Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Judith, Wackerlig"'
Autor:
Predrag Kalaba, Katharina Pacher, Philip John Neill, Vladimir Dragacevic, Martin Zehl, Judith Wackerlig, Michael Kirchhofer, Simone B. Sartori, Hubert Gstach, Shima Kouhnavardi, Anna Fabisikova, Matthias Pillwein, Francisco Monje-Quiroga, Karl Ebner, Alexander Prado-Roller, Nicolas Singewald, Ernst Urban, Thierry Langer, Christian Pifl, Jana Lubec, Johann Jakob Leban, Gert Lubec
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1415 (2023)
The high structural similarity, especially in transmembrane regions, of dopamine, norepinephrine, and serotonin transporters, as well as the lack of all crystal structures of human isoforms, make the specific targeting of individual transporters rath
Externí odkaz:
https://doaj.org/article/206825143bfe4497bebe4460b140ad5d
Autor:
István Gyertyán, Jana Lubec, Alíz Judit Ernyey, Christopher Gerner, Ferenc Kassai, Predrag Kalaba, Kata Kozma, Iva Cobankovic, Gábor Brenner, Judith Wackerlig, Eva Franschitz, Ernst Urban, Thierry Langer, Jovana Malikovic, Gert Lubec
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The lack of novel cognitive enhancer drugs in the clinic highlights the prediction problems of animal assays. The objective of the current study was to test a putative cognitive enhancer in a rodent cognitive test system with improved transl
Externí odkaz:
https://doaj.org/article/8de4d2688112472988785def180b9487
Autor:
Jana Lubec, Ahmed M. Hussein, Predrag Kalaba, Daniel Daba Feyissa, Edgar Arias-Sandoval, Anita Cybulska-Klosowicz, Mekite Bezu, Tamara Stojanovic, Volker Korz, Jovana Malikovic, Nilima Y. Aher, Martin Zehl, Vladimir Dragacevic, Johann Jakob Leban, Claudia Sagheddu, Judith Wackerlig, Marco Pistis, Merce Correa, Thierry Langer, Ernst Urban, Harald Höger, Gert Lubec
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 467 (2023)
The worldwide increase in cognitive decline, both in aging and with psychiatric disorders, warrants a search for pharmacological treatment. Although dopaminergic treatment approaches represent a major step forward, current dopamine transporter (DAT)
Externí odkaz:
https://doaj.org/article/31e9c20c5680455db70326abd3c16764
Autor:
Martina Oberhofer, Judith Wackerlig, Martin Zehl, Havva Büyük, Jia Jian Cao, Alexander Prado-Roller, Ernst Urban, Sergey B. Zotchev
Publikováno v:
ACS Omega, Vol 6, Iss 3, Pp 2184-2191 (2021)
Externí odkaz:
https://doaj.org/article/c165f01d9d6a47cb8655d63520cdb9a6
Autor:
Shima Kouhnavardi, Alev Ecevitoglu, Vladimir Dragačević, Fabrizio Sanna, Edgar Arias-Sandoval, Predrag Kalaba, Michael Kirchhofer, Jana Lubec, Marco Niello, Marion Holy, Martin Zehl, Matthias Pillwein, Judith Wackerlig, Rita Murau, Andrea Mohrmann, Kathryn R. Beard, Harald H. Sitte, Ernst Urban, Claudia Sagheddu, Marco Pistis, Roberto Plasenzotti, John D. Salamone, Thierry Langer, Gert Lubec, Francisco J. Monje
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 881 (2022)
Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter, modulates key behavioral and neurological processes in young and senescent brains, including motricity, sleep, attention, emotion, learning and memory, and social and re
Externí odkaz:
https://doaj.org/article/ea4993ee98834d4a80993681061f26a1
Autor:
Judith Wackerlig, Harald C. Köfeler, Volker Korz, Ahmed M. Hussein, Daniel D. Feyissa, Harald Höger, Ernst Urban, Thierry Langer, Gert Lubec, Jana Lubec
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Lipids play a major role for several brain functions, including cognition and memory. There is a series of work on individual lipids showing involvement in memory mechanisms, a concise lipidome was not reported so far. Moreover, there is no evidence
Externí odkaz:
https://doaj.org/article/8ca204f0b91048ea9dedfa9d37913337
Autor:
Renee A. Rotolo, Vladimir Dragacevic, Predrag Kalaba, Ernst Urban, Martin Zehl, Alexander Roller, Judith Wackerlig, Thierry Langer, Marco Pistis, Maria Antonietta De Luca, Francesca Caria, Rebecca Schwartz, Rose E. Presby, Jen-Hau Yang, Shanna Samels, Merce Correa, Gert Lubec, John D. Salamone
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Animal studies of effort-based choice behavior are being used to model effort-related motivational dysfunctions in humans. With these procedures, animals are offered a choice between high-effort instrumental actions leading to highly valued reinforce
Externí odkaz:
https://doaj.org/article/1dbdc85072d848bb9671ac0498d5b877
Autor:
Nasim Sanadgol, Judith Wackerlig
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 831 (2020)
Cancer therapy is still a huge challenge, as especially chemotherapy shows several drawbacks like low specificity to tumor cells, rapid elimination of drugs, high toxicity and lack of aqueous solubility. The combination of molecular imprinting techno
Externí odkaz:
https://doaj.org/article/075b8a876b7c40d88466f83e936cc702
Autor:
Stefan Poschner, Alexandra Maier-Salamon, Martin Zehl, Judith Wackerlig, Daniel Dobusch, Anastasia Meshcheryakova, Diana Mechtcheriakova, Theresia Thalhammer, Bettina Pachmann, Walter Jäger
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The role of resveratrol (RES) in preventing breast cancer is controversial, as low concentrations may stimulate the proliferation of estrogen-receptor alpha positive (ERα+) breast cancer cells. As metabolism is the key factor in altering cellular es
Externí odkaz:
https://doaj.org/article/4a2295e611124c70883958c374688aa6
Autor:
Marija Ilic, Jana Lubec, Alexander Roller, Vladimir Dragačević, Jovana Malikovic, Shima Kouhnavardi, Johann Leban, Roberto Plasenzotti, Simone B. Sartori, Thierry Langer, Predrag Kalaba, Marco Pistis, Judith Wackerlig, Christian Pifl, Daniel Daba Feyissa, Martin Zehl, Karl Ebner, Nicolas Singewald, Ernst Urban, Claudia Sagheddu, Arthur Garon, Mohamed H. Kotob, Ahmed M. Hussein, Rasha Refaat Mahmmoud, Francisco J. Monje, Natalie Gajic, Anita Cybulska-Klosowicz, Oliver Wieder, Gert Lubec, Harald H. Sitte, Volker Korz
Publikováno v:
Molecular Psychiatry. 26:7076-7090
Aging-related neurological deficits negatively impact mental health, productivity, and social interactions leading to a pronounced socioeconomic burden. Since declining brain dopamine signaling during aging is associated with the onset of neurologica