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pro vyhledávání: '"Judit P Banath"'
Autor:
Pamela Kanellis, Mark Gagliardi, Judit P Banath, Rachel K Szilard, Shinichiro Nakada, Sarah Galicia, Frederic D Sweeney, Diane C Cabelof, Peggy L Olive, Daniel Durocher
Publikováno v:
PLoS Genetics, Vol 3, Iss 8, p e134 (2007)
Genome instability is a hallmark of cancer cells. One class of genome aberrations prevalent in tumor cells is termed gross chromosomal rearrangements (GCRs). GCRs comprise chromosome translocations, amplifications, inversions, deletion of whole chrom
Externí odkaz:
https://doaj.org/article/543d1111c50c4b1cac209eefebc8af72
Publikováno v:
Radiation Research. 151:550
X-ray-induced DNA base damage can be detected using endonuclease III and formamidopyrimidine-glycosylase, which create DNA strand breaks at enzyme-sensitive sites. Strand breaks can then be measured with excellent sensitivity using the alkaline comet
Publikováno v:
Radiation Research. 142:144
Removal of histones and other nuclear proteins greatly enhances the sensitivity of mammalian cells to DNA damage by ionizing radiation. We examined the possibility that the ease of dissociation of histones, or the association of other nuclear protein
Publikováno v:
Radiation Research. 136:130
The comet assay, a sensitive method of measuring DNA strand breaks in individual cells, is also capable of identifying apoptotic cells which contain highly fragmented DNA. This method requires embedding cells in agarose, lysing cells to remove protei
Publikováno v:
Radiation Research. 122:86