Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Judith A. Appleton"'
Autor:
Lu Huang, Daniel P Beiting, Nebiat G Gebreselassie, Lucille F Gagliardo, Maura C Ruyechan, Nancy A Lee, James J Lee, Judith A Appleton
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005347 (2015)
It has become increasingly clear that the functions of eosinophils extend beyond host defense and allergy to metabolism and tissue regeneration. These influences have strong potential to be relevant in worm infections in which eosinophils are promine
Externí odkaz:
https://doaj.org/article/7c392441758b4ba8b3f5aed96472985c
Autor:
Kenta Shinoda, Andrea Choe, Kiyoshi Hirahara, Masahiro Kiuchi, Kota Kokubo, Tomomi Ichikawa, Jason S. Hoki, Akane S. Suzuki, Neelanjan Bose, Judith A. Appleton, Raffi V. Aroian, Frank C. Schroeder, Paul W. Sternberg, Toshinori Nakayama
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(9)
Mounting evidence suggests that nematode infection can protect against disorders of immune dysregulation. Administration of live parasites or their excretory/secretory (ES) products has shown therapeutic effects across a wide range of animal models f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc91c4508af1c9acb0a8f70f41f1c009
https://pubmed.ncbi.nlm.nih.gov/35353624
https://pubmed.ncbi.nlm.nih.gov/35353624
Autor:
Lu Huang, Maura C. Ruyechan, Kierstin L. Luber, Nebiat Gebreselassie, Nancy A. Lee, James J. Lee, Judith A. Appleton, Lucille F. Gagliardo
Publikováno v:
The Journal of Immunology. 194:283-290
Eosinophils are versatile cells that regulate innate and adaptive immunity, influence metabolism and tissue repair, and contribute to allergic lung disease. Within the context of immunity to parasitic worm infections, eosinophils are prominent yet hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952737543b6b8b2ea5df320a2dfa43a2
https://doi.org/10.4049/jimmunol.1402219
https://doi.org/10.4049/jimmunol.1402219
Autor:
Judith A. Appleton, Arun Kannan, Avery August, Sonia Mohinta, Nicholas Koylass, Weishan Huang, Lu Huang
Publikováno v:
Scientific Reports
Th1, Th2, Th9 and Th17 cells are conventional CD4+ effector T cells identified as secretors of prototypical cytokines IFNγ, IL4, IL9, and IL-17A respectively. Recently, populations of natural Th17 and Th1 cells (nTh17 and nTh1) with innate-like phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e619d57b2d2fac40c5b8fa3b18a219e
Autor:
Nebiat Gebreselassie, Nancy A. Lee, Maura C. Ruyechan, Lu Huang, Judith A. Appleton, James J. Lee, Lucille F. Gagliardo
Publikováno v:
The Journal of Immunology. 193:4178-4187
Eosinophilia is a feature of the host immune response that distinguishes parasitic worms from other pathogens, yet a discrete function for eosinophils in worm infection has been elusive. The aim of this study was to clarify the mechanism(s) underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7136d767e692602022300ce5a3e56d59
https://doi.org/10.4049/jimmunol.1400852
https://doi.org/10.4049/jimmunol.1400852
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 25:91-98
Measurement of serum immunoglobulin G (IgG) is used for the assessment of passive transfer of immunity in neonatal crias, with an IgG concentration 60%), whereas the IT2 standard consisted of beta and gamma globulins. The discrepant results between a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d196d5810e4d96d34acda2064058edd7
https://doi.org/10.1177/1040638712472182
https://doi.org/10.1177/1040638712472182
Autor:
Lu Huang, Judith A. Appleton
Publikováno v:
Trends in parasitology. 32(10)
Eosinophilia is a central feature of the host response to helminth infection. Larval stages of parasitic worms are killed in vitro by eosinophils in the presence of specific antibodies or complement. These findings established host defense as the par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea06057e32f279cb442593ee0da3e6b
https://pubmed.ncbi.nlm.nih.gov/27262918
https://pubmed.ncbi.nlm.nih.gov/27262918
Publikováno v:
Immunity to Parasitic Infection. :275-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8199be9f24cbddfacb057b0a991f75e
https://doi.org/10.1002/9781118393321.ch15
https://doi.org/10.1002/9781118393321.ch15
Autor:
Nebiat Gebreselassie, Nancy A. Lee, Judith A. Appleton, Valeria Fabre, James J. Lee, Andrew R. Moorhead, Lucille F. Gagliardo
Publikováno v:
The Journal of Immunology. 188:417-425
Eosinophils play important roles in regulation of cellular responses under conditions of homeostasis or infection. Intestinal infection with the parasitic nematode, Trichinella spiralis, induces a pronounced eosinophilia that coincides with establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0defede3f567e41ab0cd5432ae863ea
https://doi.org/10.4049/jimmunol.1101980
https://doi.org/10.4049/jimmunol.1101980
Autor:
Shiaw-Pyng Yang, Judith A. Appleton, Yong Yin, Xu Zhang, Douglas P. Jasmer, Elaine R. Mardis, Sahar Abubucker, Dante S. Zarlenga, Zhengyuan Wang, Sandra W. Clifton, James P. McCarter, Kym Hallsworth-Pepin, John Martin, Wesley C. Warren, Richard K. Wilson, Patrick Minx, Robert S. Fulton, Makedonka Mitreva, Lucinda Fulton, Veena Bhonagiri, Christina M. Taylor
Publikováno v:
Nature genetics
Genome evolution studies for the phylum Nematoda have been limited by focusing on comparisons involving Caenorhabditis elegans. We report a draft genome sequence of Trichinella spiralis, a food-borne zoonotic parasite, which is the most common cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe84db1fcd0dfba4b8dae1c39bceb55
https://doi.org/10.1038/ng.769
https://doi.org/10.1038/ng.769