Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Judit Wefer"'
Autor:
Asa Andersson, Magnus Isaksson, Judit Wefer, Anna Norling, Amilcar Flores-Morales, Fredrik Rorsman, Olle Kämpe, Robert A Harris, Anna Lobell
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3682 (2008)
BACKGROUND: We have previously shown that vaccination with DNA encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (MOG)(91-108) (pMOG) suppresses MOG(91-108)-induced rat Experimental Autoimmune Encephalomyelitis (EAE), a model
Externí odkaz:
https://doaj.org/article/81ac7dd80c03478c82629d2ba472e392
Publikováno v:
Journal of Neuroimmunology. 149:66-76
DNA vaccines encoding encephalitogenic peptides protect against subsequent development of rat experimental autoimmune encephalomyelitis (EAE) through unknown mechanisms. We investigated immune cell phenotypes at different time points after DNA vaccin
Autor:
Katrien L. de Graaf, Robert Weissert, Hans Lassmann, Sana Eltayeb, Tomas Olsson, Judit Wefer, Anna Lobell, Maria K. Storch, Hans Wigzell
Publikováno v:
The Journal of Immunology. 170:1806-1813
Vaccination with DNA encoding a myelin basic protein peptide suppresses Lewis rat experimental autoimmune encephalomyelitis (EAE) induced with the same peptide. Additional myelin proteins, such as myelin oligodendrocyte glycoprotein (MOG), may be imp
Publikováno v:
Journal of leukocyte biology. 76(6)
Rodents typically demonstrate strain-specific susceptibilities to induced autoimmune models such as experimental arthritis and encephalomyelitis. A common feature of the local pathology of these diseases is an extensive infiltration of activated macr
Autor:
Robert A. Harris, Khairul Bariah Abdul-Majid, Hans Lassmann, Judit Wefer, Tomas Olsson, Christine Stadelmann, Andreas Stefferl
Publikováno v:
Journal of neuroimmunology. 141(1-2)
Experimental autoimmune encephalomyelitis (EAE) was induced with myelin oligodendrocyte glycoprotein (MOG(1-125)) in CD4(-/-) and CD8(-/-) DBA/1 mice. Both gene-deleted mice developed clinical signs of EAE, albeit milder than in wild-type mice, sugge
Publikováno v:
European journal of immunology. 33(6)
To prevent an organism from developing autoimmunity the body limits the number of autoreactive cells through thymic negative selection and regulates their activity through induction of suppressor T cells. Development of antigen-specific therapies pro
Publikováno v:
Scandinavian Journal of Immunology
DNA vaccine coding for the encephalitogenic peptide MOG91-108 protects LEW.1AV1 from subsequent development of experimental autoimmune encephalomyelitis (EAE). Protection is associated with a type 1 immune response and is dependent on the presence of