Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema

Autor: David S. Boyer, 1 Young Hee Yoon, MD, PhD, 2 Rubens Belfort, Jr, MD, PhD, 3 Francesco Bandello, 4 Raj K. Maturi, 5 Albert J. Augustin, 6 Xiao Yan Li, 7 Harry Cui, 7 Yehia Hashad, 7 Scott M. Whitcup, MDThe MEAD Study Group Principal Investigators: Suel Abujamra, James Acton, Fareed Ali, Andrew Antoszyk, Albert J. Augustin, Carl C. Awh, Adiel Barak, Karl Ulrich Bartz Schmidt, Caroline R. Baumal, Rubens Belfort, J.r., Muna Bhende, William Z. Bridges, David M. Brown, Trevor Carmichael, Ken Carnevale, Antonio M. Casella, Tom Chang, Daniel Chechik, San Ni Chen, Lawrence P. Chong, Victor Chong, Joel Corwin, Catherine Creuzot Garcher, Alan Cruess, Mark Daniell, Marcos P. de Avila, Haroldo Vieira de Moraes, Robert G. Devenyi, Bernard H. Doft, Mark Donaldson, Richard Dreyer, Dean Eliott, Harry M. Engel, Jan Ernest, Thomas F. Essman, Philip M. Falcone, Sharon Fekrat, Joseph R. Ferencz, Joao L. Ferreira, Joao Figueira, Ivan Fiser, Bradley Foster, Gregory M. Fox, William R. Freeman, S. P. Garg, Mark Gillies, David Glaser, Burton G. Goldstein, Andre M. V. Gomes, John R. Gonder, Lingam Gopal, Petrus Gous, Amod Gupta, Anurag Gupta, Lawrence Halperin, Dennis Han, Seenu M. Hariprasad, Frank G. Holz, Peter Kaiser, Bohdana Kalvodova, Barrett Katz, Randy S. Katz, Dariusz Kecik, Judianne Kellaway, Itamar Klemperer, Baruch Kuppermann, Paolo Lanzetta, Rosangela Lattanzio, Won Ki Lee, John Lehr, Monique Leys, Isaac Loose, Andrew Lotery, Da Wen Lu, Paul McCartney, Ajit B. Majji, Jose A. Martinez, Pascale Massin, Raj K. Maturi, Ugo Menchini, Geeta Menon, Mark Michels, Edoardo Midena, James Miller, Paul Mitchell, Joseph Moisseiev, Lawrence Morse, Rafael Navarro, Janos Nemeth, Henry Newland, Richard Newsom, John Nichols, Juan Orellana, Nicola Orzalesi, Augusto Paranhos, Robert Park, Susanna Park, Maurizio Battaglia Parodi, Peter R. Pavan, James Peace, Don J. Perez Ortiz, Ayala Pollack, Kim Ramaswamy, Ramakrishna Ratnakaram, Giuseppe Ravalico, Jiri Rehak, Kourous Rezaei, Stanislao Rizzo, Francisco J. Rodriguez Alvira, Jean Paul Romanet, Steven Rose, Richard B. Rosen, Luca Rossetti, Jose Maria Ruiz Moreno, SriniVas Sadda, Kenneth Sall, Dirk Sandner, Alvaro Fernandez Vega Sanz, Gil Sartani, Stefanie Schmickler, Steven D. Schwartz, Y. R. Sharma, Shwu Jiuan Sheu, Michael Singer, Sobha Sivaprasad, Gisele Soubrane, Petr Soucek, Eric H. Souied, Giovanni Staurenghi, Jan Studnicka, Marta Suarez Figueroa, Walter Y. Takahashi, Patrick L. Tsai, Lawrence J. Ulanski, Harvey Uy, Monica Varano, Miroslav Veith, Igor Vicha, Francesco Viola, Linda Visser, Dov Weinberger, Glenn L. Wing, Edmund Wong, Tien Wong, Edward Wylegala, Jiong Yan, Young Hee Yoon, Lucy H. Young, Hyeong G. Yu, Ingrid E. Zimmer Galler, TOGNETTO, DANIELE

Publikováno v: Ozurdex MEAD Study Group & Newsom, R B 2014, ' Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema ', Ophthalmology, vol. 121, no. 10, pp. 1904-1914 . https://doi.org/10.1016/j.ophtha.2014.04.024

Purpose: To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex, DEX implant) 0.7 and 0.35 mg in the treatment of patients with diabetic macular edema (DME).Design: Two randomized, multicenter, masked, sham-controlled, pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6868a174f5dad2c622dd901451a00
https://doi.org/10.1016/j.ophtha.2014.04.024

West Nile Virus Retinopathy and Associations with Long Term Neurological and Neurocognitive Sequelae

Autor: Steven Paul Woods, Rodrigo Hasbun, Melissa N. Garcia, Lucrecia Salazar, Judianne Kellaway, Laura D. Baker, Kristy O. Murray

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0148898 (2016)

West Nile virus (WNV) has emerged as an important vector-borne pathogen in North America, with more than 3 million estimated to have been infected. Retinopathy from WNV infection has been previously reported in acute cases, though those prior reports

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefd5db5e953b776182efdaefa6d2b57
http://europepmc.org/articles/PMC4780769

Melanocytoma of the ciliary body diagnosed by fine-needle aspiration biopsy

Autor: Judianne Kellaway, Ramon L. Font, Sherif M. El-Harazi

Publikováno v: Diagnostic Cytopathology. 22:394-397

A 55-yr-old African American man was referred for evaluation of a mass involving the anterior choroid/ciliary body in his left eye. Dilated fundus examination revealed a large, deeply pigmented mass associated with an exudative retinal detachment. Ul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92a9accc9228ca391a5c90aedbd4f629
https://doi.org/10.1002/(sici)1097-0339(200006)22:6<394::aid-dc13>3.0.co

Evaluation of ocular safety

Autor: Richard G. Urso, Thomas C. Prager, Judianne Kellaway, Susan McIntyre, Agop Y. Bedikian, Yali Zou

Publikováno v: Anti-Cancer Drugs. 9:515-524

Ninety-six patients with metastatic melanoma treated with two consecutive tirapazamine-cisplatin combination chemotherapy regimens were followed for signs of therapy-related ocular toxicity. Baseline and follow-up data were obtained such that each pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de5b8d9411faf9f4eaba7a909aa47cb8
https://doi.org/10.1097/00001813-199807000-00001

Triple viral retinitis diagnosed by polymerase chain reaction of the vitreous biopsy in a patient with Richter syndrome

Autor: Mark T. Chiu, Chi-Chao Chan, Yun Wang, John J. Hooks, Ralph D. Levinson, Judianne Kellaway

Publikováno v: American journal of ophthalmology. 126(5)

PURPOSE: To report the evaluation and identification of herpes viruses associated with retinitis in a patient with Richter syndrome. METHODS: Diagnostic vitrectomy was performed on a patient with systemic leukemia and retinitis. The vitreous sample w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702388ce1f53f3c1f18887662749810a
https://pubmed.ncbi.nlm.nih.gov/9822244