Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Judes, Poirier"'
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 11, Pp 100667- (2024)
Apolipoprotein B (APOB), a receptor-binding protein present in cholesterol-rich lipoproteins, has been implicated in Alzheimer's disease (AD). High levels of APOB-containing low-density lipoproteins (LDL) are linked to the pathogenesis of both early-
Externí odkaz:
https://doaj.org/article/d5a51dd6eada4d4f80a2a1d7067b7aa5
Autor:
Alexandre Poirier, Cynthia Picard, Anne Labonté, Isabelle Aubry, Daniel Auld, Henrik Zetterberg, Kaj Blennow, the PREVENT-AD research group, Michel L. Tremblay, Judes Poirier
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract We examined the role of protein tyrosine phosphatase receptor sigma (PTPRS) in the context of Alzheimer’s disease and synaptic integrity. Publicly available datasets (BRAINEAC, ROSMAP, ADC1) and a cohort of asymptomatic but “at risk” i
Externí odkaz:
https://doaj.org/article/5c2bffc8281e4d86b7cc862b69f180cb
Autor:
Alfie Wearn, Stéfanie A. Tremblay, Christine L. Tardif, Ilana R. Leppert, Claudine J. Gauthier, Giulia Baracchini, Colleen Hughes, Patrick Hewan, Jennifer Tremblay-Mercier, Pedro Rosa-Neto, Judes Poirier, Sylvia Villeneuve, Taylor W. Schmitz, Gary R. Turner, R. Nathan Spreng, PREVENT-AD Research Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The neuromodulatory subcortical nuclei within the isodendritic core (IdC) are the earliest sites of tauopathy in Alzheimer’s disease (AD). They project broadly throughout the brain’s white matter. We investigated the relationship between
Externí odkaz:
https://doaj.org/article/d8062ce17ab54c72b84934986e6ff3ee
Autor:
Jason da Silva Castanheira, Alex I. Wiesman, Justine Y. Hansen, Bratislav Misic, Sylvain Baillet, John Breitner, Judes Poirier, Pierre Bellec, Véronique Bohbot, Mallar Chakravarty, Louis Collins, Pierre Etienne, Alan Evans, Serge Gauthier, Rick Hoge, Yasser Ituria-Medina, Gerhard Multhaup, Lisa-Marie Münter, Natasha Rajah, Pedro Rosa-Neto, Jean-Paul Soucy, Etienne Vachon-Presseau, Sylvia Villeneuve, Philippe Amouyel, Melissa Appleby, Nicholas Ashton, Daniel Auld, Gülebru Ayranci, Christophe Bedetti, Marie-Lise Beland, Kaj Blennow, Ann Brinkmalm Westman, Claudio Cuello, Mahsa Dadar, Leslie-Ann Daoust, Samir Das, Marina Dauar-Tedeschi, Louis De Beaumont, Doris Dea, Maxime Descoteaux, Marianne Dufour, Sarah Farzin, Fabiola Ferdinand, Vladimir Fonov, Julie Gonneaud, Justin Kat, Christina Kazazian, Anne Labonté, Marie-Elyse Lafaille-Magnan, Marc Lalancette, Jean-Charles Lambert, Jeannie-Marie Leoutsakos, Laura Mahar, Axel Mathieu, Melissa McSweeney, Pierre-François Meyer, Justin Miron, Jamie Near, Holly NewboldFox, Nathalie Nilsson, Pierre Orban, Cynthia Picard, Alexa Pichet Binette, Jean-Baptiste Poline, Sheida Rabipour, Alyssa Salaciak, Matthew Settimi, Sivaniya Subramaniapillai, Angela Tam, Christine Tardif, Louise Théroux, Jennifer Tremblay-Mercier, Stephanie Tullo, Irem Ulku, Isabelle Vallée, Henrik Zetterberg, Vasavan Nair, Jens Pruessner, Paul Aisen, Elena Anthal, Alan Barkun, Thomas Beaudry, Fatiha Benbouhoud, Jason Brandt, Leopoldina Carmo, Charles Edouard Carrier, Laksanun Cheewakriengkrai, Blandine Courcot, Doris Couture, Suzanne Craft, Christian Dansereau, Clément Debacker, René Desautels, Sylvie Dubuc, Guerda Duclair, Mark Eisenberg, Rana El-Khoury, Anne-Marie Faubert, David Fontaine, Josée Frappier, Joanne Frenette, Guylaine Gagné, Valérie Gervais, Renuka Giles, Renee Gordon, Clifford Jack, Benoit Jutras, Zaven Khachaturian, David Knopman, Penelope Kostopoulos, Félix Lapalme, Tanya Lee, Claude Lepage, Illana Leppert, Cécile Madjar, David Maillet, Jean-Robert Maltais, Sulantha Mathotaarachchi, Ginette Mayrand, Diane Michaud, Thomas Montine, John Morris, Véronique Pagé, Tharick Pascoal, Sandra Peillieux, Mirela Petkova, Galina Pogossova, Pierre Rioux, Mark Sager, Eunice Farah Saint-Fort, Mélissa Savard, Reisa Sperling, Shirin Tabrizi, Pierre Tariot, Eduard Teigner, Ronald Thomas, Paule-Joanne Toussaint, Miranda Tuwaig, Vinod Venugopalan, Sander Verfaillie, Jacob Vogel, Karen Wan, Seqian Wang, Elsa Yu, Isabelle Beaulieu-Boire, Pierre Blanchet, Sarah Bogard, Manon Bouchard, Sylvain Chouinard, Francesca Cicchetti, Martin Cloutier, Alain Dagher, Clotilde Degroot, Alex Desautels, Marie Hélène Dion, Janelle Drouin-Ouellet, Anne-Marie Dufresne, Nicolas Dupré, Antoine Duquette, Thomas Durcan, Lesley K. Fellows, Edward Fon, Jean-François Gagnon, Ziv Gan-Or, Angela Genge, Nicolas Jodoin, Jason Karamchandani, Anne-Louise Lafontaine, Mélanie Langlois, Etienne Leveille, Martin Lévesque, Calvin Melmed, Oury Monchi, Jacques Montplaisir, Michel Panisset, Martin Parent, Minh-Thy Pham-An, Ronald Postuma, Emmanuelle Pourcher, Trisha Rao, Jean Rivest, Guy Rouleau, Madeleine Sharp, Valérie Soland, Michael Sidel, Sonia Lai Wing Sun, Alexander Thiel, Paolo Vitali
