Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jude Gibson"'
Autor:
Nicholas T. Ventham, Nicholas A. Kennedy, Rahul Kalla, Alex T. Adams, Alexandra Noble, Holly Ennis, Craig Mowat, Malcolm G. Dunlop, Jack Satsangi, Ian Arnott, Aiden Cahill, Malcolm Smith, Tariq Ahmad, Sreedhar Subramanian, Simon Travis, John Morris, John Hamlin, Anjan Dhar, Chuka Nwokolo, Cathryn Edwards, Tom Creed, Stuart Bloom, Mohamed Yousif, Linzi Thomas, Simon Campbell, Stephen J. Lewis, Shaji Sebastian, Sandip Sen, Simon Lal, Chris Hawkey, Charles Murray, Fraser Cummings, Jason Goh, James O. Lindsay, Naila Arebi, Lindsay Potts, Aileen J. McKinley, John M. Thomson, John A. Todd, Mhairi Collie, Ashley Mowat, Daniel R. Gaya, Jack Winter, Graham D. Naismith, Catriona Keerie, Steff Lewis, Robin J. Prescott, Gordan Lauc, Harry Campbell, Dermot P.B. McGovern, Vito Annese, Vlatka Zoldoš, Iain K. Permberton, Manfred Wuhrer, Daniel Kolarich, Daryl L. Fernandes, Evropi Theorodorou, Victoria Merrick Daniel I. Spencer, Richard A. Gardner, Ray Doran, Archana Shubhakar, Ray Boyapati, Igor Rudan, Paolo Lionetti, Irena Trbojević Akmačić, Jasminka Krištić, Frano Vuč ković, Jerko Štambuk, Mislav Novokmet, Maja Pučić-Baković, Olga Gornik, Angelo Andriulli, Laura Cantoro, Giancarlo Sturniolo, Gionata Fiorino, Natalia Manetti, Anna Latiano, Anna Kohn, Renata D’Inca`, Silvio Danese, Ian D. Arnott, Colin L. Noble, Charlie W. Lees, Alan G. Shand, Gwo-Tzer Ho, Lee Murphy, Jude Gibson, Louise Evenden, Nicola Wrobel, Tamara Gilchrist, Angie Fawkes, Guinevere S.M. Kammeijer, Florent Clerc, Noortje de Haan, Aleksandar Vojta, Ivana Samaržija, Dora Markulin, Marija Klasić, Paula Dobrinić, Yurii Aulchenko, Tim van den Heuve, Daisy Jonkers, Marieke Pierik
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 431-450 (2023)
Background & Aims: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA me
Externí odkaz:
https://doaj.org/article/f32b67ecfa854c6487a3c5196a5070e3
Autor:
Jude Gibson, Tom C Russ, Toni-Kim Clarke, David M Howard, Robert F Hillary, Kathryn L Evans, Rosie M Walker, Mairead L Bermingham, Stewart W Morris, Archie Campbell, Caroline Hayward, Alison D Murray, David J Porteous, Steve Horvath, Ake T Lu, Andrew M McIntosh, Heather C Whalley, Riccardo E Marioni
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008104 (2019)
'Epigenetic age acceleration' is a valuable biomarker of ageing, predictive of morbidity and mortality, but for which the underlying biological mechanisms are not well established. Two commonly used measures, derived from DNA methylation, are Horvath
Externí odkaz:
https://doaj.org/article/a3ae5f4eb91544119f3e3c5d7fd25cbe
Autor:
David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, andMe Research Team, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The UK Biobank provides data for three depression-related phenotypes. Here, Howard et al. perform a genome-association study for broad depression, probable major depressive disorder (MDD) and hospital record-coded MDD in up to 322,580 UK Biobank part
Externí odkaz:
https://doaj.org/article/adf50ca61d2649f090bd2c0b4964ced4
Autor:
Daniel L. McCartney, Anna J. Stevenson, Rosie M. Walker, Jude Gibson, Stewart W. Morris, Archie Campbell, Alison D. Murray, Heather C. Whalley, David J. Porteous, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Riccardo E. Marioni
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 429-437 (2018)
