Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Judith, Kraiczy"'
Autor:
Brandon T. Wesley, Alexander D. B. Ross, Daniele Muraro, Zhichao Miao, Sarah Saxton, Rute A. Tomaz, Carola M. Morell, Katherine Ridley, Ekaterini D. Zacharis, Sandra Petrus-Reurer, Judith Kraiczy, Krishnaa T. Mahbubani, Stephanie Brown, Jose Garcia-Bernardo, Clara Alsinet, Daniel Gaffney, Dave Horsfall, Olivia C. Tysoe, Rachel A. Botting, Emily Stephenson, Dorin-Mirel Popescu, Sonya MacParland, Gary Bader, Ian D. McGilvray, Daniel Ortmann, Fotios Sampaziotis, Kourosh Saeb-Parsy, Muzlifah Haniffa, Kelly R. Stevens, Matthias Zilbauer, Sarah A. Teichmann, Ludovic Vallier
Publikováno v:
Nature Cell Biology. 24:1487-1498
The liver has been studied extensively due to the broad number of diseases affecting its vital functions. However, therapeutic advances have been hampered by the lack of knowledge concerning human hepatic development. Here, we addressed this limitati
Autor:
Judith Kraiczy, Matthias Zilbauer
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The intestinal epithelium forms the inner layer of the human intestine and serves a wide range of diverse functions. Its constant exposure to a vast amount of complex microbiota highlights the critical interface that this single-cell layer forms betw
Externí odkaz:
https://doaj.org/article/6de516c646e249fcbab6c707672c4991
Autor:
Neil McCarthy, Guodong Tie, Shariq Madha, Ruiyang He, Judith Kraiczy, Adrianna Maglieri, Ramesh A. Shivdasani
Publikováno v:
Developmental Cell. 58:550-564.e6
Autor:
Judith Kraiczy, Neil McCarthy, Ermanno Malagola, Guodong Tie, Shariq Madha, Dario Boffelli, Daniel E. Wagner, Timothy C. Wang, Ramesh A. Shivdasani
Publikováno v:
Cell Stem Cell. 30:433-449.e8
Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D Edgar, Francesca Perrone, April R Foster, Felicity Payne, Sophia Lewis, Komal M Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O Hensel, Rebecca Harris, D. Leanne Jones, Daniel R Zerbino, Matthias Zilbauer
Background & AimsHuman intestinal epithelial organoids (IEO) are a powerful tool to model major aspects of intestinal development, health and diseases, as patient derived cultures retain many features found in-vivo. A necessary aspect of the organoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c70d852eae9f9e5b1e0975ac83948df8
https://doi.org/10.1101/2022.04.25.489354
https://doi.org/10.1101/2022.04.25.489354
Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D. Edgar, Francesca Perrone, April R. Foster, Felicity Payne, Sophia Lewis, Komal M. Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O. Hensel, Rebecca Harris, D. Leanne Jones, Daniel R. Zerbino, Matthias Zilbauer
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 14(6)
BACKGROUND & AIMS: Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived cultures retain many features found in vivo. A necessary aspect of the
Publikováno v:
Nature Cell Biology. 22:1033-1041
Intestinal stem and progenitor cells replicate and differentiate in distinct compartments, influenced by Wnt, BMP, and other subepithelial cues. The cellular sources of these signals were long obscure because intestinal mesenchyme was insufficiently
Autor:
Neil McCarthy, Guodong Tie, Shariq Madha, Judith Kraiczy, Adrianna Maglieri, Ramesh Shivdasani
Publikováno v:
SSRN Electronic Journal.
Autor:
Adrianna Maglieri, Judith Kraiczy, Shariq Madha, Neil McCarthy, Ramesh A. Shivdasani, Guodong Tie
Wnt and Rspondin (RSPO) signaling triggers proliferation, and bone morphogenetic protein inhibitors (BMPi) impede differentiation, of intestinal stem cells (ISCs). Here we report that the functional ISC niche is a complex, multi-layered mesenchymal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8761ccac5ece0a6787278831b3087ded
https://doi.org/10.1101/2021.09.28.462142
https://doi.org/10.1101/2021.09.28.462142
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
Autor:
Qiao Zhou, Jason R. Spence, Ramesh A. Shivdasani, Sean Houghton, Xiaofeng Huang, Michael P. Verzi, Kristian Helin, Ellen Scherl, Shahin Rafii, Ying Lan, Jiaoyue Zhang, Wei Gu, Brad W. Warner, Emily J. Onufer, Sezin Dagdeviren, Richard T. Lee, Charles Ng, Yaohui Nie, Hua Wang, Pratik N.P. Singh, Oscar Pellon-Cardenas, Judith Kraiczy, Kushal K. Banerjee, Randy S. Longman, David Redmond
Publikováno v:
Cell Stem Cell
Adult stem cells maintain regenerative tissue structure and function by producing tissue-specific progeny, but the factors that preserve their tissue identities are not well understood. The small and large intestines differ markedly in cell compositi