Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Judith, Goncalves"'
Autor:
Paule Bénit, Judith Goncalves, Riyad El Khoury, Malgorzata Rak, Judith Favier, Anne-Paule Gimenez-Roqueplo, Pierre Rustin
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1788 (2022)
Research focused on succinate dehydrogenase (SDH) and its substrate, succinate, culminated in the 1950s accompanying the rapid development of research dedicated to bioenergetics and intermediary metabolism. This allowed researchers to uncover the imp
Externí odkaz:
https://doaj.org/article/fb1bca52e480479c8de00d10783417b0
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Figure 1 - Supplementary Figure 2 - Supplementary Figure 3 - Supplementary Figure 4 - Supplementary Figure 5 - Supplementary Figure 6 - Supplementary Table 1 - Supplementary Table 2 - Supplementary Table 3 - Supplementary Table 4 - Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa5c66a17bcd42509bb7c99b59f814
https://doi.org/10.1158/0008-5472.22428819
https://doi.org/10.1158/0008-5472.22428819
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Succinate dehydrogenase is a key enzyme in the tricarboxylic acid cycle and the electron transport chain. All four subunits of succinate dehydrogenase are tumor suppressor genes predisposing to paraganglioma, but only mutations in the SDHB subunit ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8344fed531abd70c4e2067dd3f8dac8
https://doi.org/10.1158/0008-5472.c.6513153.v1
https://doi.org/10.1158/0008-5472.c.6513153.v1
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Table 2 Related to Figure 2. Differentially methylated gene-based features in Sdhb-/- versus Sdhd-/- imCCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b04c08f42c8e0660b2c6f91c099c84
https://doi.org/10.1158/0008-5472.22428816.v1
https://doi.org/10.1158/0008-5472.22428816.v1
Autor:
Rebecca L. Hindshaw, Gareth G. Lavery, Baksho Kaul, Judith Goncalves, Cristina Escribano-Gonzalez, Katarína Kľučková, Lisa Vettore, Alpesh Thakker, Judith Favier, Daniel A. Tennant, Jacqueline L. E. Tearle
Publikováno v:
The FASEB Journal. 34:303-315
Mutations in succinate dehydrogenase (SDH) lead to the development of tumors in a restricted subset of cell types, including chromaffin cells and paraganglia. The molecular basis for this specificity is currently unknown. We show that loss of SDH act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc829738310efe14b4a3a0ff1c3f3e4e
https://doi.org/10.1096/fj.201901456r
https://doi.org/10.1096/fj.201901456r
Autor:
Fatima Mechta-Grigoriou, Judith Goncalves, Alpesh Thakker, Judith Favier, Charlotte Lussey-Lepoutre, Theodora J. Stewart, Alexander P. Morrell, Daniel A. Tennant, Katarina Kluckova, Lisa Vettore, Sebastian Müller, Paule Bénit, Eric Letouzé, Sophie Moog, Anne-Paule Gimenez-Roqueplo, Jennie Roberts, Géraldine Gentric, Cynthia L. Andoniadou, Aurélie Morin, Raphaël Rodriguez
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2021, 81 (13), pp.3480-3494. ⟨10.1158/0008-5472.CAN-20-2936⟩
Cancer Research, 2021, ⟨10.1158/0008-5472.CAN-20-2936⟩
Cancer Research, American Association for Cancer Research, 2021, ⟨10.1158/0008-5472.CAN-20-2936⟩
Cancer Research, American Association for Cancer Research, 2021, 81 (13), pp.3480-3494. ⟨10.1158/0008-5472.CAN-20-2936⟩
Cancer Research, 2021, ⟨10.1158/0008-5472.CAN-20-2936⟩
Cancer Research, American Association for Cancer Research, 2021, ⟨10.1158/0008-5472.CAN-20-2936⟩
Succinate dehydrogenase is a key enzyme in the tricarboxylic acid cycle and the electron transport chain. All four subunits of succinate dehydrogenase are tumor suppressor genes predisposing to paraganglioma, but only mutations in the SDHB subunit ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddbf8f6a999762a6115d769516d138a
https://hal.archives-ouvertes.fr/hal-03365516
https://hal.archives-ouvertes.fr/hal-03365516
Publikováno v:
Current opinion in oncology. 33(1)
Purpose of review Pheochromocytomas and paragangliomas (PPGL) display a strong genetic determinism with 40% of inherited forms. The purpose of this review is to provide an update on current knowledge on adult forms of hereditary PPGL and their manage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df27e27391f51753edb947da3f27211
https://pubmed.ncbi.nlm.nih.gov/33186184
https://pubmed.ncbi.nlm.nih.gov/33186184
Publikováno v:
Cell and Tissue Research. 372:379-392
Paragangliomas and pheochromocytomas are rare neuroendocrine tumors characterized by a large spectrum of hereditary predisposition. Based on gene expression profiling classification, they can be classically assigned to either a hypoxic/angiogenic clu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c56e3b7e1cc0dff9d00087c7f2f12c0b
https://doi.org/10.1007/s00441-018-2797-y
https://doi.org/10.1007/s00441-018-2797-y
Autor:
Svenja Nölting, Judith Goncalves, Judith Favier, Gerald Spöttl, Petra Rank, Barbara Klink, Michael Lauseker, Felix Beuschlein, German Rubinstein, Graeme Eisenhofer, Stefan R. Bornstein, Julian Maurer, Maria Fankhauser, M. Orth, Nicole Bechmann, Thomas Knösel, Doreen William, Laura Gieldon, Christoph J. Auernhammer, Martin Fassnacht, Karel Pacak, Elke Tatjana Aristizabal Prada, Ashley B. Grossman, Christine Spitzweg, Christian G. Ziegler, Martin Reincke
There are no officially approved therapies for metastatic pheochromocytomas apart from ultratrace 131I-metaiodbenzylguanidine therapy, which is approved only in the United States. We have, therefore, investigated the antitumor potential of molecular-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d188663d582d0ef44aaa693aca47d672
https://doi.org/10.5167/uzh-173847
https://doi.org/10.5167/uzh-173847
Autor:
Anne-Paule Gimenez-Roqueplo, Judith Favier, Luis Jaime Castro-Vega, Charlotte Lussey-Lepoutre, Judith Goncalves
Publikováno v:
Annales d'Endocrinologie
Annales d'Endocrinologie, Elsevier Masson, 2019, 80, pp.159-162. ⟨10.1016/j.ando.2019.04.003⟩
Annales d'Endocrinologie, Elsevier Masson, 2019, 80, pp.159-162. ⟨10.1016/j.ando.2019.04.003⟩
Metastatic pheochromocytoma/paraganglioma (PPGL) represents a major clinical challenge due to limitations in accurate diagnostic tools and effective treatments. Currently, patients classified at high-risk by means of clinical, biochemical and genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40583e06d129f1a92e88d9c4eff7fdfd
https://pubmed.ncbi.nlm.nih.gov/31053249
https://pubmed.ncbi.nlm.nih.gov/31053249