Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Judit Osz"'
Autor:
Carole Peluso-Iltis, Noé Pierrat, Daniela Rovito, Judit Osz, Daisuke Sawada, Atsushi Kittaka, Gilles Laverny, Natacha Rochel
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 551 (2024)
The active vitamin D metabolites, 25-hydroxyvitamin D3 (25D3) and 1,25-dihydroxyvitamin D3 (1,25D3), are produced by successive hydroxylation steps and play key roles in several cellular processes. However, alternative metabolic pathways exist, and a
Externí odkaz:
https://doaj.org/article/6f69e07507a2488cbea5e57ef69b5386
Autor:
Natacha Rochel, Clémentine Krucker, Laure Coutos-Thévenot, Judit Osz, Ruiyun Zhang, Elodie Guyon, Wayne Zita, Séverin Vanthong, Oscar Alba Hernandez, Maxime Bourguet, Kays Al Badawy, Florent Dufour, Carole Peluso-Iltis, Syrine Heckler-Beji, Annick Dejaegere, Aurélie Kamoun, Aurélien de Reyniès, Yann Neuzillet, Sandra Rebouissou, Claire Béraud, Hervé Lang, Thierry Massfelder, Yves Allory, Sarah Cianférani, Roland H. Stote, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of the PPARγ/RXRα pathway in luminal bladder cancers has mainly been linked to PPARG gene amplifications and activating point mutations in RXRα. Here, the authors identify recurrent PPARγ mutations with similar effects and elucidate th
Externí odkaz:
https://doaj.org/article/5e44a383003c4ce0b87b4a701664d7c3
Autor:
Olga Kolesnikova, Amélie Zachayus, Simon Pichard, Judit Osz, Natacha Rochel, Paola Rossolillo, Isabelle Kolb-Cheynel, Nathalie Troffer-Charlier, Emmanuel Compe, Olivier Bensaude, Imre Berger, Arnaud Poterszman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/e4e780ce6fc740d984f61a55ea5b32a1
Publikováno v:
PPAR Research, Vol 2012 (2012)
PPARγ is a key regulator of glucose homeostasis and insulin sensitization. PPARγ must heterodimerize with its dimeric partner, the retinoid X receptor (RXR), to bind DNA and associated coactivators such as p160 family members or PGC-1α to regulate
Externí odkaz:
https://doaj.org/article/37fafe4c9c85467caf1a2db477b8300a
Autor:
Yoshiteru Sato, Nick Ramalanjaona, Tiphaine Huet, Noelle Potier, Judit Osz, Pierre Antony, Carole Peluso-Iltis, Pierre Poussin-Courmontagne, Eric Ennifar, Yves Mély, Annick Dejaegere, Dino Moras, Natacha Rochel
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15119 (2010)
Retinoic acid receptors (RARs) and Retinoid X nuclear receptors (RXRs) are ligand-dependent transcriptional modulators that execute their biological action through the generation of functional heterodimers. RXR acts as an obligate dimer partner in ma
Externí odkaz:
https://doaj.org/article/d2a19c9db72a4ebea9b6ac69ed9cb650
Publikováno v:
Organic Chemistry Frontiers. 9:1522-1530
Synthesis of six novel Gemini cholesterol analogues and the binding mode of one of them to RORγ.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb19fb89a2770166deefb4d67f8fbf15
https://doi.org/10.1039/d2qo00040g
https://doi.org/10.1039/d2qo00040g
Autor:
Valentin Bauer, Yves Nominé, Natacha Rochel, Jozica Dolenc, Gergő Gógl, Vladimir Yu. Torbeev, Gilles Travé, Andre Mitschler, Boris Schmidtgall, Judit Osz, Alexandra Cousido-Siah, Camille Kostmann, Bruno Kieffer
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2021, 12 (3), pp.1080-1089. ⟨10.1039/d0sc04482b⟩
Chemical Science, 2021, 12 (3), pp.1080-1089. ⟨10.1039/D0SC04482B⟩
Chemical Science, 12 (3)
Chemical Science, The Royal Society of Chemistry, 2021, 12 (3), pp.1080-1089. ⟨10.1039/d0sc04482b⟩
Chemical Science, 2021, 12 (3), pp.1080-1089. ⟨10.1039/D0SC04482B⟩
Chemical Science, 12 (3)
Intrinsically disordered proteins (IDPs) constitute a large portion of “Dark Proteome” – difficult to characterize or yet to be discovered protein structures. Here we used conformationally constrained α-methylated amino acids to bias the confo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6d58921d1aed4d1ea9ab820be41c3d
https://doi.org/10.1039/d0sc04482b
https://doi.org/10.1039/d0sc04482b
Autor:
Rita Sigüeiro, Laurent Bianchetti, Carole Peluso-Iltis, Sandra Chalhoub, Annick Dejaegere, Judit Osz, Natacha Rochel
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2022, 65 (7), pp.5821-5829. ⟨10.1021/acs.jmedchem.2c00171⟩
Journal of Medicinal Chemistry, 2022, 65 (7), pp.5821-5829. ⟨10.1021/acs.jmedchem.2c00171⟩
International audience; 1α,25-dihydroxyvitamin D 3 (1,25D 3) regulates many physiological processes in vertebrates by binding to the Vitamin D Receptor (VDR). Phylogenetic analysis indicates that jawless fishes are the most basal vertebrates exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d5e64aec52bae5cd5fb39623195f9c
https://hal.science/hal-03745351/document
https://hal.science/hal-03745351/document
Akademický článek
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Autor:
Carole Peluso-Iltis, Pierre Poussin-Courmontagne, Judit Osz, Yassmine Chebaro, Bruno Kieffer, Natacha Rochel, Justine Wolf, Alastair G. McEwen
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2019, 481, pp.44-52. ⟨10.1016/j.mce.2018.11.008⟩
Molecular and Cellular Endocrinology, Elsevier, 2019, 481, pp.44-52. ⟨10.1016/j.mce.2018.11.008⟩
Retinoid X Receptors (RXRs) act as dimer partners for several nuclear receptors including itself, binding to genomic DNA response elements and regulating gene transcription with cell and gene specificity. As homodimers, RXRs bind direct repeats of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2484f424d45be247a552cfd8c36d8c14
https://doi.org/10.1016/j.mce.2018.11.008
https://doi.org/10.1016/j.mce.2018.11.008