Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Jude M. Przyborski"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
As part of their life-cycle, malaria parasites undergo rapid cell multiplication and division, with one parasite giving rise to over 20 new parasites within the course of 48 h. To support this, the parasite has an extremely high metabolic rate and le
Externí odkaz:
https://doaj.org/article/037fe3037bb84b988283d8fc2524e96f
Autor:
Maneesh K. Singh, Giulliana Tessarin-Almeida, Barbara K. M. Dias, Pedro Scarpellli Pereira, Fahyme Costa, Jude M. Przyborski, Celia R. S. Garcia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The host hormone melatonin is known to modulate the asexual cell-cycle of the human malaria parasite Plasmodium falciparum and the kinase PfPK7 is fundamental in the downstream signaling pathways. The nuclear protein PfMORC displays a histid
Externí odkaz:
https://doaj.org/article/56eac78196474ce4a12acb089a0710f1
Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence.
Autor:
Mathias Diehl, Lena Roling, Lukas Rohland, Sebastian Weber, Marek Cyrklaff, Cecilia P Sanchez, Carlo A Beretta, Caroline S Simon, Julien Guizetti, Julia Hahn, Norma Schulz, Matthias P Mayer, Jude M Przyborski
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009969 (2021)
The pathology associated with malaria infection is largely due to the ability of infected human RBCs to adhere to a number of receptors on endothelial cells within tissues and organs. This phenomenon is driven by the export of parasite-encoded protei
Externí odkaz:
https://doaj.org/article/ad3aa796df9c4134ab9f7afc1411acec
Autor:
Sandra Bennink, Andreas von Bohl, Che J Ngwa, Leonie Henschel, Andrea Kuehn, Nicole Pilch, Tim Weißbach, Alina N Rosinski, Matthias Scheuermayer, Urska Repnik, Jude M Przyborski, Allen M Minns, Lindsey M Orchard, Gareth Griffiths, Scott E Lindner, Manuel Llinás, Gabriele Pradel
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007249 (2018)
The complex life-cycle of the human malaria parasite Plasmodium falciparum requires a high degree of tight coordination allowing the parasite to adapt to changing environments. One of the major challenges for the parasite is the human-to-mosquito tra
Externí odkaz:
https://doaj.org/article/524c2973888440ce8e6bba3516359498
Autor:
Peter Herbener, Kurt Schönfeld, Martin König, Matthias Germer, Jude M Przyborski, Katrin Bernöster, Jörg Schüttrumpf
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195823 (2018)
An increasing number of monoclonal antibodies and derivatives such as antibody-drug conjugates (ADC) are of the IgG1 and IgG4 isotype with distinct structural and functional properties. In cases where antibody-mediated cytotoxicity is not desired, Ig
Externí odkaz:
https://doaj.org/article/5cd5401408894dbc9333986fdcb6d1d0
Autor:
Carine F. Djuika, Jaime Huerta-Cepas, Jude M. Przyborski, Sophia Deil, Cecilia P. Sanchez, Tobias Doerks, Peer Bork, Michael Lanzer, Marcel Deponte
Publikováno v:
Microbial Cell, Vol 2, Iss 1, Pp 5-13 (2015)
Horizontal gene transfer has emerged as a crucial driving force for the evolution of eukaryotes. This also includes Plasmodium falciparum and related economically and clinically relevant apicomplexan parasites, whose rather small genomes have been sh
Externí odkaz:
https://doaj.org/article/c9bdf538bcf34ecfb4178e6c6e0ae2df
Autor:
Sarah C Charnaud, Matthew W A Dixon, Catherine Q Nie, Lia Chappell, Paul R Sanders, Thomas Nebl, Eric Hanssen, Matthew Berriman, Jo-Anne Chan, Adam J Blanch, James G Beeson, Julian C Rayner, Jude M Przyborski, Leann Tilley, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181656 (2017)
Malaria is caused by five different Plasmodium spp. in humans each of which modifies the host erythrocyte to survive and replicate. The two main causes of malaria, P. falciparum and P. vivax, differ in their ability to cause severe disease, mainly du
Externí odkaz:
https://doaj.org/article/9c7a23a7856f435780cc653721a9fc78
Publikováno v:
Biomolecules, Vol 9, Iss 7, p 295 (2019)
The survival of the human malaria parasite Plasmodium falciparum under the physiologically distinct environments associated with their development in the cold-blooded invertebrate mosquito vectors and the warm-blooded vertebrate human host requires a
Externí odkaz:
https://doaj.org/article/e36830931bdf4f418ffbaf83451ec7fb
Autor:
Célia R.S. Garcia, Maneesh Kumar Singh, Fahyme Costa, Bárbara K M Dias, Giulliana Tessarin-Almeida, Jude M. Przyborski, Pedro Scarpellli Pereira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
The host hormone melatonin is known to modulate the asexual cell-cycle of the human malaria parasite Plasmodium falciparum and the kinase PfPK7 is fundamental in the downstream signaling pathways. The nuclear protein PfMORC displays a histidine kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650d496e15ea8dc00475ee58207d7e4d
https://doaj.org/article/56eac78196474ce4a12acb089a0710f1
https://doaj.org/article/56eac78196474ce4a12acb089a0710f1
Autor:
Apelele Ntlantsana, Heinrich C. Hoppe, Tarryn Swart, Farrah D. Khan, Jude M. Przyborski, Dustin Laming, Adrienne L. Edkins, Clinton G. L. Veale
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The regulation of human Arf1 GTPase activity by ArfGEFs that stimulate GDP/GTP exchange and ArfGAPs that mediate GTP hydrolysis has attracted attention for the discovery of Arf1 inhibitors as potential anti-cancer agents. The malaria parasite Plasmod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edfb458bddfc4a64becd402917e6212
http://link.springer.com/article/10.1038/s41598-020-61101-3
http://link.springer.com/article/10.1038/s41598-020-61101-3