Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Judit Cervenak"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76839 (2013)
Immune suppression with rabbit anti-thymocyte globulin (rATG) is a well-established therapeutic concept for preventing host rejection of transplanted organs and graft versus host disease. Increasing the efficiency of rATG production by reducing the n
Externí odkaz:
https://doaj.org/article/491fd990c89341aa9c8b82cf3454a8cd
Autor:
Attila Végh, Anita Farkas, Dorottya Kövesdi, Krisztián Papp, Judit Cervenak, Zita Schneider, Balázs Bender, László Hiripi, Glória László, József Prechl, János Matkó, Imre Kacskovics
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36286 (2012)
Our previous studies have shown that overexpression of bovine FcRn (bFcRn) in transgenic (Tg) mice leads to an increase in the humoral immune response, characterized by larger numbers of Ag-specific B cells and other immune cells in secondary lymphoi
Externí odkaz:
https://doaj.org/article/e73db012f6ba46269373f914c97ac212
Autor:
Ana Paula Catunda Lemos, Judit Cervenak, Balázs Bender, Orsolya Ivett Hoffmann, Mária Baranyi, Andrea Kerekes, Anita Farkas, Zsuzsanna Bosze, László Hiripi, Imre Kacskovics
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28869 (2012)
The neonatal Fc receptor (FcRn) regulates IgG and albumin homeostasis, mediates maternal IgG transport, takes an active role in phagocytosis, and delivers antigen for presentation. We have previously shown that overexpression of FcRn in transgenic mi
Externí odkaz:
https://doaj.org/article/a2265c3922bb431d9cb35383c0c5b780
Publikováno v:
Immunological Reviews. 268:269-287
In recent years, there has been an increasing demand for the development of faster and more efficient technologies for the generation of monoclonal antibodies against challenging targets that are weakly immunogenic or available only in limited amount
Autor:
Judit Cervenak, Balázs Mayer, Zita Schneider, Márton Doleschall, Lennart Hammarström, Wolfgang Oster, Yaofeng Zhao, Imre Kacskovics, Balázs Bender, Zoltán Doleschall, Zsuzsanna Bősze
Publikováno v:
mAbs. 5:860-871
Among the many functions of the neonatal Fc receptor (FcRn) for IgG, it binds to IgG-opsonized antigen complexes and propagates their traffic into lysosomes where antigen processing occurs. We previously reported that transgenic (Tg) mice and rabbits
Autor:
József Prechl, Zita Schneider, Judit Cervenak, Mária Baranyi, Anna Erdei, Imre Kacskovics, Krisztián Papp, Glória László
Publikováno v:
Immunology Letters. 137:62-69
The overexpression of the bovine neonatal Fc receptor (bFcRn) in transgenic (Tg) mice boosts humoral immune response with increased numbers of antigen-specific spleen cells and a potent humoral immune response against weakly immunogenic targets. One
Publikováno v:
Developmental & Comparative Immunology. 31:945-961
The full length coding sequence of the cattle transcription factor p65 was isolated and cloned. The cloned bovine p65 was expressed in mammalian cells, and it induced the NF-kappaB-specific luciferase reporter gene expression. Using gel retardation t
Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling
Autor:
Marco Pistis, Sang-Hun Lee, Miriam Melis, Csaba Varga, Rita Nyilas, Claudia Sagheddu, Barna Dudok, Marco Ledri, Ivan Soltesz, Szilárd I. Szabó, Stephen G. Woodhams, Judit Cervenak, Christopher M. Henstridge, Eszter Szabadits, István Katona, Masahiko Watanabe, Balazs Pinter, Gyula Y. Balla, László Barna, Imre Kacskovics, Máté Matolcsi
Publikováno v:
Nature neuroscience
A major challenge in neuroscience is to determine the nanoscale position and quantity of signaling molecules in a cell type- and subcellular compartment-specific manner. We developed a new approach to this problem by combining cell-specific physiolog
Autor:
Katalin Német, Gerrit Jan Koomen, Csilla Özvegy-Laczka, Gabriella Köblös, Olga Ujhelly, György Várady, Judit Cervenak, Brian P. Sorrentino, Balázs Sarkadi, John D. Schuetz, András Váradi
Publikováno v:
The Journal of Biological Chemistry, 280(6), 4219-4227. American Society for Biochemistry and Molecular Biology Inc.
The human ABCG2 protein is an important primary active transporter for hydrophobic compounds in several cell types, and its overexpression causes multidrug resistance in tumors. A monoclonal antibody (5D3) recognizes this protein on the cell surface.
Autor:
Balázs Sarkadi, Judit Cervenak, Olga Ujhelly, Manuel Grez, Dirk Roos, László Homolya, George L. Scheffer, András Váradi, György Várady, Susan E. Bates, Csilla Özvegy, Katalin Német
Publikováno v:
Human gene therapy, 14(4), 403-412. Mary Ann Liebert Inc.
OVERVIEW SUMMARY Stem cell-based gene therapy is often unsuccessful because of the relatively low number of genetically modified cells with repopulating capabilities. To provide a selective advantage for the modified cells we applied the human ABCG2