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105201- (2024)
Summary: Background: Research in healthy young adults shows that characteristic patterns of brain activity define individual “brain-fingerprints” that are unique to each person. However, variability in these brain-fingerprints increases in indivi
Externí odkaz:
https://doaj.org/article/53cebec840074e92a908d46662561dae
Autor:
Andrée‐Ann Baril, Cynthia Picard, Anne Labonté, Erlan Sanchez, Catherine Duclos, Béry Mohammediyan, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, John C. S. Breitner, Sylvia Villeneuve, Judes Poirier, PREVENT‐AD Research Group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION Measuring day‐to‐day sleep variability might reveal unstable sleep‐wake cycles reflecting neurodegenerative processes. We evaluated the association between Alzheimer's disease (AD) fluid biomarkers with day‐to‐day slee
Externí odkaz:
https://doaj.org/article/f65f59e65abd48bbb9ebefd6cae1b6d9
Autor:
Kimia Shafighi, Sylvia Villeneuve, Pedro Rosa Neto, AmanPreet Badhwar, Judes Poirier, Vaibhav Sharma, Yasser Iturria Medina, Patricia P Silveira, Laurette Dube, David Glahn, Danilo Bzdok
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280471 (2023)
Alzheimer's disease and related dementias is a major public health burden-compounding over upcoming years due to longevity. Recently, clinical evidence hinted at the experience of social isolation in expediting dementia onset. In 502,506 UK Biobank p
Externí odkaz:
https://doaj.org/article/1f92ecf8631e4e6fbd563d9e093ed3f3
Autor:
Chloé Savignac, Sylvia Villeneuve, AmanPreet Badhwar, Karin Saltoun, Kimia Shafighi, Chris Zajner, Vaibhav Sharma, Sarah A Gagliano Taliun, Sali Farhan, Judes Poirier, Danilo Bzdok
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001863 (2022)
Alzheimer's disease is marked by intracellular tau aggregates in the medial temporal lobe (MTL) and extracellular amyloid aggregates in the default network (DN). Here, we examined codependent structural variations between the MTL's most vulnerable st
Externí odkaz:
https://doaj.org/article/74ba1e2d30774caab9e6c9616d67e47f
Autor:
Julie Gonneaud, Alex T. Baria, Alexa Pichet Binette, Brian A. Gordon, Jasmeer P. Chhatwal, Carlos Cruchaga, Mathias Jucker, Johannes Levin, Stephen Salloway, Martin Farlow, Serge Gauthier, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, John C. S. Breitner, Judes Poirier, Etienne Vachon-Presseau, Sylvia Villeneuve, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dominantly Inherited Alzheimer Network (DIAN) Study Group, Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Alzheimer’s disease has been associated with increased structural brain aging. Here the authors describe a model that predicts brain aging from resting state functional connectivity data, and demonstrate this is accelerated in individuals with pre-
Externí odkaz:
https://doaj.org/article/0c59d82b7ea64e8e9da8283d5d2f0d76
Autor:
Marina Tedeschi Dauar, Tharick Ali Pascoal, Joseph Therriault, Jared Rowley, Sara Mohaddes, Monica Shin, Eduardo R. Zimmer, Simon Fristed Eskildsen, Vladimir S. Fonov, Serge Gauthier, Judes Poirier, Pedro Rosa-Neto
Publikováno v:
Brain Sciences, Vol 13, Iss 2, p 232 (2023)
Associations between pathophysiological events and cognitive measures provide insights regarding brain networks affected during the clinical progression of Alzheimer’s disease (AD). In this study, we assessed patients’ scores in two delayed episo
Externí odkaz:
https://doaj.org/article/f904d0a3375446dcb225b3fc1ff58591
Autor:
Pierre‐François Meyer, Anne Labonté, Pedro Rosa‐Neto, Judes Poirier, John C. S. Breitner, the PREVENT‐AD Research Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 6, Pp 1127-1133 (2019)
Abstract We studied 78 participants having a parental or multiple‐sibling history of Alzheimer’s disease (AD) in a two‐year randomized placebo‐controlled trial of naproxen 220 mg b.i.d. for mitigation of early AD pathogenesis. Naproxen was de
Externí odkaz:
https://doaj.org/article/5c3e9170f6b24f3e87c3035f9716f23b