Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Judit DomÈnech, Omella"'
Autor:
Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A. Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P. Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Tumour suppressors are inhibited in cancers and their reactivation could provide novel therapy opportunities. Here, the authors study the structural mechanism by which human tumour suppressor Protein Phosphatase 2A is inhibited in breast cancer cells
Externí odkaz:
https://doaj.org/article/a40d0289287e4365ac202e20daf82ec2
Autor:
Bob Meeusen, Emanuela Elsa Cortesi, Veerle Janssens, Juan-Jose Ventura, Anna Sablina, Judit Domènech Omella
Publikováno v:
Cancer letters. 520
KRAS-mutant lung adenocarcinomas represent the largest molecular subgroup of non-small cell lung cancers (NSCLC) and are notorious for their dismal survival perspectives. To gain more insights in etiology and therapeutic response, we focused on the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332d249886569b78fd6640c0e5af813f
https://pubmed.ncbi.nlm.nih.gov/34216687
https://pubmed.ncbi.nlm.nih.gov/34216687
Autor:
Judit Domènech Omella, Lut Overbergh, Chantal Mathieu, Louis Libbrecht, Etienne Waelkens, Veerle Janssens, Gabriela B Ferreira, Rita Vos, Caroline Lambrecht, Rita Derua
BACKGROUND: Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Mice lacking the tumor-suppressive protein phosphatase 2A subunit B56δ (Ppp2r5d) spontaneously develop HCC, correlating with increased c-MYC oncogenicity. MATERIAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58cd3b5252c0dc50bded017586d4e12
https://lirias.kuleuven.be/handle/123456789/662107
https://lirias.kuleuven.be/handle/123456789/662107
Autor:
Caroline, Lambrecht, Gabriela Bomfim, Ferreira, Judit DomÈnech, Omella, Louis, Libbrecht, Rita, DE Vos, Rita, Derua, Chantal, Mathieu, Lut, Overbergh, Etienne, Waelkens, Veerle, Janssens
Publikováno v:
Cancer Genomics Proteomics
Background: Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Mice lacking the tumor-suppressive protein phosphatase 2A subunit B56δ (Ppp2r5d) spontaneously develop HCC, correlating with increased c-MYC oncogenicity. Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e55e76a3ecba4b0c02f913f51b2d7029
https://pubmed.ncbi.nlm.nih.gov/33099469
https://pubmed.ncbi.nlm.nih.gov/33099469
Autor:
Erik Renström, Jiangming Sun, Yang De Marinis, Judit Domènech Omella, Amitabh Sharma, Martin Ridderstråle, Pradeep Bompada, Arda Halu, Cheng Luan
Publikováno v:
Obesity. 25:1400-1409
Objective Nuclear receptor interacting protein 1 (NRIP1) is an important energy regulator, but few studies have addressed its role in humans. This study investigated adipose tissue and skeletal muscle NRIP1 gene expression and serum levels in respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959924db1a8bb38fb7e4784adcf83517
https://doi.org/10.1002/oby.21899
https://doi.org/10.1002/oby.21899
Autor:
Anna Bordas, Veerle Janssens, Cristóbal de los Ríos, Carmen Montiel, José Luis Cedillo, Judit Domènech Omella, Raquel L Arribas
Publikováno v:
Bioorganic Chemistry. 100:103874
We herein report the design, synthesis, and functional impact of an okadaic acid (OA) small analogue, ITH12680, which restores the activity of phosphoprotein phosphatase 2A (PP2A), whose deficient activity has been implicated in nicotine-mediated tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3abf54de7fb4572cfe0717a9fadb51
https://doi.org/10.1016/j.bioorg.2020.103874
https://doi.org/10.1016/j.bioorg.2020.103874
Autor:
Yang De Marinis, Leif Groop, Jason Wright, Pradeep Bompada, Judit Domènech Omella, Cheng Luan, Emilia Ottosson Laakso, David Atac, Robin Andersson
Thioredoxin-interacting protein (TXNIP) has been shown to be associated with glucose-induced deterioration of pancreatic beta cell function in diabetes. However, whether epigenetic mechanisms contribute to the regulation of TXNIP gene expression by g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072cea64c283372d579e5322fda1113b
http://hdl.handle.net/10138/231342
http://hdl.handle.net/10138/231342