Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jude S. Bimela"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Accurate identification of beneficial mutations is central to antibody design. Many knowledge-based (KB) computational approaches have been developed to predict beneficial mutations, but their accuracy leaves room for improvement. Thermodynamic integ
Externí odkaz:
https://doaj.org/article/d3f240500ec24e6787024988a601c85c
Autor:
Jude S. Bimela, Aubin J. Nanfack, Pengpeng Yang, Shaoxing Dai, Xiang-Peng Kong, Judith N. Torimiro, Ralf Duerr
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Combinational antiretroviral therapy (cART) is the most effective tool to prevent and control HIV-1 infection without an effective vaccine. However, HIV-1 drug resistance mutations (DRMs) and naturally occurring polymorphisms (NOPs) can abrogate cART
Externí odkaz:
https://doaj.org/article/e1f621aaebd64dc9943603de438a7a33
Autor:
Zizhang Sheng, Jude S. Bimela, Phinikoula S. Katsamba, Saurabh D. Patel, Yicheng Guo, Haiqing Zhao, Youzhong Guo, Peter D. Kwong, Lawrence Shapiro
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Accumulation of somatic hypermutation (SHM) is the primary mechanism to enhance the binding affinity of antibodies to antigens in vivo. However, the structural basis of the effects of many SHMs remains elusive. Here, we integrated atomistic molecular
Externí odkaz:
https://doaj.org/article/5b26e403dfb447348f67dcb9f79d668a
Autor:
Micah Rapp, Yicheng Guo, Eswar R. Reddem, Jian Yu, Lihong Liu, Pengfei Wang, Gabriele Cerutti, Phinikoula Katsamba, Jude S. Bimela, Fabiana A. Bahna, Seetha M. Mannepalli, Baoshan Zhang, Peter D. Kwong, Yaoxing Huang, David D. Ho, Lawrence Shapiro, Zizhang Sheng
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108950- (2021)
Summary: Antibodies with heavy chains that derive from the VH1-2 gene constitute some of the most potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibodies yet identified. To provide insight into whether these geneti
Externí odkaz:
https://doaj.org/article/3a5457a2eb02476c94c3b855ab19a749
Autor:
Michael Tuen, Jude S. Bimela, Andrew N. Banin, Shilei Ding, Gordon W. Harkins, Svenja Weiss, Vincenza Itri, Allison R. Durham, Stephen F. Porcella, Sonal Soni, Luzia Mayr, Josephine Meli, Judith N. Torimiro, Marcel Tongo, Xiaohong Wang, Xiang-Peng Kong, Arthur Nádas, Daniel E. Kaufmann, Zabrina L. Brumme, Aubin J. Nanfack, Thomas C. Quinn, Susan Zolla-Pazner, Andrew D. Redd, Andrés Finzi, Miroslaw K. Gorny, Phillipe N. Nyambi, Ralf Duerr
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Genetic and immunologic analyses of epidemiologically-linked HIV transmission enable insights into the impact of immune responses on clinical outcomes. Human vaccine trials and animal studies of HIV-1 infection have suggested immune correlates of pro
Externí odkaz:
https://doaj.org/article/946a42bd643d416f901efe3b06b7ef4c
Autor:
Andrew N. Banin, Michael Tuen, Jude S. Bimela, Marcel Tongo, Paul Zappile, Alireza Khodadadi-Jamayran, Aubin J. Nanfack, Josephine Meli, Xiaohong Wang, Dora Mbanya, Jeanne Ngogang, Adriana Heguy, Phillipe N. Nyambi, Charles Fokunang, Ralf Duerr
Publikováno v:
Viruses, Vol 11, Iss 4, p 317 (2019)
Near full genome sequencing (NFGS) of HIV-1 is required to assess the genetic composition of HIV-1 strains comprehensively. Population-wide, it enables a determination of the heterogeneity of HIV-1 and the emergence of novel/recombinant strains, whil
Externí odkaz:
https://doaj.org/article/b904fd66c8774562957b278c6b65051c
Autor:
Zizhang Sheng, Jude S. Bimela, Phinikoula S. Katsamba, Saurabh D. Patel, Yicheng Guo, Haiqing Zhao, Youzhong Guo, Peter D. Kwong, Lawrence Shapiro
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2022)
Frontiers in Immunology, Vol 12 (2022)
Accumulation of somatic hypermutation (SHM) is the primary mechanism to enhance the binding affinity of antibodies to antigens in vivo. However, the structural basis of the effects of many SHMs remains elusive. Here, we integrated atomistic molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16e08a2c197e98f79bfe29abf887c7c
https://pubmed.ncbi.nlm.nih.gov/35046963
https://pubmed.ncbi.nlm.nih.gov/35046963
Autor:
Ralf Duerr, Phillipe N Nyambi, Miroslaw K Gorny, Andrés Finzi, Andrew D Redd, Susan Zolla-Pazner, Thomas C Quinn, Aubin J Nanfack, Zabrina L Brumme, Daniel E Kaufmann, Arthur Nádas, Xiang-Peng Kong, Xiaohong Wang, Marcel Tongo, Judith N Torimiro, Josephine Meli, Luzia Mayr, Sonal Soni, Stephen F Porcella, Allison R Durham, Vincenza Itri, Svenja Weiss, Gordon W Harkins, Shilei Ding, Andrew N Banin, Jude S Bimela, Michael Tuen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c4106728b04dd953defa6fd9a4f99db
https://doi.org/10.37247/pai.1.2020.4
https://doi.org/10.37247/pai.1.2020.4
Autor:
Ralf Duerr, Andrew N. Banin, I. O. Okonko, Jude S. Bimela, Dora Mbanya, Aubin Nanfack, Paul Zappile, Xiao-Hong Wang, Adriana Heguy, Jeanne Ngogang, Alireza Khodadadi-Jamayran, Marcel Tongo, Josephine Meli, Michael Tuen, Charles Fokunang, Miroslaw K. Gorny
Publikováno v:
Journal of the International AIDS Society
Introduction In Cameroon, a manifold diversity of HIV strains exists with CRF02_AG and unique recombinant forms (URFs) being the predominant strains. In recent years, a steady increase in URFs and clade F2 viruses has been monitored through partial g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4262b572657c9dde5af2cd5705bfd3
http://europepmc.org/articles/PMC6661401
http://europepmc.org/articles/PMC6661401
Autor:
Nathan D. Wolfe, Stuart C. Ray, Jude S. Bimela, Judith N. Torimiro, Eitel Mpoudi-Ngole, Desire Takou, Maurice Boda, Dale M. Netski, Oudou Njoya, Laure Tchapda, Donald S. Burke, Ubald Tamoufe, Wilfred Fon Mbacham, Henry Luma
Publikováno v:
British Microbiology Research Journal. 17:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65748b583c6265a67c923c1bddda8c47
https://doi.org/10.9734/bmrj/2016/28823
https://doi.org/10.9734/bmrj/2016/28823