Abstract Introduction The “epigenetic clock” is a DNA methylation–based estimate of biological age and is correlated with chronological age—the greatest risk factor for Alzheimer's disease (AD). Genetic and environmental risk factors exist fo
Externí odkaz:
https://doaj.org/article/068ba3cfc2ac4574980de1c560669065
Autor:
David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
Externí odkaz:
https://doaj.org/article/3ddd7a0a0fc3478cb27009f5f226119d
Autor:
David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, andMe Research Team, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22411-w
Externí odkaz:
https://doaj.org/article/315e3d990f874295aff7507c04c20fa8
Autor:
Michael M Mendelson, Riccardo E Marioni, Roby Joehanes, Chunyu Liu, Åsa K Hedman, Stella Aslibekyan, Ellen W Demerath, Weihua Guan, Degui Zhi, Chen Yao, Tianxiao Huan, Christine Willinger, Brian Chen, Paul Courchesne, Michael Multhaup, Marguerite R Irvin, Ariella Cohain, Eric E Schadt, Megan L Grove, Jan Bressler, Kari North, Johan Sundström, Stefan Gustafsson, Sonia Shah, Allan F McRae, Sarah E Harris, Jude Gibson, Paul Redmond, Janie Corley, Lee Murphy, John M Starr, Erica Kleinbrink, Leonard Lipovich, Peter M Visscher, Naomi R Wray, Ronald M Krauss, Daniele Fallin, Andrew Feinberg, Devin M Absher, Myriam Fornage, James S Pankow, Lars Lind, Caroline Fox, Erik Ingelsson, Donna K Arnett, Eric Boerwinkle, Liming Liang, Daniel Levy, Ian J Deary
Publikováno v:
PLoS Medicine, Vol 14, Iss 1, p e1002215 (2017)
BackgroundThe link between DNA methylation, obesity, and adiposity-related diseases in the general population remains uncertain.Methods and findingsWe conducted an association study of body mass index (BMI) and differential methylation for over 400,0
Externí odkaz:
https://doaj.org/article/56619ceba5414f799e1f7b502d4b541e
Autor:
Andrew M McIntosh, Lynsey S Hall, Yanni Zeng, Mark J Adams, Jude Gibson, Eleanor Wigmore, Saskia P Hagenaars, Gail Davies, Ana Maria Fernandez-Pujals, Archie I Campbell, Toni-Kim Clarke, Caroline Hayward, Chris S Haley, David J Porteous, Ian J Deary, Daniel J Smith, Barbara I Nicholl, David A Hinds, Amy V Jones, Serena Scollen, Weihua Meng, Blair H Smith, Lynne J Hocking
Publikováno v:
PLoS Medicine, Vol 13, Iss 8, p e1002090 (2016)
BackgroundChronic pain is highly prevalent and a significant source of disability, yet its genetic and environmental risk factors are poorly understood. Its relationship with major depressive disorder (MDD) is of particular importance. We sought to t
Externí odkaz:
https://doaj.org/article/8f71b918dc974bb39e192772bb999d22
Autor:
Claire Schwab, Ruth E. Cranston, Sarra L. Ryan, Ellie Butler, Emily Winterman, Zoe Hawking, Matthew Bashton, Amir Enshaei, Lisa J. Russell, Zoya Kingsbury, John F. Peden, Emilio Barretta, James Murray, Jude Gibson, Andrew C. Hinchliffe, Robert Bain, Ajay Vora, David R. Bentley, Mark T. Ross, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Leukemia. 37:529-538
Incorporating genetics into risk-stratification for treatment of childhood B-progenitor acute lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about 30% B-ALL (B-other-ALL) without well-established chromosomal ch
Autor:
Amir Enshaei, Javier Martinez Martínez Elicegui, Esther Anguiano, Jude Gibson, Mirella Ampatzidou, Michael Doubek, Adele K. Fielding, Edoardo La Sala, Elizabeth Middleton, Anita W. Rijneveld, Amin T. Turki, Ajay Vora, Martin Zimmermann, Anthony V. Moorman
Publikováno v:
Blood. 140:6369-6370