Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Judit García-Gonzalez"'
Autor:
Ester Antón-Galindo, Maja Adel, Judit García-Gonzalez, Adele Leggieri, Laura López-Blanch, Manuel Irimia, William HJ Norton, Caroline H Brennan, Noèlia Fernàndez-Castillo, Bru Cormand
Publikováno v:
bioRxiv
RBFOX1is a highly pleiotropic gene that contributes to several psychiatric and neurodevelopmental disorders. Both rare and common variants inRBFOX1have been associated with several psychiatric conditions, but the mechanisms underlying the pleiotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731d8971638c757d41e8c2f0d04a8db2
https://doi.org/10.1101/2023.02.23.529711
https://doi.org/10.1101/2023.02.23.529711
Autor:
Ester Antón-Galindo, Maja R. Adel, Judit García-González, Adele Leggieri, Laura López-Blanch, Manuel Irimia, William H. J. Norton, Caroline H. Brennan, Noèlia Fernàndez-Castillo, Bru Cormand
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract RBFOX1 is a highly pleiotropic gene that contributes to several psychiatric and neurodevelopmental disorders. Both rare and common variants in RBFOX1 have been associated with several psychiatric conditions, but the mechanisms underlying the
Externí odkaz:
https://doaj.org/article/8aa026a5ba2f435b917e2d9d09838519
Publikováno v:
GigaByte (2023)
Recent advances in genome-wide association and sequencing studies have shown that the genetic architecture of complex traits and diseases involves a combination of rare and common genetic variants distributed throughout the genome. One way to better
Externí odkaz:
https://doaj.org/article/95d741d8040945f6994d4e735fc0da12
Autor:
Shing Wan Choi, Judit García-González, Yunfeng Ruan, Hei Man Wu, Christian Porras, Jessica Johnson, Bipolar Disorder Working group of the Psychiatric Genomics Consortium, Clive J Hoggart, Paul F O'Reilly
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010624 (2023)
Polygenic risk scores (PRSs) have been among the leading advances in biomedicine in recent years. As a proxy of genetic liability, PRSs are utilised across multiple fields and applications. While numerous statistical and machine learning methods have
Externí odkaz:
https://doaj.org/article/fa6cb295ad9744b995c23552d54898cf
Autor:
Jose V. Torres-Pérez, Sofia Anagianni, Aleksandra M. Mech, William Havelange, Judit García-González, Scott E. Fraser, Giorgio Vallortigara, Caroline H. Brennan
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105704- (2023)
Summary: BAZ1B is a ubiquitously expressed nuclear protein with roles in chromatin remodeling, DNA replication and repair, and transcription. Reduced BAZ1B expression disrupts neuronal and neural crest development. Variation in the activity of BAZ1B
Externí odkaz:
https://doaj.org/article/a506e2d7cf1d4d6c9c65762018cca7e3
Autor:
Adele Leggieri, Judit García-González, Jose V. Torres-Perez, William Havelange, Saeedeh Hosseinian, Aleksandra M. Mech, Marcus Keatinge, Elisabeth M. Busch-Nentwich, Caroline H. Brennan
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Ankyrin repeat and kinase domain containing 1 (ANKK1) is a member of the receptor-interacting protein serine/threonine kinase family, known to be involved in cell proliferation, differentiation and activation of transcription factors. Genetic variati
Externí odkaz:
https://doaj.org/article/d30b7eef273e45cb91265d3e056fc9c7
Autor:
Judit García-González, Alistair J Brock, Matthew O Parker, Riva J Riley, David Joliffe, Ari Sudwarts, Muy-Teck Teh, Elisabeth M Busch-Nentwich, Derek L Stemple, Adrian R Martineau, Jaakko Kaprio, Teemu Palviainen, Valerie Kuan, Robert T Walton, Caroline H Brennan
Publikováno v:
eLife, Vol 9 (2020)
To facilitate smoking genetics research we determined whether a screen of mutagenized zebrafish for nicotine preference could predict loci affecting smoking behaviour. From 30 screened F3 sibling groups, where each was derived from an individual ethy
Externí odkaz:
https://doaj.org/article/5047a4e5ac344a06a8f71324faeda877
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225763 (2019)
There is extensive evidence of gender inequality in research leading to insufficient representation of women in leadership positions. Numbers revealing a gender gap in research are periodically reported by national and international institutions but
Externí odkaz:
https://doaj.org/article/a40dcd7b2e9b49fdba947551299da2ce
Autor:
Judit García-González, Bruno de Quadros, William Havelange, Alistair J. Brock, Caroline H. Brennan
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 319 (2021)
Synthetic cannabinoids can cause acute adverse psychological effects, but the potential impact when exposure happens before birth is unknown. Use of synthetic cannabinoids during pregnancy may affect fetal brain development, and such effects could be
Externí odkaz:
https://doaj.org/article/fe8b7a75d6044c82a22163c9ebe5027c
Autor:
Cristina Aguado, Magdalena Gayà-Vidal, Sergi Villatoro, Meritxell Oliva, David Izquierdo, Carla Giner-Delgado, Víctor Montalvo, Judit García-González, Alexander Martínez-Fundichely, Laia Capilla, Aurora Ruiz-Herrera, Xavier Estivill, Marta Puig, Mario Cáceres
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004208 (2014)
In recent years different types of structural variants (SVs) have been discovered in the human genome and their functional impact has become increasingly clear. Inversions, however, are poorly characterized and more difficult to study, especially tho
Externí odkaz:
https://doaj.org/article/c063a70f211f473097dde4cbc2d26590