donnelly, Sarah L. Doyle, Edward F. McKone, Judith A. Coppinger, Eugene T. Dillon, Rebecca Reilly, Zivile Useckaite, Jenny Lennon, David Matallanas, Kiva Brennan, Paul McNally, S. Carter, Mark Ward
Publikováno v:
Thorax
RationaleMutations in the cystic fibrosis transmembrane regulator (CFTR) gene form the basis of cystic fibrosis (CF). There remains an important knowledge gap in CF as to how diminished CFTR activity leads to the dominant inflammatory response within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b84b8cae1ec85fdc8241f2e5a5b0113
https://doi.org/10.1136/thoraxjnl-2019-214027
https://doi.org/10.1136/thoraxjnl-2019-214027
Publikováno v:
Thorax
To explore the role of extracellular vesicles (EVs) in chronic lung diseases.EVs are emerging as mediators of intercellular communication and possible diagnostic markers of disease. EVs harbour cargo molecules including RNA, lipids and proteins that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6807d8422595b8cdf20216fb85396a60
https://pubmed.ncbi.nlm.nih.gov/33712504
https://pubmed.ncbi.nlm.nih.gov/33712504
Autor:
Judith A Coppinger, Darren M Hutt, Abbas Razvi, Atanas V Koulov, Sandra Pankow, John R Yates, William E Balch
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37682 (2012)
Protein folding is the primary role of proteostasis network (PN) where chaperone interactions with client proteins determine the success or failure of the folding reaction in the cell. We now address how the Phe508 deletion in the NBD1 domain of the
Externí odkaz:
https://doaj.org/article/c58f48318e9d4af4b9a801a25a808a6e
Autor:
Paul McNally, Edward F. McKone, S. Carter, Judith A. Coppinger, H. Davage, Seamas C. Donnelly, Mark Ward, J. Lennon, Zivile Useckaite, Anne Trappe
Publikováno v:
Journal of Cystic Fibrosis. 19:S43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21eb6be66f9b7c99ab529079c4467465
https://doi.org/10.1016/s1569-1993(20)30302-7
https://doi.org/10.1016/s1569-1993(20)30302-7
Autor:
William M. Gallagher, David Matallanas, Emer Conroy, Amanda McCann, Judith A. Coppinger, Zivile Useckaite, Mark Ward, Tony O'Grady, Darran P. O'Connor, Rebecca Reilly, Eugene M. Dempsey, Anthony J. Chubb, Kate Connor, Alo McGoldrick, Sarah Shields, Elaine W. Kay, Yue Fan
Publikováno v:
Oncotarget
// Sarah Shields 1 , Emer Conroy 1 , Tony O’Grady 5 , Alo McGoldrick 1 , Kate Connor 4 , Mark P. Ward 4 , Zivile Useckaite 4 , Eugene Dempsey 6 , Rebecca Reilly 1 , Yue Fan 1 , Anthony Chubb 4 , David Gomez Matallanas 2, 3 , Elaine W. Kay 5 , Darra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c297538d6a1fb8a2506fa4403f8673f8
Autor:
Rebecca Reilly, Eugene M. Dempsey, Christof Hiebel, Stephen J. Keely, Judith A. Coppinger, Christian Behl, Magdalena S. Mroz, Edward F. McKone, Kieran Wynne
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Deletion of phenylalanine 508 of the cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR) is a major cause of cystic fibrosis (CF), one of the most common inherited childhood diseases. ΔF508 CFTR is a trafficking mutant that is retained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b64faa087ac07d4899e50c86542e66
https://doi.org/10.1038/s41598-017-06588-z
https://doi.org/10.1038/s41598-017-06588-z
Autor:
Judith A. Coppinger, Richard L. Klemke, Xinning Jiang, Ken Fujimura, Sunkyu Choi, Jan Strnadel, Martina P. Pasillas, Jonathan A. Kelber
Publikováno v:
Analytical biochemistry, vol 446, iss 1
The cell cytoskeleton is composed of microtubules, intermediate filaments, and actin that provide a rigid support structure important for cell shape. However, it is also a dynamic signaling scaffold that receives and transmits complex mechanosensing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8277778ad8e7ca8923cc8b72002a4e9b
https://doi.org/10.1016/j.ab.2013.10.025
https://doi.org/10.1016/j.ab.2013.10.025