Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Jude M Przyborski"'
Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence.
Autor:
Mathias Diehl, Lena Roling, Lukas Rohland, Sebastian Weber, Marek Cyrklaff, Cecilia P Sanchez, Carlo A Beretta, Caroline S Simon, Julien Guizetti, Julia Hahn, Norma Schulz, Matthias P Mayer, Jude M Przyborski
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009969 (2021)
The pathology associated with malaria infection is largely due to the ability of infected human RBCs to adhere to a number of receptors on endothelial cells within tissues and organs. This phenomenon is driven by the export of parasite-encoded protei
Externí odkaz:
https://doaj.org/article/ad3aa796df9c4134ab9f7afc1411acec
Autor:
Sandra Bennink, Andreas von Bohl, Che J Ngwa, Leonie Henschel, Andrea Kuehn, Nicole Pilch, Tim Weißbach, Alina N Rosinski, Matthias Scheuermayer, Urska Repnik, Jude M Przyborski, Allen M Minns, Lindsey M Orchard, Gareth Griffiths, Scott E Lindner, Manuel Llinás, Gabriele Pradel
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007249 (2018)
The complex life-cycle of the human malaria parasite Plasmodium falciparum requires a high degree of tight coordination allowing the parasite to adapt to changing environments. One of the major challenges for the parasite is the human-to-mosquito tra
Externí odkaz:
https://doaj.org/article/524c2973888440ce8e6bba3516359498
Autor:
Peter Herbener, Kurt Schönfeld, Martin König, Matthias Germer, Jude M Przyborski, Katrin Bernöster, Jörg Schüttrumpf
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195823 (2018)
An increasing number of monoclonal antibodies and derivatives such as antibody-drug conjugates (ADC) are of the IgG1 and IgG4 isotype with distinct structural and functional properties. In cases where antibody-mediated cytotoxicity is not desired, Ig
Externí odkaz:
https://doaj.org/article/5cd5401408894dbc9333986fdcb6d1d0
Autor:
Sarah C Charnaud, Matthew W A Dixon, Catherine Q Nie, Lia Chappell, Paul R Sanders, Thomas Nebl, Eric Hanssen, Matthew Berriman, Jo-Anne Chan, Adam J Blanch, James G Beeson, Julian C Rayner, Jude M Przyborski, Leann Tilley, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181656 (2017)
Malaria is caused by five different Plasmodium spp. in humans each of which modifies the host erythrocyte to survive and replicate. The two main causes of malaria, P. falciparum and P. vivax, differ in their ability to cause severe disease, mainly du
Externí odkaz:
https://doaj.org/article/9c7a23a7856f435780cc653721a9fc78
Publikováno v:
Frontiers in Molecular Biosciences, Vol 2 (2015)
The human malaria parasite, Plasmodium falciparum, encodes a minimal complement of six heat shock protein 70s (PfHSP70s), some of which are highly expressed and are thought to play an important role in the survival and pathology of the parasite. In a
Externí odkaz:
https://doaj.org/article/3ac2995928f041fc86c7c3348a819563
Autor:
Tawanda Zininga, Stanely Makumire, Grace Wairimu Gitau, James M Njunge, Ofentse Jacob Pooe, Hanna Klimek, Robina Scheurr, Hartmann Raifer, Earl Prinsloo, Jude M Przyborski, Heinrich Hoppe, Addmore Shonhai
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135326 (2015)
Heat shock proteins (Hsps) play an important role in the development and pathogenicity of malaria parasites. One of the most prominent functions of Hsps is to facilitate the folding of other proteins. Hsps are thought to play a crucial role when mala
Externí odkaz:
https://doaj.org/article/c372766316374282b3d63932538ba1a0
Autor:
Thuvaraka Thavayogarajah, Preetish Gangopadhyay, Stefan Rahlfs, Katja Becker, Klaus Lingelbach, Jude M Przyborski, Anthony A Holder
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125191 (2015)
Plasmodium falciparum invades human red blood cells, residing in a parasitophorous vacuole (PV), with a parasitophorous vacuole membrane (PVM) separating the PV from the host cell cytoplasm. Here we have investigated the role of N-myristoylation and
Externí odkaz:
https://doaj.org/article/e5742749bdb24b33a8e9c913b2b38709
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18396 (2011)
Upon invading the host erythrocyte, the human malaria parasite P. falciparum lives and replicates within a membrane bound compartment referred to as the parasitophorous vacuole. Recently, interest in this compartment and its protein content has grown
Externí odkaz:
https://doaj.org/article/b9d33d7636564e81a30eee6b5af5c8c6
Publikováno v:
PLoS Pathogens, Vol 6, Iss 12, p e1001242 (2010)
Malaria, caused by the apicomplexan parasite Plasmodium, still represents a major threat to human health and welfare and leads to about one million human deaths annually. Plasmodium is a rapidly multiplying unicellular organism undergoing a complex d
Externí odkaz:
https://doaj.org/article/66c556ad33584bada5a16b64eef34790
Publikováno v:
Frontiers in Molecular Biosciences. 9
As part of their life-cycle, malaria parasites undergo rapid cell multiplication and division, with one parasite giving rise to over 20 new parasites within the course of 48 h. To support this, the parasite has an extremely high metabolic rate and le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b074ee90f480264a83d119369d1c2b
https://doi.org/10.3389/fmolb.2022.968248
https://doi.org/10.3389/fmolb.2022.968248