Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Judite R. M. Coimbra"'
Autor:
Judite R. M. Coimbra, Salete J. Baptista, Teresa C. P. Dinis, Maria M. C. Silva, Paula I. Moreira, Armanda E. Santos, Jorge A. R. Salvador
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 535 (2020)
The treatment options for a patient diagnosed with Alzheimer’s disease (AD) are currently limited. The cerebral accumulation of amyloid-β (Aβ) is a critical molecular event in the pathogenesis of AD. When the amyloidogenic β-secretase (BACE1) is
Externí odkaz:
https://doaj.org/article/b956f6a9c4874660b56c184c163a53d9
Autor:
Judite R. M. Coimbra, Daniela F. F. Marques, Salete J. Baptista, Cláudia M. F. Pereira, Paula I. Moreira, Teresa C. P. Dinis, Armanda E. Santos, Jorge A. R. Salvador
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Alzheimer's disease (AD) is a severe neurodegenerative disorder and the most common type of dementia in the elderly. The clinical symptoms of AD include a progressive loss of memory and impairment of cognitive functions interfering with daily life ac
Externí odkaz:
https://doaj.org/article/781cd9b1ae714b2086ee1e78dee73829
Autor:
Armanda E. Santos, Paula I. Moreira, M. Manuel Cruz Silva, Salete J. Baptista, Jorge A. R. Salvador, Judite R M Coimbra, Teresa C.P. Dinis
Publikováno v:
Biomolecules
Volume 10
Issue 4
Biomolecules, Vol 10, Iss 535, p 535 (2020)
Volume 10
Issue 4
Biomolecules, Vol 10, Iss 535, p 535 (2020)
The treatment options for a patient diagnosed with Alzheimer&rsquo
s disease (AD) are currently limited. The cerebral accumulation of amyloid-&beta
(A&beta
) is a critical molecular event in the pathogenesis of AD. When the amyloidogen
s disease (AD) are currently limited. The cerebral accumulation of amyloid-&beta
(A&beta
) is a critical molecular event in the pathogenesis of AD. When the amyloidogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5c07902bd074469297ce4c967fb906
Autor:
Paula I. Moreira, Pedro J. M. Sobral, Armanda E. Santos, Judite R M Coimbra, Jorge Ar Salvador
Publikováno v:
Future medicinal chemistry. 11(24)
A diverse range of N-terminally truncated and modified forms of amyloid-β (Aβ) oligomers have been discovered in Alzheimer’s disease brains, including the pyroglutamate-Aβ (AβpE3). AβpE3 species are shown to be more neurotoxic when compared wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b726d321bd4da23e1ce4139228e697a1
https://pubmed.ncbi.nlm.nih.gov/31838899
https://pubmed.ncbi.nlm.nih.gov/31838899