Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Judit K. Makara"'
Autor:
Balázs B. Ujfalussy, Judit K. Makara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The formation of functional synaptic clusters (FSCs) and their impact on somatic membrane potential (sVm) in vivo are poorly understood. Here, the authors develop a computational approach to show that FSCs have to form via local rather than global pl
Externí odkaz:
https://doaj.org/article/26deb0c6b32c4646ba6e041777e4dbff
Autor:
Snezana Raus Balind, Ádám Magó, Mahboobeh Ahmadi, Noémi Kis, Zsófia Varga-Németh, Andrea Lőrincz, Judit K. Makara
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output funct
Externí odkaz:
https://doaj.org/article/ec5ccf2302a34094ab1326a2f2915776
Autor:
Jens P. Weber, Bertalan K. Andrásfalvy, Marina Polito, Ádám Magó, Balázs B. Ujfalussy, Judit K. Makara
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Inputs to functionally related synapses have been suggested to show cooperative summation, although the rules governing these interactions are unclear. Here, Weber et al. uncover non-linear interactions dependent on NMDAR signalling that vary across
Externí odkaz:
https://doaj.org/article/79634141d9ac4cb090ce5046b093bc28
Publikováno v:
eLife, Vol 10 (2021)
Proper integration of different inputs targeting the dendritic tree of CA3 pyramidal cells (CA3PCs) is critical for associative learning and recall. Dendritic Ca2+ spikes have been proposed to perform associative computations in other PC types by det
Externí odkaz:
https://doaj.org/article/a88b6144699e473590b1d782a233fae6
Publikováno v:
eLife, Vol 4 (2015)
Cortical neurons integrate thousands of synaptic inputs in their dendrites in highly nonlinear ways. It is unknown how these dendritic nonlinearities in individual cells contribute to computations at the level of neural circuits. Here, we show that d
Externí odkaz:
https://doaj.org/article/c370d72abfbe4504b7932637fac5562b
Proper integration of different inputs targeting the dendritic tree of CA3 pyramidal cells (CA3PCs) is critical for associative learning and recall. Dendritic Ca2+ spikes have been proposed to perform associative computations in other PC types, by de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449f7b83dfac1540367046572b206fad
https://doi.org/10.1101/2021.10.11.463888
https://doi.org/10.1101/2021.10.11.463888
Autor:
Judit K. Makara, Zsófia Varga-Németh, Ádám Magó, Andrea Lőrincz, Mahboobeh Ahmadi, Noémi Kis, Snezana Raus Balind
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Complex spike bursts (CSBs) represent a characteristic firing pattern of hippocampal pyramidal cells (PCs). In CA1PCs, CSBs are driven by regenerative dendritic plateau potentials, produced by correlated entorhinal cortical and CA3 inputs that simult
Publikováno v:
Neuron
Summary Dendrites integrate inputs nonlinearly, but it is unclear how these nonlinearities contribute to the overall input-output transformation of single neurons. We developed statistically principled methods using a hierarchical cascade of linear-n
Autor:
Jeffrey C. Magee, Judit K. Makara
Publikováno v:
Neuron
Summary The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arr