Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Judit Castillo-Armengol"'
Autor:
Sylviane Lagarrigue, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Veronica Jimenez, Carine Chavey, Albert Giralt, Qiuwen Lai, Lianjun Zhang, Laia Martinez-Carreres, Brigitte Delacuisine, Jean-Sébastien Annicotte, Emilie Blanchet, Sébastien Huré, Anna Abella, Francisco J. Tinahones, Joan Vendrell, Pierre Dubus, Fatima Bosch, C. Ronald Kahn, Lluis Fajas
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/1453ec066ed340c8a243912c98d2ac0f
Autor:
Alexandre Picard, Xavier Berney, Judit Castillo-Armengol, David Tarussio, Maxime Jan, Ana Rodriguez Sanchez-Archidona, Sophie Croizier, Bernard Thorens
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101479- (2022)
Objectives: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomou
Externí odkaz:
https://doaj.org/article/2ad4c210c7f44faa88e5c07a91e1f5dc
Autor:
Sylviane Lagarrigue, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Veronica Jimenez, Carine Chavey, Albert Giralt, Qiuwen Lai, Lianjun Zhang, Laia Martinez-Carreres, Brigitte Delacuisine, Jean-Sébastien Annicotte, Emilie Blanchet, Sébastien Huré, Anna Abella, Francisco J. Tinahones, Joan Vendrell, Pierre Dubus, Fatima Bosch, C. Ronald Kahn, Lluis Fajas
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Externí odkaz:
https://doaj.org/article/4642ee6f471f48639eb3b9f1fb308211
Autor:
Honglei Ji, Yizhe Chen, Judit Castillo-Armengol, René Dreos, Catherine Moret, Guy Niederhäuser, Brigitte Delacuisine, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Lluis Fajas
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101163- (2020)
Summary: Cyclin-dependent kinases (CDKs) are emerging regulators of adipose tissue metabolism. Here we aimed to explore the role of CDK7 in thermogenic fat. We found that CDK7 brown adipose tissue (BAT)-specific knockout mice (Cdk7bKO) have decreased
Externí odkaz:
https://doaj.org/article/1684df4debab4ace9a78378cb737c5c4
Autor:
Lluis Fajas, Isabel C. Lopez-Mejia, Pedro Romero, Lianjun Zhang, Angélique Pabois, Anita Nasrallah, Valentin Barquissau, Catherine Moret, Oleksandr Dergai, Albert Giralt, Judit Castillo-Armengol, Meritxell Orpinell, Lucía C. Leal-Esteban, Julien Puyal, Laia Martínez-Carreres
Supplementary Figures and Supplementary Figure legends. Supplementary Fig. 1.- CDK4 inhibition or depletion decreases mTORC1 activity in several cancer cell lines, Supplementary Fig. 2.- CDK4 effects on mTORC1 are α-ketoglutarate and E2F1-independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab448ab8dcf5d7f5550bd63893fa293
https://doi.org/10.1158/0008-5472.22422338.v1
https://doi.org/10.1158/0008-5472.22422338.v1
Autor:
Lluis Fajas, Isabel C. Lopez-Mejia, Pedro Romero, Lianjun Zhang, Angélique Pabois, Anita Nasrallah, Valentin Barquissau, Catherine Moret, Oleksandr Dergai, Albert Giralt, Judit Castillo-Armengol, Meritxell Orpinell, Lucía C. Leal-Esteban, Julien Puyal, Laia Martínez-Carreres
Cyclin-dependent kinase 4 (CDK4) is well-known for its role in regulating the cell cycle, however, its role in cancer metabolism, especially mTOR signaling, is undefined. In this study, we established a connection between CDK4 and lysosomes, an emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c42bc5713c371dfadfd076bd4869d2
https://doi.org/10.1158/0008-5472.c.6511187.v1
https://doi.org/10.1158/0008-5472.c.6511187.v1
Autor:
Lluis Fajas, Isabel C. Lopez-Mejia, Pedro Romero, Lianjun Zhang, Angélique Pabois, Anita Nasrallah, Valentin Barquissau, Catherine Moret, Oleksandr Dergai, Albert Giralt, Judit Castillo-Armengol, Meritxell Orpinell, Lucía C. Leal-Esteban, Julien Puyal, Laia Martínez-Carreres
Supplementary Tables. Supplementary Table 1. Target sequences for guide RNA used to create KO stable cell lines with CRISP/Cas9 technology, Supplementary Table 2. Primers used for qPCR Analysis of Transcription Factor EB (TFEB) regulated genes (human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3ca4568c0e323d04ed13310ca03531
https://doi.org/10.1158/0008-5472.22422335
https://doi.org/10.1158/0008-5472.22422335
Autor:
Lluis Fajas, Isabel C. Lopez-Mejia, Pedro Romero, Lianjun Zhang, Angélique Pabois, Anita Nasrallah, Valentin Barquissau, Catherine Moret, Oleksandr Dergai, Albert Giralt, Judit Castillo-Armengol, Meritxell Orpinell, Lucía C. Leal-Esteban, Julien Puyal, Laia Martínez-Carreres
Supplementary Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e49fd7697b08c25aa0cf84e4d26a2a0
https://doi.org/10.1158/0008-5472.22422341.v1
https://doi.org/10.1158/0008-5472.22422341.v1
Autor:
Valentin Barquissau, Nadège Zanou, Sarah Geller, Judit Castillo-Armengol, Flavia Marzetta, Katharina Huber, Dorian Ziegler, Isabel Lopez-Mejia, Joan Blanco Fernandez, Catherine Roger, Nicolas Guex, Frédéric Preitner, Jean-Marc Vanacker, Lluis Fajas
Cyclin-dependent kinase 4 (CDK4) canonical role is to control cell cycle progression from G1 to S phases. However, recent studies reported that CDK4 regulates energy metabolism in non-proliferating cells such as hepatocytes or adipocytes. The objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94639281f009758fc162a0fc7c028729
https://doi.org/10.1101/2022.03.03.482783
https://doi.org/10.1101/2022.03.03.482783
Autor:
Julien Puyal, Judit Castillo-Armengol, Albert Giralt, Oleksandr Dergai, Lluis Fajas, Anita Nasrallah, Catherine Moret, Valentin Barquissau, Lucia C Leal-Esteban, Angélique Pabois, Isabel C. Lopez-Mejia, Laia Martinez-Carreres, Lianjun Zhang, Meritxell Orpinell, Pedro Romero
Publikováno v:
Cancer Res
Cyclin-dependent kinase 4 (CDK4) is well-known for its role in regulating the cell cycle, however, its role in cancer metabolism, especially mTOR signaling, is undefined. In this study, we established a connection between CDK4 and lysosomes, an emerg