Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3'-untranslated regions

Autor: Judit Asenjo, Manuela Moraru, Karima Al‐Akioui‐Sanz, Mireia Altadill, Aura Muntasell, Miguel López‐Botet, Carlos Vilches

Data de publicació electrònica: 08-07-2022 NK cells monitor altered molecular patterns in tumors and infected cells through an ample array of receptors. Two families of evolutionarily distant receptors have converged to enable human NK cells to sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83e86d1679fc7ed93aa832fc23b67c0
http://hdl.handle.net/10230/54008

Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

Autor: Chantal Reina-Ortiz, Diego Sánchez-Martínez, Carlos Vilches, Daniel Woods, Isabel Marzo, Tania Calvo, Gemma Azaceta, Joaquín Marco-Brualla, Luis Palomera, María Gascón, Martin Villalba, Isabel Izquierdo, Alberto Anel, David Giraldos, Javier Naval, Judit Asenjo

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19398. ⟨10.1038/s41598-020-76051-z⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Consejo Superior de Investigaciones Científicas (CSIC)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza

Adoptive transfer of allogeneic natural killer (NK) cells is becoming a credible immunotherapy for hematological malignancies. In the present work, using an optimized expansion/activation protocol of human NK cells, we generate expanded NK cells (eNK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6464e4fe425ae7025782fff7ec25b5ba
https://hal.umontpellier.fr/hal-03010044