Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Judith A, Stolwijk"'
Autor:
Judith A. Stolwijk, Joachim Wegener
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Specific intracellular manipulation of animal cells is a persistent goal in experimental cell biology. Such manipulations allow precise and targeted interference with signaling cascades, metabolic pathways, or bi-molecular interactions for s
Externí odkaz:
https://doaj.org/article/b40df4c446e64c679044fd72f70e6c53
Publikováno v:
Methods in cell biology. 169
G protein-coupled receptors (GPCRs) are among the most heavily addressed drug targets in medicinal chemistry and pharmacology. The screening for new agonists or antagonists has been largely based on genetically engineered cells overexpressing the rec
Autor:
Antje J. Baeumner, Judith Heider, Nongnoot Wongkaew, Joachim Wegener, Marcel Simsek, Stephan Schreml, Judith A. Stolwijk
Publikováno v:
ACS applied bio materials. 3(8)
Mats of cytocompatible polymer fibers are needed as scaffolds in tissue engineering or as wound healing supports. Most recently, they have emerged as matrix-material to allow for in situ chemo- and biosensing inside intact tissue fragments or surroga
Publikováno v:
Biomolecular Interactions Part B ISBN: 9780128233535
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00f339f1e77c0067ac94c73beef405e6
https://doi.org/10.1016/bs.mcb.2021.12.005
https://doi.org/10.1016/bs.mcb.2021.12.005
Autor:
Joachim Wegener, Judith A. Stolwijk
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Specific intracellular manipulation of animal cells is a persistent goal in experimental cell biology. Such manipulations allow precise and targeted interference with signaling cascades, metabolic pathways, or bi-molecular interactions for subsequent
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
The proton-sensing GPCRs (pH-GPCRs) GPR4 (GPR19), TDAG8 (GPR65, T-cell death associated gene 8), OGR1 (GPR68, ovarian cancer GPCR1), and G2A (GPR132, G2 accumulation protein) are involved in sensing and transducing changes in extracellular pH (pHe).
Autor:
Guenther Bernhardt, Joachim Wegener, Peter Gmeiner, Christian Kade, Anne-Kathrin Mildner, Michael Skiba, Armin Buschauer, Judith A. Stolwijk, Harald Huebner
Publikováno v:
Journal of visualized experiments : JoVE. (156)
Label-free impedance-based assays are increasingly used to non-invasively study ligand-induced GPCR activation in cell culture experiments. The approach provides real-time cell monitoring with a device-dependent time resolution down to several tens o
Autor:
Anaïs Nassios, Judith A. Stolwijk, Thiha Aung, Joachim Wegener, Silke Haerteis, Antje J Bäumner, Kirsten Ackermann, Lisa Sauer, Stephan Schreml
Solid tumors exhibit an inversed pH gradient with increased intracellular pH (pH(i)) and decreased extracellular pH (pH(e)). This inside-out pH gradient is generated via sodium/hydrogen antiporter 1, vacuolar-type H + ATPases, monocarboxylate transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa19e013302e72a0904e314acfddd06
Autor:
Peter Gmeiner, Christian Kade, Michael Skiba, Joachim Wegener, Armin Buschauer, Judith A. Stolwijk, Harald Hübner, Guenther Bernhardt
Label-free, holistic assays, monitoring, for example, the impedance of cells on electrodes, are gaining increasing popularity in the evaluation of G-protein-coupled receptor (GPCR) ligands. It is the strength of these approaches to provide the integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ccfd360be6859535b12c9376b83051
https://publica.fraunhofer.de/handle/publica/257813
https://publica.fraunhofer.de/handle/publica/257813
Autor:
Joachim Wegener, Judith A. Stolwijk
Impedance-based monitoring of adherent cells has gained increasing acceptance in many areas of biomedical research and drug discovery, as it provides a noninvasive and label-free experimental tool to continuously monitor cell behavior in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::623491d39a5c6dbe6c11e541b05b6217
https://doi.org/10.1007/11663_2019_7
https://doi.org/10.1007/11663_2019_7