Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Judith, Thoma"'
Autor:
Marco Kunzelmann, Judith Thoma, Sabrina Laibacher, Joey M. Studts, Beate Presser, Julia Spitz
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Multivariate interactions between process parameters can heavily impact product quality and process performance in biopharmaceutical manufacturing processes. Thus, multivariate interactions should be identified and appropriately controlled.
Externí odkaz:
https://doaj.org/article/a2a9108bf33d4994a31fc88e54d089d8
Publikováno v:
AAPS Open, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Objective Random effects are often neglected when defining the control strategy for a biopharmaceutical process. In this article, we present a case study that highlights the importance of considering the variance introduced by random effects
Externí odkaz:
https://doaj.org/article/133383de0df840e58d52ec27c56e5a02
Autor:
Lixiazi He, Christian Arnold, Judith Thoma, Christian Rohde, Maksim Kholmatov, Swati Garg, Cheng‐Chih Hsiao, Linda Viol, Kaiqing Zhang, Rui Sun, Christina Schmidt, Maike Janssen, Tara MacRae, Karin Huber, Christian Thiede, Josée Hébert, Guy Sauvageau, Julia Spratte, Herbert Fluhr, Gabriela Aust, Carsten Müller‐Tidow, Christof Niehrs, Gislene Pereira, Jörg Hamann, Motomu Tanaka, Judith B Zaugg, Caroline Pabst
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp 1-22 (2022)
Abstract The heterogeneous response of acute myeloid leukemia (AML) to current anti‐leukemic therapies is only partially explained by mutational heterogeneity. We previously identified GPR56 as a surface marker associated with poor outcome across g
Externí odkaz:
https://doaj.org/article/268002c07dd34175a0c516fb03b86c27
Autor:
Esther Kimmle, Zahra Hajian Foroushani, Stephan Keppler, Judith Thoma, Kentaro Hayashi, Akihisa Yamamoto, Martin Bastmeyer, Motomu Tanaka
Publikováno v:
Frontiers in Physics, Vol 10 (2022)
The self-renewal and lineage-specific differentiation of stem cells are regulated by interactions with their microenvironments, called stem cell niche. Stem cells receive both biochemical and biophysical cues from their niche, which leads to the acti
Externí odkaz:
https://doaj.org/article/264d673bd634417da567ae66347cfd7e
Autor:
Motomu Tanaka, Atsushi Takahara, Esther Kimmle, Akihisa Yamamoto, Judith Thoma, Bruno Demé, Ryohei Ishige, Yuji Higaki
Publikováno v:
'Polymer Journal ', vol: 54, pages: 57-65 (2022)
Comb-like polymers with pendant-like perfluorocarbon side chains self-assemble into smectic lamellae and have been extensively used as water-repellent, hydrophobic coating materials characterized by large water contact angles (θ > 120°). As poly(pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf4ba2f73b53e4a5954a1dec270b69b
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ILL:31221
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ILL:31221
Autor:
Motomu Tanaka, Judith Thoma, Laura Poisa-Beiro, Patrick Wuchter, Volker Eckstein, Sascha Dietrich, Caroline Pabst, Carsten Müller-Tidow, Takao Ohta, Anthony D. Ho
Publikováno v:
Cells & Development. 174:203845
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59671e33c4cf937a851f9b094753e12
https://doi.org/10.1016/j.cdev.2023.203845
https://doi.org/10.1016/j.cdev.2023.203845
Autor:
Yuriy Chushkin, Judith Thoma, Oleg Konovalov, Wasim Abuillan, Federico Amadei, Esther Kimmle, Julian Czajor, Motomu Tanaka, Akihisa Yamamoto
Publikováno v:
The Journal of Physical Chemistry B. 124:8937-8942
As manifested in biological cell membranes, the confinement of chemical reactions at the 2D interfaces significantly improves the reaction efficacy. The interface between two liquid phases is used in various key processes in industries, such as in fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c4f01d43cbe09da0d3266ed545cba9
https://doi.org/10.1021/acs.jpcb.0c07056
https://doi.org/10.1021/acs.jpcb.0c07056
Autor:
Christine Lansche, Cecilia P. Sanchez, Benjamin Fröhlich, Peter Cloetens, Judith Thoma, Yang Yang, Julian Czajor, Michael Lanzer, Motomu Tanaka
Publikováno v:
Analytical Chemistry. 92:5765-5771
While there is ample evidence suggesting that carriers of heterozygous hemoglobin S and C are protected from life-threatening malaria, little is known about the underlying biochemical mechanisms at the single cell level. Using nanofocused scanning X-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b167d016153cc17a4e933dc2f49812b0
https://doi.org/10.1021/acs.analchem.9b05111
https://doi.org/10.1021/acs.analchem.9b05111
Autor:
Judith Thoma, Taichi Habe, Oleg Konovalov, Ippei Furikado, Wasim Abuillan, Shigeto Inoue, Klaus Brandenburg, Motomu Tanaka, Akihisa Yamamoto, Stefan H. E. Kaufmann, Simone Gierlich, Thomas Gutsmann
Publikováno v:
'Scientific Reports ', vol: 10, pages: 12302-1-12302-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Antimicrobial resistance is a major threat to public health. Although many commercial sanitisers contain a combination of cationic surfactants and aromatic alcohols, the physical mechanisms where these two substances bind to or how they disturb bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849518a1632a6b3e3c046233b42e2b74
https://doi.org/10.1038/s41598-020-69064-1
https://doi.org/10.1038/s41598-020-69064-1
Autor:
Anne-Claude Gavin, Akihisa Yamamoto, Georg F. Hoffmann, Sven W. Sauer, Vladimir Benes, Laura Poisa-Beiro, Natalie Romanov, Judith Thoma, Anthony D. Ho, Motomu Tanaka, Jonathan J M Landry, Simon Raffel, Peer Bork, Volker Eckstein
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol. 10, No 1 (2020) P. 11597
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol. 10, No 1 (2020) P. 11597
Inspired by recent proteomic data demonstrating the upregulation of carbon and glycogen metabolism in aging human hematopoietic stem and progenitor cells (HPCs, CD34+ cells), this report addresses whether this is caused by elevated glycolysis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824543b7b918f549bd6e5fd29d3e5001
https://doi.org/10.1038/s41598-020-68396-2
https://doi.org/10.1038/s41598-020-68396-2